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| Elulookirjeldus (CV) | ||
| 1. | Eesnimi | Kai |
| 2. | Perekonnanimi | Kisand |
| 3. | Töökoht | Tartu Ülikooli arstiteaduskonna üld- ja molekulaarpatoloogia instituut |
| 4. | Ametikoht | erakorraline vanemteadur |
| 5. | Sünniaeg | 08.03.1965 (päev.kuu.aasta) |
| 6. | Haridus | Tartu 2. Keskkool, 1983 Tartu Ülikool, diplom ravi erialal (cum laude) (1989) 1992-1998 Tartu Ülikool, doktorantuur immunoloogia erialal Tartu Ülikool, meditsiinidoktor, 1999 |
| 7. | Teenistuskäik | 1989 TÜ ÜMPI vanemlaborant 1999-2000 -TÜ ÜMPI immunoloogia teadur 2001-2002 -TÜ Farmakoloogia instituut, erakorraline vanemteadur (järeldoktorantuur) 2003 - 2004 TÜ ÜMPI immunoloogia teadur 2004 - 2005 Uppsala Ülikooli Autoimmuniteedi ja Poletiku Keskus, järeldoktorantuur 2005 - TÜ ÜMPI erakorraline vanemteadur |
| 8. | Teaduskraad | Meditsiinidoktor |
| 9. | Teaduskraadi välja andnud asutus, aasta |
Tartu Ülikool, 1999 |
| 10. | Tunnustused | |
| 11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
Konverentside orgkomiteede liige: International Course "Autoimmunity: Basic and Clinical" (1994) International Course "Autoimmunity: Molecular and Clinical Aspects" (2001) Eesti immunoloogide seltsi liige Balti immunoloogide seltsi liige Eesti immunoloogide ja allergoloogide seltsi esimees (alates 2001) |
| 12. | Juhendamisel kaitstud väitekirjad |
Mai Vaht, MSc, 2004, juh. Kai Kisand, Ulle Kikas. Looduslik ultraviolettkiirgus Pärnu rannas ja selle moju päevitajate lumfotsuutide alaklassidele. Tartu Ulikool |
| 13. | Teadustöö põhisuunad | 1. Mitokondrite vastased autoantikehad primaarse biliaarse tsiroosi koorral: diagnostiline, prognostiline ja patogeneetiline tähendus. 2. Autoantikehade toime elusrakkudele. 3. Puukborrelioosi eri haigusvormide (sealhulgas neuroborrelioosi) kliinilise kulu patogeneetilised ja immuunaspektid. Seroloogilise diagnostika iseärasused. Rakuline immuunsus borrelioosi erinevate vormide korral 4. Downi sündroomiga patsientide rakulise immuunsuse iseärasused. Immuunpuudulikkuse ja autoimmuunsete reaktsioonide seostamine rakulise immuunsuse näitajatega. 5. Autoimmuunse regulaatori AIRE ekspressioon erinevates dendriitrakkudes ja selle funktsiooni selgitamine perifeerses immuunsüsteemis. |
| 14. | Jooksvad grandid | ETF 6514 Tsöliaakia ja diabeedi korral esinevate limaskesta muutuste ning kaasnevate immunoloo´giiste häirete uuring |
| 15. | Teaduspublikatsioonid |
L.Kadaja, K.E.Kisand, N.Peet, U.Braun, K.Metsküla, K.Teesalu, R.Vibo, K.V.Kisand, R.Uibo, H.Jockusch, E.K.Seppet. IgG from patients with liver diseases inhibit mitochondrial respiration in permeabilized oxidative muscle cells: Impaired function of intracellular energetic units? Mol Cell. Biochem (2004) 256/257:291-303. K.E.Kisand, M.Utt, K.V.Kisand, T.Prükk, R.Uibo. Serological description of Estonian patients with Lyme disease, a comparison with control sera from endemic and non-endemic areas. Int J Med Microbiol (2003) Suppl 37:174-178. KE.Kisand, K.Metsküla, KV.Kisand, T.Kivik, ME.Gershwin, R.Uibo. The follow-up of asymptomatic persons with antibodies to pyruvate dehydrogenase in adult population samples. J Gastroenterol (2001) 36:248-54. Kisand KE, Kisand KV, Karvonen A-L, Vuoristo M, Mattila J, Mäkinen J, Uibo R. Antibodies to pyruvate dehydrogenase in primary biliary cirrhosis: correlation with histology. APMIS 1998; 106: 884-892. Kisand KE, Kisand KV, Vuoristo M, Mattila J, Mäkinen J, Salupere V, Uibo R. Comparison of ELISA test and PDH inhibition assay in description of different populations of patients with primary biliary cirrhosis. Central-European Journal of Immunology 1998; 23: 203-207 Kisand K, Karvonen A-L, Vuoristo M, Färkkilä M, Lehtola J, Inkovaara J, Kisand K, Miettinen T, Krohn K, Uibo R. Ursodeoxycholic acid treatment lowers the serum level of antibodies against pyruvate dehydrogenase and influences their inhibitory capacity for the enzyme complex in patients with primary biliary cirrhosis. J Mol Med 1996; 74: 269 - 274 Kisand K, Kisand K, Salupere V, Uibo R. Enzyme-linked immunosorbent assays for the determination of IgG, IgA and IgM autoantibodies to pyruvate dehydrogenase in primary biliary cirrhosis. Intern J Clin Lab Res 1994; 24: 98-101. |
viimati muudetud: 09.08.2005
| Curriculum Vitae (CV) | ||
| 1. | First Name | Kai |
| 2. | Surname | Kisand |
| 3. | Institution | Institute of General and Molecular Pathology, Medical Faculty, University of Tartu |
| 4. | Position | senior research fellow (extraordinaria) |
| 5. | Date of birth | 08.03.1965 (day.month.year) |
| 6. | Education | Tartu Secondary School No. 2, 1983 University of Tartu, Medical Faculty,1989 University of Tartu, PhD, 1999 |
| 7. | Research and professional experience |
1999 - 2000 research fellow in Institute of General and Molecular Pathology, University of Tartu 2001 - 2002 postdoc in Institute of Pharmacology, University of Tartu 2003 - 2004 research fellow in Institute of General and Molecular Pathology, University of Tartu 2004 - 2005 postdoc in Center of Autoimmunity and Inflammation, Univesity of Uppsala |
| 8. | Academic degree | PhD |
| 9. | Dates and sites of earning the degrees |
University of Tartu, 1999 |
| 10. | Honours/awards | |
| 11. | Research-administrative experience |
Member of organising committees: International Course "Autoimmunity: Basic and Clinical" (1994) International Course "Autoimmunity: Molecular and Clinical Aspects" (2001) Member of Estonian Society of Immunology Member of Baltic Association of immunological Societies President of Estonian Society of Immunology and Allergology |
| 12. | Supervised dissertations |
Mai Vaht, MSc, 2004, superv. Kai Kisand, Ulle Kikas. Looduslik ultraviolettkiirgus Pärnu rannas ja selle moju päevitajate lumfotsuutide alaklassidele. Tartu Ulikool |
| 13. | Current research program | 1. Mitochondrial autoantibodies in primary biliary cirrhosis: diagnostic, prognostic and pathogenetic significance. 2. The influence of autoantibodies on living cells. 3. The immunologic characteristics of different forms of Lyme borreliosis. 4. Cellular immunity in Down's syndrome. 5. AIRE expression in dendritic cells |
| 14. | Current grant funding | 6514 |
| 15. | List of most important publications |
L.Kadaja, K.E.Kisand, N.Peet, U.Braun, K.Metsküla, K.Teesalu, R.Vibo, K.V.Kisand, R.Uibo, H.Jockusch, E.K.Seppet. IgG from patients with liver diseases inhibit mitochondrial respiration in permeabilized oxidative muscle cells: Impaired function of intracellular energetic units? Mol Cell. Biochem (2004) 256/257:291-303. K.E.Kisand, M.Utt, K.V.Kisand, T.Prükk, R.Uibo. Serological description of Estonian patients with Lyme disease, a comparison with control sera from endemic and non-endemic areas. Int J Med Microbiol (2003) Suppl 37:174-178. KE.Kisand, K.Metsküla, KV.Kisand, T.Kivik, ME.Gershwin, R.Uibo. The follow-up of asymptomatic persons with antibodies to pyruvate dehydrogenase in adult population samples. J Gastroenterol (2001) 36:248-54. Kisand KE, Kisand KV, Karvonen A-L, Vuoristo M, Mattila J, Mäkinen J, Uibo R. Antibodies to pyruvate dehydrogenase in primary biliary cirrhosis: correlation with histology. APMIS 1998; 106: 884-892. Kisand KE, Kisand KV, Vuoristo M, Mattila J, Mäkinen J, Salupere V, Uibo R. Comparison of ELISA test and PDH inhibition assay in description of different populations of patients with primary biliary cirrhosis. Central-European Journal of Immunology 1998; 23: 203-207 Kisand K, Karvonen A-L, Vuoristo M, Färkkilä M, Lehtola J, Inkovaara J, Kisand K, Miettinen T, Krohn K, Uibo R. Ursodeoxycholic acid treatment lowers the serum level of antibodies against pyruvate dehydrogenase and influences their inhibitory capacity for the enzyme complex in patients with primary biliary cirrhosis. J Mol Med 1996; 74: 269 - 274 Kisand K, Kisand K, Salupere V, Uibo R. Enzyme-linked immunosorbent assays for the determination of IgG, IgA and IgM autoantibodies to pyruvate dehydrogenase in primary biliary cirrhosis. Intern J Clin Lab Res 1994; 24: 98-101. |
last updated: 09.08.2005
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