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Elulookirjeldus (CV)
1.Eesnimi Tõnu
2.Perekonnanimi Kesvatera
3.Töökoht Keeemilise ja Bioloogilise Füüsika Instituut (KBFI)
4.Ametikoht vanemteadur
5.Sünniaeg 31.03.1952 (päev.kuu.aasta)
6.Haridus Tartu Ülikool, keemiaosakond, 1975
7.Teenistuskäik Küberneetika Instituut, nooremteadur, 1975-1980;
Keemil. Biol. Füüsika Instituut (KBFI), teadur, 1980-1984;
KBFI, vanemteadur, 1984-2005;
Lundi Ülikool, külalisteadlasena 3-6 kuud aastas, 1993-2005
8.Teaduskraad keemiakandidaat
9.Teaduskraadi välja
andnud asutus, aasta		 Keemia Instituut 1981
10.Tunnustused George Sorosi (Rahvusvahelise Teadusfondi) Stipendium, 1993; Stipendium Kuninglikult Rootsi Teaduste Akadeemialt (KVA) 1995; Stipendium Rootsi Loodusuuringute Nõukogult (NFR) 1996. a.
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus		 1988-2004, Eesti Biokeemia Seltsi (EBS) teadussekretär;
1997-2004, ETF grandihoidja, Grandid 2923, 4922;
Alates 2005, KBFI laborijuhataja asetäitja;
12.Juhendamisel kaitstud
väitekirjad
13.Teadustöö põhisuunad Elektrostaatilised interaktsioonid valkudes
14.Jooksvad grandid
15.Teaduspublikatsioonid

André, I., Kesvatera, T., Jönsson, B., and Linse, S. (2005) Salt Enhances Calmodulin-target Interaction. Biophys J, MS ID#: BIOPHYSJ/2005/068718

André, I., Kesvatera, T., Jönsson, B., Åkerfeldt, K., and Linse, S. (2004) The Role of Electrostatic Interactions in Calmodulin-Peptide Complex Formation. Biophys J, 87(3), 1929-1938

André, I., Kesvatera, T., Jönsson, B., & Linse, S. (2002) Electrostatic Contributions to Calmodulin Target Recognition. Protein Science, Vol 11, Suppl. 1, p.181-182.

Kesvatera, T., Jönsson, B., Thulin, E., Linse, S. Electrostatic optimization of calbindin D9k for calcium binding. Abstr Pap Am Chem Soc 223, 358 – PHYS Part 2 April 7 2002.

Kesvatera, T., Jönsson, B., Telling, A., Tõugu, V., Vija, H., Thulin, E., & Linse, S. (2001) Calbindin D9k: A Protein Optimized for Calcium Binding at Neutral pH. Biochemistry, 40(50), 15334-15340.

Kesvatera, T., Jönsson, B., Thulin, E., & Linse, S. (2001) Focusing of the Electrostatic Potential at EF-Hands of Calbindin D9k: Titration of Acidic Residues. PROTEINS: Structure, Function, and Genetics, 45(2), 129-135 .

Tõugu, V., & Kesvatera, T. (2001) Comparison of Salt Effects on the Reactions of Acetylcholinesterase with Cationic and Anionic Inhibitors. Biochim. Biophys. Acta, 1544(1-2),189-195.

Kesvatera, T., Jönsson, B., Thulin, E., & Linse, S. (1999) Ionization Behavior of Acidic Residues in Calbindin D9k, PROTEINS: Structure, Function, and Genetics, 37(1), 106-115.

Kesvatera, T., Jönsson, B., Thulin, E., & Linse, S. (1996) Measurement and Modelling of Sequence-Specific pKa Values of Lysine Residues in Calbindin D9k, J. Mol. Biol., 259(4), 828 - 839.

Tõugu, V., & Kesvatera, T. (1996) Role of Ionic Interactions in Cholinesterase Catalysis. Review, Biochim. Biophys. Acta, 1298(1), 12-30.

Saks V.A., Kuznetsov A.V., Khuchua Z.A., Vasilyeva E.V., Belikova Y.O., Kesvatera T., & Tiivel T. (1995) Control of Cellular Respiration in vivo by Mitochondrial Outer Membrane and by Creatine Kinase, J. Mol. Cell. Cardiol., 27, 625-645.

Kesvatera T., Jönsson B., Thulin E., & Linse S. (1994) Binding of Ca2+ to Calbindin D9k: Structural Stability and Function at High Salt Concentration, Biochemistry, 33(47), 14170-14176.

Tõugu V., Tiivel T., Talts P., Šikšnis V., Poyarkova S., Kesvatera T., & Aaviksaar A. (1994) Electrostatic Effects in Trypsin Reactions. Influence of Salts, Eur. J. Biochem., 222(2), 475 - 481.

viimati muudetud: 10.08.2005

Curriculum Vitae (CV)
1.First Name Tõnu
2.Surname Kesvatera
3.Institution National Institute of Chemical Physics and Biophysics (NICPB)
4.Position senior reserch scientist
5.Date of birth 31.03.1952 (day.month.year)
6.Education Tartu University, Department of Chemistry, 1975
7.Research and
professional experience		 Institite of Cybernetics, junior scientist, 1975-1980;
Institute of Chemical Physics and Biophysics, scientist, 1980-1984; National Institute of Chemical Physics and Biophysics, senior scientist, 1984-2005;
Lund University, visiting scientist 3-6 months a year, 1993-2005
8.Academic degree PhD
9.Dates and sites of
earning the degrees		 Institute of Chemistry, 1981
10.Honours/awards George Soros Award, 1993;
Scholarship from Royal Swedish Academy of Sciences (KVA), 1995;
Scholarship from The Swedish Natural Science Council (NFR), 1996;
11.Research-administrative
experience		 1988-2005 Secretary of the Estonian Biochemical Society;
1997-2004 PI for Grants 2923 and 4922 from Estonian Science Foundation;
Since 2005 deputy head of laboratory
12.Supervised dissertations
13.Current research program Electrostatic interactions in proteins
14.Current grant funding
15.List of most important publications

André, I., Kesvatera, T., Jönsson, B., and Linse, S. (2005) Salt Enhances Calmodulin-target Interaction. Biophys J, MS ID#: BIOPHYSJ/2005/068718

André, I., Kesvatera, T., Jönsson, B., Åkerfeldt, K., and Linse, S. (2004) The Role of Electrostatic Interactions in Calmodulin-Peptide Complex Formation. Biophys J, 87(3), 1929-1938

André, I., Kesvatera, T., Jönsson, B., & Linse, S. (2002) Electrostatic Contributions to Calmodulin Target Recognition. Protein Science, Vol 11, Suppl. 1, p.181-182.

Kesvatera, T., Jönsson, B., Thulin, E., Linse, S. Electrostatic optimization of calbindin D9k for calcium binding. Abstr Pap Am Chem Soc 223, 358 – PHYS Part 2 April 7 2002.

Kesvatera, T., Jönsson, B., Telling, A., Tõugu, V., Vija, H., Thulin, E., & Linse, S. (2001) Calbindin D9k: A Protein Optimized for Calcium Binding at Neutral pH. Biochemistry, 40(50), 15334-15340.

Kesvatera, T., Jönsson, B., Thulin, E., & Linse, S. (2001) Focusing of the Electrostatic Potential at EF-Hands of Calbindin D9k: Titration of Acidic Residues. PROTEINS: Structure, Function, and Genetics, 45(2), 129-135 .

Tõugu, V., & Kesvatera, T. (2001) Comparison of Salt Effects on the Reactions of Acetylcholinesterase with Cationic and Anionic Inhibitors. Biochim. Biophys. Acta, 1544(1-2),189-195.

Kesvatera, T., Jönsson, B., Thulin, E., & Linse, S. (1999) Ionization Behavior of Acidic Residues in Calbindin D9k, PROTEINS: Structure, Function, and Genetics, 37(1), 106-115.

Kesvatera, T., Jönsson, B., Thulin, E., & Linse, S. (1996) Measurement and Modelling of Sequence-Specific pKa Values of Lysine Residues in Calbindin D9k, J. Mol. Biol., 259(4), 828 - 839.

Tõugu, V., & Kesvatera, T. (1996) Role of Ionic Interactions in Cholinesterase Catalysis. Review, Biochim. Biophys. Acta, 1298(1), 12-30.

Saks V.A., Kuznetsov A.V., Khuchua Z.A., Vasilyeva E.V., Belikova Y.O., Kesvatera T., & Tiivel T. (1995) Control of Cellular Respiration in vivo by Mitochondrial Outer Membrane and by Creatine Kinase, J. Mol. Cell. Cardiol., 27, 625-645.

Kesvatera T., Jönsson B., Thulin E., & Linse S. (1994) Binding of Ca2+ to Calbindin D9k: Structural Stability and Function at High Salt Concentration, Biochemistry, 33(47), 14170-14176.

Tõugu V., Tiivel T., Talts P., Šikšnis V., Poyarkova S., Kesvatera T., & Aaviksaar A. (1994) Electrostatic Effects in Trypsin Reactions. Influence of Salts, Eur. J. Biochem., 222(2), 475 - 481.

last updated: 10.08.2005

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