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| Elulookirjeldus (CV) | ||
| 1. | Eesnimi | Tiit |
| 2. | Perekonnanimi | Land |
| 3. | Töökoht | Stockholmi Ülikooli Neurokeemia Instituut |
| 4. | Ametikoht | teadur |
| 5. | Sünniaeg | 25.09.1964 (päev.kuu.aasta) |
| 6. | Haridus | Tartu Ülikooli Füüsika-keemia teaduskond, 1989 |
| 7. | Teenistuskäik | 1990-1999 doktorant, Stockholmi Ülikool 1994-1999 teadur, USA Rahvuslik Tervise Ülikool (National Institute of Health) 1999-2005 teadur ja õppejõud; Stockholmi Ülikooli Neurokeemia ja Neurotoksikoloogia Instituut |
| 8. | Teaduskraad | filosoofiadoktor (Ph.D) |
| 9. | Teaduskraadi välja andnud asutus, aasta |
Stockholmi Ülikool, 1994 |
| 10. | Tunnustused | |
| 11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
Õppeprodekaan, Stockholmi Ülikooli Neurokeemia Instituut |
| 12. | Juhendamisel kaitstud väitekirjad |
|
| 13. | Teadustöö põhisuunad | 1.Beeta-amüloid prekursor valkude (APP) uute fragmentide signaali ülekande mehhanismid ja nende roll Alzheimeri tõves 2.Raua regulatsioon ja raua poolt indutseeritud oksüdatiivne stress prioonhaigustes 3.Raua roll Alzheimeri tõves |
| 14. | Jooksvad grandid | Swedish Fund For Research Without Animal Experiments |
| 15. | Teaduspublikatsioonid |
Fernaeus S, Halldin J, Bedecs K, Land T. Changed iron regulation in scrapie-infected neuroblastoma cells. Brain Res Mol Brain Res. 2005 Feb 18; 133(2):266-73. PMID:15710243 Fernaeus S, Land T. Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells. Neurosci Lett. 2005 Jul 15; 382(3):217-20. PMID:15925093 Karelson E, Fernaeus S, Reis K, Bogdanovic N, Land T. Stimulation of G-proteins in human control and Alzheimer's disease brain by FAD mutants of APP(714-723): implication of oxidative mechanisms. J Neurosci Res. 2005 Feb 1;79(3):368-74. PMID:15614786 Kilk K, Elmquist A, Saar K, Pooga M, Land T, Bartfai T, Soomets U, Langel U.Targeting of antisense PNA oligomers to humna galanin receptor type 1mRNA. Neuropeptides. 2004 Oct;316-24.PMID: 15464198 Mahlapuu R, Viht K, Balaspiri L, Bogdanovic N, Saar K, Soomets U, Land T, Zilmer M, Karelson E, Langel U. Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain. Brain res Mol Brain Res. 2003 Sep 10; 117(1):73-82. PMID:14499483 |
viimati muudetud: 08.08.2005
| Curriculum Vitae (CV) | ||
| 1. | First Name | Tiit |
| 2. | Surname | Land |
| 3. | Institution | Department of Neurochemistry, Stockholm University |
| 4. | Position | reseacher |
| 5. | Date of birth | 25.09.1964 (day.month.year) |
| 6. | Education | Faculty of Physics and Chemistry, Tartu University, 1989 |
| 7. | Research and professional experience |
1990-1999 doctorant, Stockholm University 1994-1999 researcher, National Institute of Health, USA 1999-2005 researcher/lecturer, Department Neurochemistry and Neurotoxicology, Stockholm Univrersity |
| 8. | Academic degree | Doctor Philosophy (Ph.D) |
| 9. | Dates and sites of earning the degrees |
Stockholm University, 1994 |
| 10. | Honours/awards | |
| 11. | Research-administrative experience |
Director of studies, Department of Neurochemistry, Stockholm University |
| 12. | Supervised dissertations | |
| 13. | Current research program | 1. Signal transduction mechanisms of novel fragments of beta-amyloid precursor protein (APP) and their role in Alzheimer's disease 2.Iron regulation and iron-induced oxidative stress in prion diseases 3.Role of iron in Alzheimer's disease |
| 14. | Current grant funding | Swedish Fund For Research Without Animal Experiments |
| 15. | List of most important publications |
Fernaeus S, Halldin J, Bedecs K, Land T. Changed iron regulation in scrapie-infected neuroblastoma cells. Brain Res Mol Brain Res. 2005 Feb 18; 133(2):266-73. PMID:15710243 Fernaeus S, Land T. Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells. Neurosci Lett. 2005 Jul 15; 382(3):217-20. PMID:15925093 Karelson E, Fernaeus S, Reis K, Bogdanovic N, Land T. Stimulation of G-proteins in human control and Alzheimer's disease brain by FAD mutants of APP(714-723): implication of oxidative mechanisms. J Neurosci Res. 2005 Feb 1;79(3):368-74. PMID:15614786 Kilk K, Elmquist A, Saar K, Pooga M, Land T, Bartfai T, Soomets U, Langel U.Targeting of antisense PNA oligomers to humna galanin receptor type 1mRNA. Neuropeptides. 2004 Oct;316-24.PMID: 15464198 Mahlapuu R, Viht K, Balaspiri L, Bogdanovic N, Saar K, Soomets U, Land T, Zilmer M, Karelson E, Langel U. Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain. Brain res Mol Brain Res. 2003 Sep 10; 117(1):73-82. PMID:14499483 |
last updated: 08.08.2005
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