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Elulookirjeldus (CV)
1.Eesnimi Maido
2.Perekonnanimi Remm
3.Töökoht Tartu Ülikool
4.Ametikoht korraline professor
5.Sünniaeg 11.07.1965 (päev.kuu.aasta)
6.Haridus Tartu Ülikool 1983-1990, bioloogia-geograafia teaduskond, biokeemia eriala.
7.Teenistuskäik 1990 - 1992 teadur, Eesti Biokeskus
1992 - 1997 doktorant, Tartu Ülikool
1997 – 1998 Postdoc, Uppsala University, Department of Molecular Biology
1999 – 2000 Postdoc, Karolinska Institute, Center for Genomics and Bioinformatics Research
2001 - ... Bioinformaatika grupi juht, Eesti Biokeskus
2003 - ...Bioinformaatika õppetooli korraline professor, TÜ MRI
8.Teaduskraad PhD
9.Teaduskraadi välja
andnud asutus, aasta
Tartu Ülikool, 1997
10.Tunnustused EC DG Research projekti Genemill repatrieerumise grant
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
- Seminaride korraldamine TÜ MRIs alates aastast 1995
- Artiklite peer review läbiviimine ajakirjades Bioinformatics, HumanMutation, Trends in Biotechnology ja BioSilico alates aastast 1999
- 24 töökohaga Linux-põhise arvutiklassi loomine ja ühendamine Eesti GRIDiga
- 7nda iga-aastase Põhjamaade Bioinformaatika konverentsi Bioinformatics2005 peakorraldaja (23 esinejat ja ca 200 osalejat, peamiselt välisriikidest).
- Eesti esindaja Põhjamaade Bioinformaatika ühingu juhatuses.
- Eesti HTM juures asuva Teaduskompetentsi nõukogu ekspertliige.
12.Juhendamisel kaitstud
väitekirjad

Reidar Andreson, MSc, 2005, juh. Maido Remm. Comparison of different in silico methods for improvement of PCR primer quality.. Tartu

13.Teadustöö põhisuunad Praimerite ja mikrokiipide disain. Assotsiatsiooniuuringutega seotud arvutusmetoodika ja algoritmide arendamine.
Ortoloogide detekteerimise meetodid eukarüootsetes genoomides.
14.Jooksvad grandid - Sihtfinantseerimisgrant (2004-2008). Inimese genoomi haplotüüpse struktuuri analüüs.
- ETF grant (2005-2006). Konserveerunud järjestuselementide detekteerimine eukarüootsetes genoomides võrdleva genoomika abil.
- EAS rakendusuuringu grant (2005-2007). DNA-DNA interaktsioonide modelleerimine.
- EU CRAFT grant (2005-2007). Array-SBS: uudsete mikrokiibi tehnoloogiate arendamine resekveneeriseks.
15.Teaduspublikatsioonid

Mägi R, Kaplinski L and Remm M (2006) The Whole Genome TagSNP Selection and Transferability Among HapMap Populations. Pacific Symposium of Biocomputing 2006, 535-543.

Kaplinski L, Andreson R, Puurand T and Remm M (2005) MultiPLX: automatic grouping and evaluation of PCR primers. Bioinformatics, 21:1701-1702.

Laan M, Wiebe V, Khusnutdinova E, Remm M, Pääbo S (2005) X-chromosome as a marker for population history: linkage disequilibrium and haplotype study in Eurasian populations. Eur. J Hum Gen 13: 452-462.

Mueller JC, Lõhmussaar E, Mägi R, Remm M, Bettecken T, Lichtner P, Huber S, Illig T, Luedemann J, Schreiber S, Wichmann HE, Pramstaller P, Romeo G, Testa A, Metspalu A and Meitinger T (2005) Comparative analysis of linkage disequilibrium patterns and tagSNP transferability among European populations and HapMap CEPH trios. Am J Hum Genet 76: 387-398.

O'Brien K, Remm M, Sonnhammer E (2005) Inparanoid: The eukaryotic ortholog database. Nucl. Acids Res. 2005 33: D476-D480.

Remm M, Kurg A, Metspalu A (2003)PCR and arrayed primer extension (APEX) for genome-wide linkage disequilibrium (LD) and haplotype mapping. In PCR Technology: Current Innovations ed. HG. Griffin and A. Griffin, CRC Press

Dawson E, Abecasis GR, Bumpstead S, Chen Y, Hunt S, Beare DM, Pabial J, Dibling T, Tinsley E, Kirby S, Carter D, Papaspyridonos M, Livingstone S, Ganske R, Lõhmussaar E, Zernant J, Tõnisson N, Remm M, Mägi R, Puurand T, Vilo J, Kurg A, Rice K, Deloukas P, Mott R, Metspalu A, Bentley DR, Cardon LR, Dunham I (2002)A first generation haplotype map of human chromosome 22. Nature, 418: 544-548

Remm M, Metspalu A (2002)High-density genotyping and linkage disequilibrium in the human genome using chromosome 22 as a model.Current Opinion in Chemical Biology 6: 24-30

Remm M, Storm C, Sonnhammer E (2001)Automatic clustering of orthologs and in-paralogs from pairwise species comparisons. J Mol Biol 314: 1041-1052

Remm M, Sonnhammer E (2000) Classification of transmembrane protein families in the Caenorhabditis elegans genome and identification of human orthologs.Genome Res 10: 1679-1689

Remm M, Remm A, Ustav M (1999) Human papillomavirus type 18 E1 protein is translated from polycistronic mRNA by a discontinuous scanning mechanism.J Virol 73: 3062-3070

Plumpton M, Sharp NA, Liddicoat LH, Remm M, Tucker DO, Hughes FJ, Russell SM, Romanos MA (1995)A high capacity assay for inhibitors of human papillomavirus DNA replication.Biotechnology (NY) 13: 1210-1214

Remm M, Brain R, Jenkins JR (1992)The E2 binding sites determine the efficiency of replication for the origin of human papillomavirus type 18.Nucleic Acids Res 20: 6015-6021

Sturzbecher HW, Brain R, Addison C, Rudge K, Remm M, Grimaldi M, Keenan E, Jenkins JR (1992)A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization.Oncogene 7: 1513-23

viimati muudetud: 26.01.2006

Curriculum Vitae (CV)
1.First Name Maido
2.Surname Remm
3.Institution University of Tartu
4.Position full professor
5.Date of birth 11.07.1965 (day.month.year)
6.Education University of Tartu 1983-1990, Faculty of Biology and Geography, graduated as biochemist.
7.Research and
professional experience
1990 - 1992 Research Scientist, Estonian Biocentre
1992 – 1997 Ph.D. Student, University of Tartu, ESTONIA
1997 – 1998 Postdoc training, Uppsala University, Department of Molecular Biology, Bioinformatics group, SWEDEN
1999 – 2000 Postdoc training, Karolinska Institute, Center for Genomics and Bioinformatics Research, SWEDEN
2001 - ... Bioinformatics Group Leader, Estonian Biocentre, ESTONIA
2003 - ... Professor, Head of the Chair of Bioinformatics, University of Tartu, Estonia
8.Academic degree PhD
9.Dates and sites of
earning the degrees
University of Tartu, 1997
10.Honours/awards EC project Genemill repatriation grant
11.Research-administrative
experience
- Seminar organization since 1995
- Peer review of papers for journals Bioinformatics, Human Mutation, Trends in Biotechnology and BioSilico
- Installation of Linux based computer class and joining it with the Estonian GRID project
- Main organizer for the 7th annual Nordic Bioinformatics conference Bioinformatics2005 in Tartu (23 speakers, ca 200 participants, mostly from outside Estonia).
- Representative of Estonia in board of Nordic Society of Bioinformatics.
- Member of expert comission of Scientific Competence at Estonian Ministry of Education and Research.
12.Supervised dissertations

Reidar Andreson, MSc, 2005, superv. Maido Remm. Comparison of different in silico methods for improvement of PCR primer quality.. Tartu

13.Current research program Design of primers and oligos for microarrays.
Method and algorithm development for large scale association studies.
Ortholog detection methods for eukaryotic genomes.
14.Current grant funding - Haplotype structure of the human genome - core grant from the Ministry of Education and Research - 2004 - 2008.
- Grant from Estonian Science Foundation (2005-2006). Detection of conserved sequence motifs in eukaryotic genomes using comparative genomics approach.
- Applied Research Grant from Enterprise Estonia (2005-2007). Modeling of DNA-DNA interactions.
- EU CRAFT grant Array-SBS (2005-2007). Development of novel microarrays for resequencing.
15.List of most important publications

Mägi R, Kaplinski L and Remm M (2006) The Whole Genome TagSNP Selection and Transferability Among HapMap Populations. Pacific Symposium of Biocomputing 2006, 535-543.

Kaplinski L, Andreson R, Puurand T and Remm M (2005) MultiPLX: automatic grouping and evaluation of PCR primers. Bioinformatics, 21:1701-1702.

Laan M, Wiebe V, Khusnutdinova E, Remm M, Pääbo S (2005) X-chromosome as a marker for population history: linkage disequilibrium and haplotype study in Eurasian populations. Eur. J Hum Gen 13: 452-462.

Mueller JC, Lõhmussaar E, Mägi R, Remm M, Bettecken T, Lichtner P, Huber S, Illig T, Luedemann J, Schreiber S, Wichmann HE, Pramstaller P, Romeo G, Testa A, Metspalu A and Meitinger T (2005) Comparative analysis of linkage disequilibrium patterns and tagSNP transferability among European populations and HapMap CEPH trios. Am J Hum Genet 76: 387-398.

O'Brien K, Remm M, Sonnhammer E (2005) Inparanoid: The eukaryotic ortholog database. Nucl. Acids Res. 2005 33: D476-D480.

Remm M, Kurg A, Metspalu A (2003)PCR and arrayed primer extension (APEX) for genome-wide linkage disequilibrium (LD) and haplotype mapping. In PCR Technology: Current Innovations ed. HG. Griffin and A. Griffin, CRC Press

Dawson E, Abecasis GR, Bumpstead S, Chen Y, Hunt S, Beare DM, Pabial J, Dibling T, Tinsley E, Kirby S, Carter D, Papaspyridonos M, Livingstone S, Ganske R, Lõhmussaar E, Zernant J, Tõnisson N, Remm M, Mägi R, Puurand T, Vilo J, Kurg A, Rice K, Deloukas P, Mott R, Metspalu A, Bentley DR, Cardon LR, Dunham I (2002)A first generation haplotype map of human chromosome 22. Nature, 418: 544-548

Remm M, Metspalu A (2002)High-density genotyping and linkage disequilibrium in the human genome using chromosome 22 as a model.Current Opinion in Chemical Biology 6: 24-30

Remm M, Storm C, Sonnhammer E (2001)Automatic clustering of orthologs and in-paralogs from pairwise species comparisons. J Mol Biol 314: 1041-1052

Remm M, Sonnhammer E (2000) Classification of transmembrane protein families in the Caenorhabditis elegans genome and identification of human orthologs.Genome Res 10: 1679-1689

Remm M, Remm A, Ustav M (1999) Human papillomavirus type 18 E1 protein is translated from polycistronic mRNA by a discontinuous scanning mechanism.J Virol 73: 3062-3070

Plumpton M, Sharp NA, Liddicoat LH, Remm M, Tucker DO, Hughes FJ, Russell SM, Romanos MA (1995)A high capacity assay for inhibitors of human papillomavirus DNA replication.Biotechnology (NY) 13: 1210-1214

Remm M, Brain R, Jenkins JR (1992)The E2 binding sites determine the efficiency of replication for the origin of human papillomavirus type 18.Nucleic Acids Res 20: 6015-6021

Sturzbecher HW, Brain R, Addison C, Rudge K, Remm M, Grimaldi M, Keenan E, Jenkins JR (1992)A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization.Oncogene 7: 1513-23

last updated: 26.01.2006

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