[ sulge aken ]
Elulookirjeldus (CV) | ||
1. | Eesnimi | Meeme |
2. | Perekonnanimi | Utt |
3. | Töökoht | Tartu Ülikool |
4. | Ametikoht | vanemteadur |
5. | Sünniaeg | 08.05.1960 (päev.kuu.aasta) |
6. | Haridus | kõrgem, Tartu Riiklik Ülikool 1983 |
7. | Teenistuskäik | 1983-1984 insener, TA Füüsika Instituut 1984-1985 nooremteadur, Keemilise Kineetika ja Katalüüsi Laboratoorium, TRÜ 1986-1989 aspirant, Orgaanilise keemia kateeder, TRÜ 1989-1990 nooremteadur, Orgaanilise keemia kateeder, TRÜ 1990-1992 teadur, Analüütilise Biokeemia Laboratoorium, TÜ 1992-1993 juhataja kt, Analüütilise Biokeemia Laboratoorium, TÜ 1994-1996 tegevdirektor, AS Bional 1997-1999 külalisteadur, Lundi Ülikool 1999-2002 doktorant, Lundi Ülikool 2002-2005 teadur, ÜMPI, TÜ 2005- vanemteadur, ÜMPI,TÜ |
8. | Teaduskraad | PhD |
9. | Teaduskraadi välja andnud asutus, aasta |
Lundi Ülikool, 2002 |
10. | Tunnustused | |
11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
|
12. | Juhendamisel kaitstud väitekirjad |
|
13. | Teadustöö põhisuunad | 1. Immunogeensete valkude identifitseerimine proteoomika meetodite abil (2-DE, MALDI-TOF MS, bioinformaatika). 2. Antimikroobse toimega peptiidide uurimine. 3. Valkude interaktsioonid glükoosaminoglükaanidega |
14. | Jooksvad grandid | ETF 5525 |
15. | Teaduspublikatsioonid |
K.E.Kisand, M.Utt, K.V.Kisand, T.Prükk, R.Uibo. Serological description of Estonian patients with Lyme disease, a comparison with control sera from endemic and non-endemic areas. Int J Med Microbiol. 2004 Suppl 37, 174-178 Oona M, Utt M, Nilsson I, Uibo O, Vorobjova T, Maaroos HI. Helicobacter pylori infection in children in Estonia: the decreasing seroprevalence during a 11-year period. Helicobacter, 2004, 9 (3), 233-241 I. Kornilovska, I. Nilsson, M.Utt, Å. Ljungh, T. Wadström. Immunogenic proteins of Helicobacter pullorum, Helicobacter bilis and Helicobacter hepaticus identified by two-dimensional gel-electrophoresis and immunoblotting. Proteomics, 2002, 2 (6), 775-783 Immunogenic cell surface proteins of Helicobacter pylori PCT WO 02/077022 A1 (3.10.2002) Ljungh Asa, Nilsson Ingrid, Utt Meeme, Wadström Torkel I. Nilsson and M. Utt. 2002. Separation and surveys of proteins of Helicobacter pylori. J.Chromatography B, 771, 251–260 M. Utt, I. Nilsson, Å. Ljungh and T. Wadström Identification of novel immunogenic proteins of Helicobacter pylori by proteome technology. J.Immunol. Methods, 2002, 259(1-2), 1-10 Fallgren C., Utt M., Ljungh Å. Isolation and characterisation of a 17-kDa staphylococcal heparin-binding protein with broad specificity. J Medical Microbiology. 2001, 50(6), 547-558 Immunogenic cell surface proteins of Helicobacter pylori (April 2001) Immunogenic proteins of Helicobacter pullorum, Helicobacter bilis and Helicobacter hepaticus (June 2001) Meeme Utt, Bengt Danielsson and Torkel Wadström: H. pylori vacuolating cytotoxin binding to a putative cell surface receptor, heparan sulphate, studied by surface plasmon resonance. FEMS Immunology Med.Microbiol. 2001, 30, 109-113 Tamara Vorobjova, Olga Ananieva, Heidi-Ingrid Maaroos, Pentti Sipponen, Kaljo Villako, Meeme Utt, Ingrid Nilsson, Torkel Wadström and Raivo Uibo. Seropositivity to Helicobacter pylori heat shock protein 60 is strongly associated with intensity of chronic inflammation, particularly in antrum mucosa: an extension of an 18-year follow-up study of chronic gastritis in Saaremaa, Estonia FEMS Immunology Med.Microbiol.2001, 30, 143-149 Ingrid Nilsson, Meeme Utt, Hans-Olof Nilsson and Torkel Wadström: Two-dimentional electrophoretic and immunoblot analysis of cell surface proteins from spiral and coccoid forms of Helicobacter pylori type strain 17874. Electophoresis, 2000, 21(13), 2670-2677 Chmiela M, Paziak-Domanska B, Hirmo S, Rudnicka W, Utt M, Wadström T. 1998. Helicobacter pylori - interactions with phagocytes. In: Helicobacter pylori. Basic mechanisms to clinical cure 1999 (Hunt RH, Tytgat GNJ, Eds), pp. 90- 100. Kluwer Academic Publishers, Dordrecht, Boston, London. Fallgren C., Utt M., Petersson AC., Ljungh A., Wadstrom T.: In vitro anti-staphylococcal activity of heparinized biomaterials bonded with combinations of rifampicin. Zentralbl Bakteriol 1998, 287(1-2), 19-31 Hirmo S, Utt M, Wadström T. 1998. Sialylglycoconjugate- and proteoglycan-binding microbial lectins. In: Lectins: Biology, Biochemistry, Clinical Biochemistry (van Driessche E, Beekmans S, Bfg-Hansen TC, Eds.) Vol. 12, Textop, Hellerup, Denmark. Hirmo S, Shumakov Y, Utt M, Wadström T. 1997. Genetic heterogeneity ofHelicobacter pylori and strain typing. In: Pathogenesis and Host Response in Helicobacter pylori Infections (Moran AP, O´Morain CA, Eds.), pp. 199-205, Normed Verlag, Bad Hamburg-Englewood, N.J. M. Utt and T. Wadström: Identification of heparan sulphate binding surface proteins of Helicobacter pylori: inhibition of heparan sulphate binding with sulphated carbohydrates polymers. J.Med. Microbiol. 1997, 46, 541-546 Siiri Hirmo, Meeme Utt and Torkel Wadström. Sialylglycoconjugate- and proteoglycan-binding microbial lectins http://plab.ku.dk/tcbh/Lectins12/Hirmo/paper.htm The Electronic Lectin Journal: Lectins, Biology, Biochemistry, ClinicalBiochemistry , Volume 12 , Accepted 18 december 1997, Editors Edilbert van Driessche, Sonia Beeckmans, Thorkild C. Bøg-Hansen Torkel Wadström, Siiri Hirmo, Hajdi Novak, Antonio Guzman, Martina Ringer-Pantzer, Meeme Utt, Pär Aleljung: Sulfatides inhibit binding of Helicobacter pylori to the gastric cancer Kato III cell line. Current Microbiology: 1997, 34, 267-272 Siiri Hirmo, Meeme Utt, Martina Ringer and Torkel Wadström: Inhibition of heparan sulphate and other glycosaminoglycans to Helicobacter pylori by various polysulphated carbohydrates. FEMS Immunology and Medical Microbiology: 1995, 10, 301-306 T. Wadström, F.Ascencio, Å.Ljungh, J.Lelwala-Guruge, M.Ringer, M.Utt, K.Valkonen Helicobacter pylori adhesins. European Journal of Gastroenterology and Hepatology: 1993, 5 (suppl 2) S 12-15, |
viimati muudetud: 12.10.2005
Curriculum Vitae (CV) | ||
1. | First Name | Meeme |
2. | Surname | Utt |
3. | Institution | University of Tartu |
4. | Position | senior research fellow |
5. | Date of birth | 08.05.1960 (day.month.year) |
6. | Education | higher, Tartu State University 1983 |
7. | Research and professional experience |
1983-1984 Engineer at Institute of Physics 1984-1985 Junior researcher at Tartu State University, Laboratory of Chemical Kinetics and Catalysis 1989-1990 Junior researcher at Department of Organic Chemistry 1990-1992 Research associate Laboratory of Analytical Biochemistry 1992 -1993 Head of Laboratory of Analytical Biochemistry, University of Tartu 1994 Researcher at Institute of Organic Chemistry 1994-1996 Managing Director at Bional Ltd 1997-1999 Visiting researcher at Lund, University, Sweden 1999-2002 PhD student, Lund University 2002-2005 researcher, University of Tartu 2005- senior reseacher, University of Tartu |
8. | Academic degree | PhD |
9. | Dates and sites of earning the degrees |
University of Lund, 2002 |
10. | Honours/awards | |
11. | Research-administrative experience |
|
12. | Supervised dissertations | |
13. | Current research program | 1. Identification of immunogenic proteins using methods of proteomics (2-DE, MALDI-TOF MS, bioinformatics) 2. Antimicrobial peptides 3. Protein interactions with glycosaminoglycans |
14. | Current grant funding | EstSF 5525 |
15. | List of most important publications |
K.E.Kisand, M.Utt, K.V.Kisand, T.Prükk, R.Uibo. Serological description of Estonian patients with Lyme disease, a comparison with control sera from endemic and non-endemic areas. Int J Med Microbiol. 2004 Suppl 37, 174-178 Oona M, Utt M, Nilsson I, Uibo O, Vorobjova T, Maaroos HI. Helicobacter pylori infection in children in Estonia: the decreasing seroprevalence during a 11-year period. Helicobacter, 2004, 9 (3), 233-241 I. Kornilovska, I. Nilsson, M.Utt, Å. Ljungh, T. Wadström. Immunogenic proteins of Helicobacter pullorum, Helicobacter bilis and Helicobacter hepaticus identified by two-dimensional gel-electrophoresis and immunoblotting. Proteomics, 2002, 2 (6), 775-783 Immunogenic cell surface proteins of Helicobacter pylori PCT WO 02/077022 A1 (3.10.2002) Ljungh Asa, Nilsson Ingrid, Utt Meeme, Wadström Torkel I. Nilsson and M. Utt. 2002. Separation and surveys of proteins of Helicobacter pylori. J.Chromatography B, 771, 251–260 M. Utt, I. Nilsson, Å. Ljungh and T. Wadström Identification of novel immunogenic proteins of Helicobacter pylori by proteome technology. J.Immunol. Methods, 2002, 259(1-2), 1-10 Fallgren C., Utt M., Ljungh Å. Isolation and characterisation of a 17-kDa staphylococcal heparin-binding protein with broad specificity. J Medical Microbiology. 2001, 50(6), 547-558 Immunogenic cell surface proteins of Helicobacter pylori (April 2001) Immunogenic proteins of Helicobacter pullorum, Helicobacter bilis and Helicobacter hepaticus (June 2001) Meeme Utt, Bengt Danielsson and Torkel Wadström: H. pylori vacuolating cytotoxin binding to a putative cell surface receptor, heparan sulphate, studied by surface plasmon resonance. FEMS Immunology Med.Microbiol. 2001, 30, 109-113 Tamara Vorobjova, Olga Ananieva, Heidi-Ingrid Maaroos, Pentti Sipponen, Kaljo Villako, Meeme Utt, Ingrid Nilsson, Torkel Wadström and Raivo Uibo. Seropositivity to Helicobacter pylori heat shock protein 60 is strongly associated with intensity of chronic inflammation, particularly in antrum mucosa: an extension of an 18-year follow-up study of chronic gastritis in Saaremaa, Estonia FEMS Immunology Med.Microbiol.2001, 30, 143-149 Ingrid Nilsson, Meeme Utt, Hans-Olof Nilsson and Torkel Wadström: Two-dimentional electrophoretic and immunoblot analysis of cell surface proteins from spiral and coccoid forms of Helicobacter pylori type strain 17874. Electophoresis, 2000, 21(13), 2670-2677 Chmiela M, Paziak-Domanska B, Hirmo S, Rudnicka W, Utt M, Wadström T. 1998. Helicobacter pylori - interactions with phagocytes. In: Helicobacter pylori. Basic mechanisms to clinical cure 1999 (Hunt RH, Tytgat GNJ, Eds), pp. 90- 100. Kluwer Academic Publishers, Dordrecht, Boston, London. Fallgren C., Utt M., Petersson AC., Ljungh A., Wadstrom T.: In vitro anti-staphylococcal activity of heparinized biomaterials bonded with combinations of rifampicin. Zentralbl Bakteriol 1998, 287(1-2), 19-31 Hirmo S, Utt M, Wadström T. 1998. Sialylglycoconjugate- and proteoglycan-binding microbial lectins. In: Lectins: Biology, Biochemistry, Clinical Biochemistry (van Driessche E, Beekmans S, Bfg-Hansen TC, Eds.) Vol. 12, Textop, Hellerup, Denmark. Hirmo S, Shumakov Y, Utt M, Wadström T. 1997. Genetic heterogeneity ofHelicobacter pylori and strain typing. In: Pathogenesis and Host Response in Helicobacter pylori Infections (Moran AP, O´Morain CA, Eds.), pp. 199-205, Normed Verlag, Bad Hamburg-Englewood, N.J. M. Utt and T. Wadström: Identification of heparan sulphate binding surface proteins of Helicobacter pylori: inhibition of heparan sulphate binding with sulphated carbohydrates polymers. J.Med. Microbiol. 1997, 46, 541-546 Siiri Hirmo, Meeme Utt and Torkel Wadström. Sialylglycoconjugate- and proteoglycan-binding microbial lectins http://plab.ku.dk/tcbh/Lectins12/Hirmo/paper.htm The Electronic Lectin Journal: Lectins, Biology, Biochemistry, ClinicalBiochemistry , Volume 12 , Accepted 18 december 1997, Editors Edilbert van Driessche, Sonia Beeckmans, Thorkild C. Bøg-Hansen Torkel Wadström, Siiri Hirmo, Hajdi Novak, Antonio Guzman, Martina Ringer-Pantzer, Meeme Utt, Pär Aleljung: Sulfatides inhibit binding of Helicobacter pylori to the gastric cancer Kato III cell line. Current Microbiology: 1997, 34, 267-272 Siiri Hirmo, Meeme Utt, Martina Ringer and Torkel Wadström: Inhibition of heparan sulphate and other glycosaminoglycans to Helicobacter pylori by various polysulphated carbohydrates. FEMS Immunology and Medical Microbiology: 1995, 10, 301-306 T. Wadström, F.Ascencio, Å.Ljungh, J.Lelwala-Guruge, M.Ringer, M.Utt, K.Valkonen Helicobacter pylori adhesins. European Journal of Gastroenterology and Hepatology: 1993, 5 (suppl 2) S 12-15, |
last updated: 12.10.2005
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