[ sulge aken ]
| Elulookirjeldus (CV) | ||
| 1. | Eesnimi | Margus |
| 2. | Perekonnanimi | Lopp |
| 3. | Töökoht | Tallinna Tehnikaülikool |
| 4. | Ametikoht | professor |
| 5. | Sünniaeg | 11.09.1949 (päev.kuu.aasta) |
| 6. | Haridus | TRÜ Füüsika-keemiateaduskond, 1968-1973; TA Keemia Instituudi aspirantuur 1977-1981,keemiateaduste kandidaat TA Keemia Instituut 1981; Budapesti Keemiainstituut 1977- 3 kuud külalisteadur; 1981-3 kuud külalisteadur; East Anglia Ülikool 1989-1990-3kuud külalisteadur |
| 7. | Teenistuskäik | Keemia Instituut, vaneminsener 1973-1976; nooremteadur 1976-1981; vanemteadur 1981-1986; juhtiv teadur 1986-1991; TTÜ orgaanilise keemia professor, orgaanilise keemia õppetooli juhataja 1997-; Helsinki Ülikooli dotsent 1993-. |
| 8. | Teaduskraad | keemiateaduste kandidaat |
| 9. | Teaduskraadi välja andnud asutus, aasta |
TA Keemia Instituut 1981 |
| 10. | Tunnustused | ENSV Riiklik teaduspreemia 1987; NSVL RMSN hõbemedal 1986, Eesti Vabariigi teaduspreemia 2004 |
| 11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
1981-1991-Keemia Instituudi prostanoidide sektori sünteesigrupi juht; 1992-2002-orgaanilise sünteesi osakonna juhataja; 1997-2004 TTÜ alus-ja rakenduskeemia instituudi(alates 2002 keemiainstituut) direktor; alates 2004 TTÜ Matemaatika -Loodusteaduskonna dekaan, TTÜ nõukogu liige; 1997-2004 Eesti Keemia Seltsi viitsepresident, alates 2004 Eesti Keemia Seltsi president |
| 12. | Juhendamisel kaitstud väitekirjad |
Riina Aav, PhD, 2005, juh. Margus Lopp, Tõnis Kanger. Synthesis of 9,11-Secosterols Intermediates. TTÜ Imre Vallikivi, DSc, 2004, juh. Margus Lopp, Omar Parve. Lipase-catalysed Reactions of Prostaglandins. TTÜ Monika Übner, PhD, 2004, juh. Margus Lopp. Interactions of Humic Substances with Metal Cations. TTÜ Allan Niidu, MSc, 2003, juh. Margus Lopp. Karbatsüklid kui võimalikud nukeosiidide analoogide prekursorid Caracyclic compounds as precursors for nucloside analogues. TTÜ. TTÜ Kadri Kriis, PhD, 2003, juh. Margus Lopp, Tõnis Kanger. Asymmetric synthesis of C2-symmetric bimorpholines and their application as chiral ligands in the transfer hydrogenation of aromatic ketones. TTÜ Jaak Suurpere, MSc, 2002, juh. Margus Lopp. Asendatud 1,2-etüleendiamiinide fragmentatsioon. TTÜ Janek Peterson, PhD, 2002, juh. Margus Lopp. Synthesis, Structural Characterization and Modification of PAMAM Dendrimers. TTÜ Anne Paju, PhD, 2001, juh. Margus Lopp. Asymmetric oxidation of prochiral and racemic ketones by using Sharpless catalyst. TTÜ Kadri Kriis, MSc, 1999, juh. Margus Lopp, Tõnis Kanger. Tsüklobutanoonide asümmeetriline oksüdeerimine modifitseeritud Sharplessi reagendiga. TTÜ Anne Paju, MSc, 1992, juh. Margus Lopp. Prostaglandiinide E ja F analoogide süntees kupraatmeetodil. TÜ Omar Parve, cand, 1990, juh. Margus Lopp. Prostaglandiin I2 karbotsükliliste analoogide süntees. TA Keemia Instituut Tõnis Kanger, cand, 1990, juh. Margus Lopp, Ülo Lille. Bitsüklilised oksiraanid ja liitium/BF3 reagent prostaglandiinide enantiomeersete vaheühendite sünteesil. Ta Keemia Instituut Madis Lõhmus, cand, 1989, juh. Margus Lopp, Ülo Lille. Prostaglandiinide, nende analoogide ja vaheühendite isomeerse koostise uurimine ning nende lahutusmeetodite väljatöötamine vedelikkromatograafilisel meetodil. TA Keemia Instituut |
| 13. | Teadustöö põhisuunad | Stereokeemia, asümeetriline keemiline süntees, bioakstiivsete ja looduslike ühendite süntees, asümmeetriline katalüüs, kiraalsete ühendite analüüs |
| 14. | Jooksvad grandid | Karbonüülühendite asümmeetrilised muundumised ETF5628, 2004-2006; 0351761s01 „Uued selektiivsed asümmeetrilise sünteesi meetodid ja nende kasutamine bioaktiivsete ühendite saamiseks” 2001-2005 EV Haridusministeerium |
| 15. | Teaduspublikatsioonid |
Juhan Subbi, Reet Aguraiuja, Risto Tanner, Veiko Allikmaa and Margus Lopp. Fragmentation of poly(amidoamine) dendrimers in matrix-assisted laser desorption. European Polymer Journal, 41, Pages 2552-2558. Margus Lopp, Anne Paju, Tõnis Pehk, Margus Eek, Tõnis Kanger. Meetod (-)-R-homosidrunhappe ja (+)-S-homosidrunhappe laktoonide saamiseks. Patenditaotlus. EE 200400009 A, 15.08.2005. R.Aav, T.Kanger, T.Pehk, M.Lopp. Unexpected Reactivity of Ethyl 2-(Diethylphosphono)Propionate Towards 2,2-disubstituted -1,3-cyclopentanediones. Phosphorus, Sulfur, and Silicon. 2005,180,1739-1749. Tõnis Kanger, Kristi Raudla, Riina Aav, Aleksander-Mati Müürisepp, Tõnis Pehk, Margus Lopp. Synthesis of Bis-nor Wieland-Mieschner ketone. Synthesis. 2005, in press Anne Paju, Tõnis Kanger, Tõnis Pehk, Margus Eek and Margus Lopp. A short enantioselective synthesis of homocitric acid g-lactone and 4-hydroxy-homocitric acid g-lactones. Tetrahedron, Volume 60, 2004, 9081-9084 Kadri Kriis, Tõnis Kanger, Margus Lopp. Asymmetric transfer hydrogenation of aromatic ketones by Rh(I)/bimorpholine complexes. Tetrahedron: Asymmetry, 2004, 2687-2691. Monika Übner, Mihkel Kaljurand, Margus Lopp. Interactions of Pb2+ with fulvic acid by electriphoretically mediated on-capillary microanalysis J. Chromatography A. 2004, 253-256. Monika Übner, Viia Lepane, Margus Lopp, Mihkel Kaljurand. Electriphoretic aggregation of humic acid. J. Chromatography A. 2004, 253-258. 9. J. Peterson, V. Allikmaa, J. Subbi, T. Pehk, M. Lopp. Structural deviations in poly(amidoamine) dendrimers: a MALDI-TOF MS analysis. European Polymer Journal. 2003, 33-42 Anne Paju, Tõnis Kanger, Olivia Niitsoo, Tõnis Pehk, Aleksander-Mati Müürisepp, Margus Lopp. Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part 3. Oxidative Ring Clevage of 3-Alkyl-1,2-cyclopentanediones: synthesis of -hydroxy --lactone acids and spirodilactones. Tetrahedron: Asymmetry, 2003, 1565-1573. Anne Paju, Tõnis Kanger, Tõnis Pehk, Rasmus Lindmaa, Aleksander-Mati Müürisepp, Margus Lopp. Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part 2. Oxidative Ring Clevage of 3-Alkyl-1,2-cyclopentanediones: synthesis of 2-alkyl--lactone acids. Tetrahedron: Asymmetry, 2003, 1565-1573 Kadri Kriis, Tõnis Kanger, Aleksander-Mati Müürisepp, Margus Lopp. C-2-symmetric bimorpholines as chiral ligands in the asymmetric hydrogenation of ketones. Tetrahedron: Asymmetry, 2003, 2271-2275 Tõnis Kanger, Kerti Ausmees, Aleksander-Mati Müürisepp, Tõnis Pehk, Margus Lopp. A comparative Study of the Syntheis of C-2-symmetric Chiral 2,2’biaziridinyls. Synlett, 2003, 1055-1058. 10. Anne Paju, Tõnis Kanger, Tõnis Pehk, Margus Lopp. Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part I. 3-Hydroxylation of 3-Alkyl-1,2-cyclopentanediones. Tetrahedron: Asymmetry, 2002, 2439-2448 6. Tõnis Kanger, Kadri Kriis, Tõnis Pehk, Aleksander-Mati Müürisepp, Margus Lopp. Asymmetric synthesis of novel C2-symmetric bimorpholines. Tetrahedron: Asymmetry, 2002, 13, 857-865 A. Ebber, M.Vaher, J.Peterson, M.Lopp. Application of capillary zone electrophoresis to the separation and characterization of poly(amidoamine) dendrimers with an ethylenediamine core. J. Chromatography A. 2002, 351-358 Anne Paju, Tõnis Kanger, Tõnis Pehk and Margus Lopp. Direct asymmetric -hydroxylation of 2-hydroxymethyl ketones, Tetrahedron, Volume 58, 2002, 7321-7326 Anne Paju, Tõnis Kanger, Tõnis Pehk and Margus Lopp. Asymmetric oxidation of 1,2-cyclopentanediones. Tetrahedron Letters. 2000, 6883-6887. Riina Aav, Tõnis Kanger, Tõnis Pehk, Margus Lopp. Syntheis of AB-Ring of 9,11-secosterols. SYNLETT, 2000, 4, 529-531. Tõnis Kanger, Piret Niidas, Aleksander-Mati Müürisepp, Tõnis Pehk, Margus Lopp. Synthesis of chiral epoxyalkynes. Tetrahedron: Asymmetry. 1998, 2499-2508. M.Lopp, A.Paju, T. Kanger, T.Pehk. Aasymmetric Baeyer-Villiger oxidation of cyclobutanones. Tetrahedron. Lett., 1996, 37, 7583-7586. T.Pehk, E.Lippmaa, M.Lopp, A.Paju, B.C.Borer, R.J.K.Taylor. Determination of the absolute configuration of chiral secondary alcohols; new advances using 13C and 2D-NMR spectroscopy. Tetrahedron: Asymmetry. 1993, 4, 1527-1532. |
viimati muudetud: 15.10.2005
| Curriculum Vitae (CV) | ||
| 1. | First Name | Margus |
| 2. | Surname | Lopp |
| 3. | Institution | Tallinn University of Technology |
| 4. | Position | professor |
| 5. | Date of birth | 11.09.1949 (day.month.year) |
| 6. | Education | Tartu Universitry, Faculty of Physics and Chemistry,1968-1973; post graduate studies Institute of Chemistry, Estonian Academy of Sciences, 1977-1981; Budapest Central Institute for Chemistry 1977 3 months; 1981 3 months, University of East Anglia 1989-1990- 3 months |
| 7. | Research and professional experience |
Ssenior engineer of the Institute of Chemistry 1973-1976; junior researcher 1976-1981; senior researcher, 1981-1986; director researcher 1986-1991; Professor of Organic Chemistry at Tallinn University of Technology, Head of the Chair of Organic Chemsitry 1997-, Docent of the University of Helsinki 1993-. |
| 8. | Academic degree | Ph.D |
| 9. | Dates and sites of earning the degrees |
Institute of Chemistry, Estonian Academy of Sciences |
| 10. | Honours/awards | State Science Award of Estonia 1987; Siver Medal from the Moscow All-Union Exibition of Achievements 1986, State Science Award of Estonian Republic 2004. |
| 11. | Research-administrative experience |
1981-1991 head of the group of the chemical synthesis of prostaglandins; Head of the Department of Organic Synthesis 1992-2002; 1997-2004 Director of the Department of Chemistry of Tallinn University of Technology, 2004- Dean of the Faculty of Science, member of the University Councel, 1997-2004 Vice president of the Estonian Chemical Society, 2004-president of the Estonian Chemical Society |
| 12. | Supervised dissertations |
Riina Aav, PhD, 2005, superv. Margus Lopp, Tõnis Kanger. Synthesis of 9,11-Secosterols Intermediates. TTÜ Imre Vallikivi, DSc, 2004, superv. Margus Lopp, Omar Parve. Lipase-catalysed Reactions of Prostaglandins. TTÜ Monika Übner, PhD, 2004, superv. Margus Lopp. Interactions of Humic Substances with Metal Cations. TTÜ Allan Niidu, MSc, 2003, superv. Margus Lopp. Karbatsüklid kui võimalikud nukeosiidide analoogide prekursorid Caracyclic compounds as precursors for nucloside analogues. TTÜ. TTÜ Kadri Kriis, PhD, 2003, superv. Margus Lopp, Tõnis Kanger. Asymmetric synthesis of C2-symmetric bimorpholines and their application as chiral ligands in the transfer hydrogenation of aromatic ketones. TTÜ Jaak Suurpere, MSc, 2002, superv. Margus Lopp. Asendatud 1,2-etüleendiamiinide fragmentatsioon. TTÜ Janek Peterson, PhD, 2002, superv. Margus Lopp. Synthesis, Structural Characterization and Modification of PAMAM Dendrimers. TTÜ Anne Paju, PhD, 2001, superv. Margus Lopp. Asymmetric oxidation of prochiral and racemic ketones by using Sharpless catalyst. TTÜ Kadri Kriis, MSc, 1999, superv. Margus Lopp, Tõnis Kanger. Tsüklobutanoonide asümmeetriline oksüdeerimine modifitseeritud Sharplessi reagendiga. TTÜ Anne Paju, MSc, 1992, superv. Margus Lopp. Prostaglandiinide E ja F analoogide süntees kupraatmeetodil. TÜ Omar Parve, cand, 1990, superv. Margus Lopp. Prostaglandiin I2 karbotsükliliste analoogide süntees. TA Keemia Instituut Tõnis Kanger, cand, 1990, superv. Margus Lopp, Ülo Lille. Bitsüklilised oksiraanid ja liitium/BF3 reagent prostaglandiinide enantiomeersete vaheühendite sünteesil. Ta Keemia Instituut Madis Lõhmus, cand, 1989, superv. Margus Lopp, Ülo Lille. Prostaglandiinide, nende analoogide ja vaheühendite isomeerse koostise uurimine ning nende lahutusmeetodite väljatöötamine vedelikkromatograafilisel meetodil. TA Keemia Instituut |
| 13. | Current research program | Stereochemistry, asymmetric organic synthesis, synthesis of bioactive and natural products, asymmetric catalysis, analysis of chiral compounds |
| 14. | Current grant funding | Asymmetric transformation of carbonyl compounds Estonian Science Foundation ETF 5628, 2004-2006. New selective methods of asymmetric synthesis and their applications to the synthesis of bioactive compounds. Ministry of Education, 00351761s01, 2001-2005. |
| 15. | List of most important publications |
Juhan Subbi, Reet Aguraiuja, Risto Tanner, Veiko Allikmaa and Margus Lopp. Fragmentation of poly(amidoamine) dendrimers in matrix-assisted laser desorption. European Polymer Journal, 41, Pages 2552-2558. Margus Lopp, Anne Paju, Tõnis Pehk, Margus Eek, Tõnis Kanger. Meetod (-)-R-homosidrunhappe ja (+)-S-homosidrunhappe laktoonide saamiseks. Patenditaotlus. EE 200400009 A, 15.08.2005. R.Aav, T.Kanger, T.Pehk, M.Lopp. Unexpected Reactivity of Ethyl 2-(Diethylphosphono)Propionate Towards 2,2-disubstituted -1,3-cyclopentanediones. Phosphorus, Sulfur, and Silicon. 2005,180,1739-1749. Tõnis Kanger, Kristi Raudla, Riina Aav, Aleksander-Mati Müürisepp, Tõnis Pehk, Margus Lopp. Synthesis of Bis-nor Wieland-Mieschner ketone. Synthesis. 2005, in press Anne Paju, Tõnis Kanger, Tõnis Pehk, Margus Eek and Margus Lopp. A short enantioselective synthesis of homocitric acid g-lactone and 4-hydroxy-homocitric acid g-lactones. Tetrahedron, Volume 60, 2004, 9081-9084 Kadri Kriis, Tõnis Kanger, Margus Lopp. Asymmetric transfer hydrogenation of aromatic ketones by Rh(I)/bimorpholine complexes. Tetrahedron: Asymmetry, 2004, 2687-2691. Monika Übner, Mihkel Kaljurand, Margus Lopp. Interactions of Pb2+ with fulvic acid by electriphoretically mediated on-capillary microanalysis J. Chromatography A. 2004, 253-256. Monika Übner, Viia Lepane, Margus Lopp, Mihkel Kaljurand. Electriphoretic aggregation of humic acid. J. Chromatography A. 2004, 253-258. 9. J. Peterson, V. Allikmaa, J. Subbi, T. Pehk, M. Lopp. Structural deviations in poly(amidoamine) dendrimers: a MALDI-TOF MS analysis. European Polymer Journal. 2003, 33-42 Anne Paju, Tõnis Kanger, Olivia Niitsoo, Tõnis Pehk, Aleksander-Mati Müürisepp, Margus Lopp. Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part 3. Oxidative Ring Clevage of 3-Alkyl-1,2-cyclopentanediones: synthesis of -hydroxy --lactone acids and spirodilactones. Tetrahedron: Asymmetry, 2003, 1565-1573. Anne Paju, Tõnis Kanger, Tõnis Pehk, Rasmus Lindmaa, Aleksander-Mati Müürisepp, Margus Lopp. Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part 2. Oxidative Ring Clevage of 3-Alkyl-1,2-cyclopentanediones: synthesis of 2-alkyl--lactone acids. Tetrahedron: Asymmetry, 2003, 1565-1573 Kadri Kriis, Tõnis Kanger, Aleksander-Mati Müürisepp, Margus Lopp. C-2-symmetric bimorpholines as chiral ligands in the asymmetric hydrogenation of ketones. Tetrahedron: Asymmetry, 2003, 2271-2275 Tõnis Kanger, Kerti Ausmees, Aleksander-Mati Müürisepp, Tõnis Pehk, Margus Lopp. A comparative Study of the Syntheis of C-2-symmetric Chiral 2,2’biaziridinyls. Synlett, 2003, 1055-1058. 10. Anne Paju, Tõnis Kanger, Tõnis Pehk, Margus Lopp. Asymmetric Oxidation of 3-Alkyl-1,2-cyclopentanediones. Part I. 3-Hydroxylation of 3-Alkyl-1,2-cyclopentanediones. Tetrahedron: Asymmetry, 2002, 2439-2448 6. Tõnis Kanger, Kadri Kriis, Tõnis Pehk, Aleksander-Mati Müürisepp, Margus Lopp. Asymmetric synthesis of novel C2-symmetric bimorpholines. Tetrahedron: Asymmetry, 2002, 13, 857-865 A. Ebber, M.Vaher, J.Peterson, M.Lopp. Application of capillary zone electrophoresis to the separation and characterization of poly(amidoamine) dendrimers with an ethylenediamine core. J. Chromatography A. 2002, 351-358 Anne Paju, Tõnis Kanger, Tõnis Pehk and Margus Lopp. Direct asymmetric -hydroxylation of 2-hydroxymethyl ketones, Tetrahedron, Volume 58, 2002, 7321-7326 Anne Paju, Tõnis Kanger, Tõnis Pehk and Margus Lopp. Asymmetric oxidation of 1,2-cyclopentanediones. Tetrahedron Letters. 2000, 6883-6887. Riina Aav, Tõnis Kanger, Tõnis Pehk, Margus Lopp. Syntheis of AB-Ring of 9,11-secosterols. SYNLETT, 2000, 4, 529-531. Tõnis Kanger, Piret Niidas, Aleksander-Mati Müürisepp, Tõnis Pehk, Margus Lopp. Synthesis of chiral epoxyalkynes. Tetrahedron: Asymmetry. 1998, 2499-2508. M.Lopp, A.Paju, T. Kanger, T.Pehk. Aasymmetric Baeyer-Villiger oxidation of cyclobutanones. Tetrahedron. Lett., 1996, 37, 7583-7586. T.Pehk, E.Lippmaa, M.Lopp, A.Paju, B.C.Borer, R.J.K.Taylor. Determination of the absolute configuration of chiral secondary alcohols; new advances using 13C and 2D-NMR spectroscopy. Tetrahedron: Asymmetry. 1993, 4, 1527-1532. |
last updated: 15.10.2005
[ sulge aken ]