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Elulookirjeldus (CV)
1.Eesnimi Meeri
2.Perekonnanimi Sassian
3.Töökoht Orgaanilise ja bioorgaanilise keemia instituut, Tartu Ülikool
4.Ametikoht Teadur
5.Sünniaeg 23.12.1973 (päev.kuu.aasta)
6.Haridus 1992-1996 Tartu Ülikooli keemiaosakonna üliõpilane,
B.Sc.(keemia) 1996
1996-1999 Tartu Ülikooli keemiaosakonna magistrant,
1998-1999 õpetajakoolitus Tartu Ülikoolis,
õpetaja kutsetunnistus 1999.
1999-2003 Tartu Ülikooli keemiaosakonna doktorant
2003-2004 järeldoktorantuur Stockholmi Ülikooli neurokeemia ja
neurotoksikoloogia instituudis
7.Teenistuskäik 2003-2004 Tartu Ülikool, orgaanilise ja bioorgaanilise keemia
instituut, erakorraline teadur
2005- Tartu Ülikool, orgaanilise ja bioorgaanilise keemia
instituut, teadur
8.Teaduskraad Teadusmagister (keemia);
PhD (keemia)
9.Teaduskraadi välja
andnud asutus, aasta		 Tartu Ülikool, 1999;
Tartu Ülikool, 2003
10.Tunnustused -
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus		 Avatud ülikooli orgaanilise keemia õppe kuraator;
Eesti Biokeemia Seltsi liige
12.Juhendamisel kaitstud
väitekirjad
13.Teadustöö põhisuunad Orgaaniline süntees, Grignard'i reaktsiooni mehhanism, peptiidsüntees, biomimeetikute konstrueerimine ja süntees
14.Jooksvad grandid SF0182592s03, Biomimeetikute konstrueerimine, keemiline süntees ja bioloogilise aktiivsuse uurimine, teadur
15.Teaduspublikatsioonid

M. E. Lindgren, K. Rosenthal-Aizman, E. Eiríksdóttir, Y. Jiang, M. Sassian, P. Östlund, M. Hällbrink, Ü. Langel. Overcoming methotrexate resistance in breast cancer tumor cells by the use of a new cell-penetrating peptide. Accepted for publication in Biochemical Pharmacology

Saar, K., Lindgren, M., Hansen, M., Eiríksdottír, E., Jian Y., Rosenthal-Aizman, K., Sassian, M. and Langel Ü. Cell-Penetrating Peptides: A Comparative Membrane Toxicity Study. Analytical Biochemistry 2005, 345, 55-65.

Jiang, J., Sassian, M., Langel, Ü. Synthesis and Applications of Cell-Penetrating Peptide-PNA conjugate. Chimica Oggi/Chemistry Today 2004 22 (7/8), 14-17.

Jiang, J., Sassian, M., Langel, Ü. Synthesis and Applications of Cell-Penetrating Peptide-PNA conjugate. Chimica Oggi/Chemistry Today 2004 22 (7/8), 14-17.

Tuulmets,A., D. Panov and M. Sassian On the Mechanism Derived from Kinetic Solvent Effects of Grignard Reactions with Silanes. Tetrahedron Lett, 2003, 3943-3945

Tuulmets A, Nguyen BT, Panov D, Sassian M, Järv J.Kinetics of the grignard reaction with silanes in diethyl ether and ether-toluene mixtures. J Org Chem. 2003 Dec 26;68(26):9933-7

M. Sassian and A. Tuulmets Reactions of partially solvated Grignard reagents with benzaldehyde. Main Group Metal Chem. 2002, 25, 745-748.

M. Sassian, D. Panov, A. Tuulmets Grignard reagents in toluene solution. Appl. Organomet. Chem. 2002, 16, 525-529.

A. Tuulmets, M. Sassian Reactions of Partially Solvated Grignard Reagents with a Ketone. J. Organomet. Chem. 1999, 586, 145-149.

viimati muudetud: 10.10.2005

Curriculum Vitae (CV)
1.First Name Meeri
2.Surname Sassian
3.Institution Institute of Organic and Bioorganic Chemistry, University of Tartu
4.Position Researcher
5.Date of birth 23.12.1973 (day.month.year)
6.Education 1992-1996 University of Tartu, Department of Chemistry,
B.Sc. (chemistry) 1996
1996-1999 University of Tartu, Department of Chemistry,
1998-1999 Teacher education program in University of Tartu,
certificate of the qualification of
chemistry teacher 1999.
1999-2003 University of Tartu, Department of Chemistry,
doctoral studies
2003-2004 Department of Neurochemistry and Neurotoxicology,
Stockholm University. Post doctoral studies.
7.Research and
professional experience		 2003-2004 University of Tartu, Faculty of Physics and Chemistry,
Institute of Organic and Bioorganic Chemistry,
Research Assistant
2005- University of Tartu, Researcher
8.Academic degree Master of Sciences (Chem.);
PhD, chemistry
9.Dates and sites of
earning the degrees		 University of Tartu, 1999;
University of Tartu, 2003
10.Honours/awards -
11.Research-administrative
experience		 Coordinator, Open University Organic Chemistry Courses;
Member, Estonian Biochemical Society
12.Supervised dissertations
13.Current research program Organic synthesis, Grignard reaction mechanism, peptide synthesis, design and synthesis of biomimetic molecules
14.Current grant funding SF0182592s03, Design, chemical synthesis and bioactivity of biomimetic molecules, researcher
15.List of most important publications

M. E. Lindgren, K. Rosenthal-Aizman, E. Eiríksdóttir, Y. Jiang, M. Sassian, P. Östlund, M. Hällbrink, Ü. Langel. Overcoming methotrexate resistance in breast cancer tumor cells by the use of a new cell-penetrating peptide. Accepted for publication in Biochemical Pharmacology

Saar, K., Lindgren, M., Hansen, M., Eiríksdottír, E., Jian Y., Rosenthal-Aizman, K., Sassian, M. and Langel Ü. Cell-Penetrating Peptides: A Comparative Membrane Toxicity Study. Analytical Biochemistry 2005, 345, 55-65.

Jiang, J., Sassian, M., Langel, Ü. Synthesis and Applications of Cell-Penetrating Peptide-PNA conjugate. Chimica Oggi/Chemistry Today 2004 22 (7/8), 14-17.

Jiang, J., Sassian, M., Langel, Ü. Synthesis and Applications of Cell-Penetrating Peptide-PNA conjugate. Chimica Oggi/Chemistry Today 2004 22 (7/8), 14-17.

Tuulmets,A., D. Panov and M. Sassian On the Mechanism Derived from Kinetic Solvent Effects of Grignard Reactions with Silanes. Tetrahedron Lett, 2003, 3943-3945

Tuulmets A, Nguyen BT, Panov D, Sassian M, Järv J.Kinetics of the grignard reaction with silanes in diethyl ether and ether-toluene mixtures. J Org Chem. 2003 Dec 26;68(26):9933-7

M. Sassian and A. Tuulmets Reactions of partially solvated Grignard reagents with benzaldehyde. Main Group Metal Chem. 2002, 25, 745-748.

M. Sassian, D. Panov, A. Tuulmets Grignard reagents in toluene solution. Appl. Organomet. Chem. 2002, 16, 525-529.

A. Tuulmets, M. Sassian Reactions of Partially Solvated Grignard Reagents with a Ketone. J. Organomet. Chem. 1999, 586, 145-149.

last updated: 10.10.2005

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