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Elulookirjeldus (CV)
1.Eesnimi Erkki
2.Perekonnanimi Juronen
3.Töökoht Tartu Ülikool, Üld-ja Molekulaarpatoloogia Instituut, Tartu 50411, Ravila 19
4.Ametikoht vanemteadur
5.Sünniaeg 24.02.1959 (päev.kuu.aasta)
6.Haridus Lõpetasin 1982 a. Tartu Ülikooli bioloogia osakonna ihtüoloogia-hüdrobioloogia eriala
7.Teenistuskäik 1982-1986 a. TÜ ÜMPI nooremteadur;
1986-1988 a. TÜ aspirantuur molekulaarbioloogia erialal;
1988-1993 a. TÜ ÜMPI immuunanalüüsi labori juhataja;
alates 1993 a. TÜ ÜMPI Inimese bioloogia ja geneetika õppetooli vanemteadur.
8.Teaduskraad bioloogia kandidaat molekulaarbioloogia erialal
9.Teaduskraadi välja
andnud asutus, aasta		 Tartu Ülikoolis 1988. a.
10.Tunnustused
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
12.Juhendamisel kaitstud
väitekirjad
13.Teadustöö põhisuunad Monoklonaalsed antikehad, immuunensümaatilised meetodid, geneetiliselt polümorfsed ensüümid, tüvirakud
14.Jooksvad grandid
15.Teaduspublikatsioonid

Zetterberg, M., Zetterberg, H., Palmér, M., Rymo, L., Blennow, K., Tasa, G., Juronen, E., Veromann, S., Teesalu, P., Karlsson, J-O. and Höglund K. (2004) Apolipoprotein E polymorphism in patients with cataract. Br J Ophthalmol . 88, 716-718.

Veromann, S., Sünter, A., Juronen, E., Tasa, G. and Panov, A. (2004) Eye lens crystallins: a component of intraocular pseudoexfoliative material. Ophthalmic Res. 36 (1), 51-54.

Wondimu, Z., Geberhiwot, T., Ingerpuu, S., Juronen, E., Xie, X., Lindbom, L., Doi, M., Kortesmaa, J., Thyboll, J., Tryggvason, K., Fadeel, B. and Patarroyo, M. (2004) An endothelial laminin isoform, laminin 8 ({alpha}4{beta}1{gamma}1), is secreted by blood neutrophils, promotes neutrophil migration and extravasation, and protects neutrophils from apoptosis. Blood 104(6), 1859-1866.

Veromann, S., Sünter, A., Tasa, G., Juronen, E., Panov, A., Pastak, M. and Kaljurand, K. (2003) Dietary sugar and salt represent real risk factors for cataract development. Ophthalmologica 217 (4), 302-307.

Yan, F-X., Ihnen, M.A., Langub, M.C., Hornung, C., Juronen, E., Rayens, M.-K., Wedlund, P.J. and Fanti, P. (2003) CYP2D6, GSTM1 and GSTT1 enzymes: Expression in parathyroid gland and association with parathyroid hormone level during early renal replacement therapy. Br. J. Clin. Pharmacology 56(1), 68-77.

Alexandrie, A.-K., Rannug, A., Juronen, E., Gunnar Tasa, G. and Warholm, M. (2002) Detection and characterization of a novel functional polymorphism in the GSTT1 gene. Pharmacogenetics 12 (8), 613-619.

Tasa, G., Kals, J., Muru, K., Juronen, E., Piirsoo, A., Veromann, S., Jänes, S., Mikelsaar, A.-V. and Lang, A. (2001) A novel mutation in M1S1 gene responsible for gelatinous drop-like corneal dystropy. Invest. Ophthalmol. Vis. Sci. 42, 2762-2764.

Juronen, E., Tasa G., Veromann, S., Parts, L., Tiidla, A., Pulges, R., Panov, A., Soovere, L., Koka, K. and Mikelsaar, A.-V. (2000) Polymorphic glutathione S-transferase M1 is a risk factor of primary open-angle glaucoma among Estonians. Exp. Eye Res. 71 (5), 447-452.

Juronen, E., Tasa G., Veromann, S., Parts, L., Tiidla, A., Pulges, R., Panov, A., Soovere, L., Koka, K. and Mikelsaar, A.-V. (2000) Polymorphic glutathione S-transferases as genetic risk factors for senile cortical cataract in Estonians. Invest. Ophthalmol. Vis. Sci. 41, 2262-2267.

Kurg, R., Parik, J., Juronen, E., Sedman, T., Abroi, A., Liiv, I., Langel, Ü. and Ustav, M. (1999) Effect of bovine papillomavirus E2 protein-specific monoclonal antibodies on papillomavirus DNA replication. J. Virol. 73 (6), 4670-4677.

Veitch, J.M., Murray, G.I., Juronen, E., Kilty, C.G., Doyle, S., Hawksworth, G.M. and Rodilla, V. (1997) Theta-class glutathione S-transferase in human kidney and renal tumors. Biochemical Society Transactions 25, 605.

Juronen, E., Tasa, G., Uusküla, M., Pooga, M. and Mikelsaar, A.-V. (1996) Producing and characterization of monoclonal antibodies against class Theta glutathione S-transferase T1-1. Hybridoma 15, 77-82.

Juronen, E., Tasa, G., Uusküla, M., Pooga, M. and Mikelsaar, A.-V. (1996) Purification, characterization and tissue distribution of human class Theta glutathione S-transferase T1-1. Biochem. Mol. Biol. Int. 39 (1), 21-29.

Tasa, G., Juronen, E., Viikmaa, M., Tiidla, A., Pärlist, P., Uusküla, M., Kalev, I. and Mikelsaar, A.-V. (1996) Distribution of glutathione S-transferase T1 phenotypes in the Estonian population. Gene Geography 10 (3), 181-189.

Tasa, G., Juronen, E., Uusküla, M., Viikmaa, M. and Mikelsaar, A.-V. (1995) Phenotyping of glutathione S-transferase M1 in Estonian population by ELISA using GSTM1a and GSTM1b specific monoclonal antibodies. Clin. Chim. Acta 239, 191-196.

Juronen, E., Tasa, G., Uusküla, M., Parik, J. and Mikelsaar, A.-V. (1994) Allele specific monoclonal antibodies against glutathione S-transferase Mu1-1. Hybridoma 13, 477-484.

Veromann, S., Sikut, R. and Juronen, E. (1994) No immunoglobulins in cataractous lenses. Ophtalmic Res. 26, 261-263.

Juronen, E., Parik, J. and Toomik, P. (1991) FPLC purification of mouse monoclonal antibodies from ascitic fluid using blue DEAE and thiophilic sorbents. J. Immunol. Methods 136, 103-109.

Lepner, U., Juronen, E. and Tamm, V. (1989) Myoglobin levels in patients with obliterating diseases of the lower extremities. Cardiologia 24 (4), 83-86, (in russ.).

Juronen, E., Viikmaa, M. and Mikelsaar. A.-V. (1988) Rapid, simple and sensitive antigen capture ELISA for the quantitation of myoglobin using monoclonal antibodies. J. Immunol. Methods 111, 109-115.

Juronen, E., Viikmaa, M. and Mikelsaar, A.-V. (1988) Use of monoclonal antibodies for quantitative estimation of myoglobin by means of solid phase immunoenzyme "sandwich" assay. Vopr. Med. Chimi 4, 132-136, (in russ.).

viimati muudetud: 26.07.2005

Curriculum Vitae (CV)
1.First Name Erkki
2.Surname Juronen
3.Institution University of Tartu, Institute of General and molecular Pathology, Tartu 50411, Ravila 19
4.Position senior scientist
5.Date of birth 24.02.1959 (day.month.year)
6.Education University of Tartu, Department of Biology, ichtyologist-hydrobiologist
7.Research and
professional experience		 1982-1986 junior scientist in University of Tartu, IGMP;
1986-1988 postgraduate student in molecular biology in University of Tartu;
1988-1993 head of Laboratory of Immunoanalysis in University of Tartu;
since 1993 senior scientist in University of Tartu, Institute of General and Molecular Pathology, Department of Human Biology and Genetics
8.Academic degree Canditate of biological science degree in molecular biology
9.Dates and sites of
earning the degrees		 1988 in University of Tartu
10.Honours/awards
11.Research-administrative
experience
12.Supervised dissertations
13.Current research program Monoclonal antibodies, immunoenzymatic methods, genetically polymorphic detoxifying enzymes, stem cells
14.Current grant funding
15.List of most important publications

Zetterberg, M., Zetterberg, H., Palmér, M., Rymo, L., Blennow, K., Tasa, G., Juronen, E., Veromann, S., Teesalu, P., Karlsson, J-O. and Höglund K. (2004) Apolipoprotein E polymorphism in patients with cataract. Br J Ophthalmol . 88, 716-718.

Veromann, S., Sünter, A., Juronen, E., Tasa, G. and Panov, A. (2004) Eye lens crystallins: a component of intraocular pseudoexfoliative material. Ophthalmic Res. 36 (1), 51-54.

Wondimu, Z., Geberhiwot, T., Ingerpuu, S., Juronen, E., Xie, X., Lindbom, L., Doi, M., Kortesmaa, J., Thyboll, J., Tryggvason, K., Fadeel, B. and Patarroyo, M. (2004) An endothelial laminin isoform, laminin 8 ({alpha}4{beta}1{gamma}1), is secreted by blood neutrophils, promotes neutrophil migration and extravasation, and protects neutrophils from apoptosis. Blood 104(6), 1859-1866.

Veromann, S., Sünter, A., Tasa, G., Juronen, E., Panov, A., Pastak, M. and Kaljurand, K. (2003) Dietary sugar and salt represent real risk factors for cataract development. Ophthalmologica 217 (4), 302-307.

Yan, F-X., Ihnen, M.A., Langub, M.C., Hornung, C., Juronen, E., Rayens, M.-K., Wedlund, P.J. and Fanti, P. (2003) CYP2D6, GSTM1 and GSTT1 enzymes: Expression in parathyroid gland and association with parathyroid hormone level during early renal replacement therapy. Br. J. Clin. Pharmacology 56(1), 68-77.

Alexandrie, A.-K., Rannug, A., Juronen, E., Gunnar Tasa, G. and Warholm, M. (2002) Detection and characterization of a novel functional polymorphism in the GSTT1 gene. Pharmacogenetics 12 (8), 613-619.

Tasa, G., Kals, J., Muru, K., Juronen, E., Piirsoo, A., Veromann, S., Jänes, S., Mikelsaar, A.-V. and Lang, A. (2001) A novel mutation in M1S1 gene responsible for gelatinous drop-like corneal dystropy. Invest. Ophthalmol. Vis. Sci. 42, 2762-2764.

Juronen, E., Tasa G., Veromann, S., Parts, L., Tiidla, A., Pulges, R., Panov, A., Soovere, L., Koka, K. and Mikelsaar, A.-V. (2000) Polymorphic glutathione S-transferase M1 is a risk factor of primary open-angle glaucoma among Estonians. Exp. Eye Res. 71 (5), 447-452.

Juronen, E., Tasa G., Veromann, S., Parts, L., Tiidla, A., Pulges, R., Panov, A., Soovere, L., Koka, K. and Mikelsaar, A.-V. (2000) Polymorphic glutathione S-transferases as genetic risk factors for senile cortical cataract in Estonians. Invest. Ophthalmol. Vis. Sci. 41, 2262-2267.

Kurg, R., Parik, J., Juronen, E., Sedman, T., Abroi, A., Liiv, I., Langel, Ü. and Ustav, M. (1999) Effect of bovine papillomavirus E2 protein-specific monoclonal antibodies on papillomavirus DNA replication. J. Virol. 73 (6), 4670-4677.

Veitch, J.M., Murray, G.I., Juronen, E., Kilty, C.G., Doyle, S., Hawksworth, G.M. and Rodilla, V. (1997) Theta-class glutathione S-transferase in human kidney and renal tumors. Biochemical Society Transactions 25, 605.

Juronen, E., Tasa, G., Uusküla, M., Pooga, M. and Mikelsaar, A.-V. (1996) Producing and characterization of monoclonal antibodies against class Theta glutathione S-transferase T1-1. Hybridoma 15, 77-82.

Juronen, E., Tasa, G., Uusküla, M., Pooga, M. and Mikelsaar, A.-V. (1996) Purification, characterization and tissue distribution of human class Theta glutathione S-transferase T1-1. Biochem. Mol. Biol. Int. 39 (1), 21-29.

Tasa, G., Juronen, E., Viikmaa, M., Tiidla, A., Pärlist, P., Uusküla, M., Kalev, I. and Mikelsaar, A.-V. (1996) Distribution of glutathione S-transferase T1 phenotypes in the Estonian population. Gene Geography 10 (3), 181-189.

Tasa, G., Juronen, E., Uusküla, M., Viikmaa, M. and Mikelsaar, A.-V. (1995) Phenotyping of glutathione S-transferase M1 in Estonian population by ELISA using GSTM1a and GSTM1b specific monoclonal antibodies. Clin. Chim. Acta 239, 191-196.

Juronen, E., Tasa, G., Uusküla, M., Parik, J. and Mikelsaar, A.-V. (1994) Allele specific monoclonal antibodies against glutathione S-transferase Mu1-1. Hybridoma 13, 477-484.

Veromann, S., Sikut, R. and Juronen, E. (1994) No immunoglobulins in cataractous lenses. Ophtalmic Res. 26, 261-263.

Juronen, E., Parik, J. and Toomik, P. (1991) FPLC purification of mouse monoclonal antibodies from ascitic fluid using blue DEAE and thiophilic sorbents. J. Immunol. Methods 136, 103-109.

Lepner, U., Juronen, E. and Tamm, V. (1989) Myoglobin levels in patients with obliterating diseases of the lower extremities. Cardiologia 24 (4), 83-86, (in russ.).

Juronen, E., Viikmaa, M. and Mikelsaar. A.-V. (1988) Rapid, simple and sensitive antigen capture ELISA for the quantitation of myoglobin using monoclonal antibodies. J. Immunol. Methods 111, 109-115.

Juronen, E., Viikmaa, M. and Mikelsaar, A.-V. (1988) Use of monoclonal antibodies for quantitative estimation of myoglobin by means of solid phase immunoenzyme "sandwich" assay. Vopr. Med. Chimi 4, 132-136, (in russ.).

last updated: 26.07.2005

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