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Elulookirjeldus (CV)
1.Eesnimi Reet
2.Perekonnanimi Kurg
3.Töökoht Tartu Ülikool, Tehnoloogiainstituut
4.Ametikoht vanemteadur
5.Sünniaeg 15.05.1965 (päev.kuu.aasta)
6.Haridus 1983 - M. Härma nim. Tartu 2. Keskkool
1988 - Tartu Ülikool, füüsika-keemia teaduskond, lõpetanud kiitusega bio-orgaanilise keemia eriala
7.Teenistuskäik 1988-2001 - Eesti Biokeskus, teadur
1998 - stazeerimine USA-s, Baylor College of Medicine, Texas Medical Center, Houston, Texas
2001-2002 - TÜ Tehnoloogiakeskus, erak. vanemtadur
2002-praeguseni - TÜ Tehnoloogiainstituut, vanemteadur
8.Teaduskraad Ph.D (molekulaarbioloogia)
9.Teaduskraadi välja
andnud asutus, aasta		 Tartu ülikool, 2000
10.Tunnustused
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus		 2005 - ASM (American Society of Microbioloy) liige
12.Juhendamisel kaitstud
väitekirjad

Kristiina Sild, MSc, 2004, juh. Reet Kurg. "Veise papilloomiviiruse tüüp 1 E2 valgu tuumasiseste interaktsioonide ja lokalisatsiooni kirjeldamine". Tartu Ülikool

Siim Sõber, MSc, 2004, juh. Reet Kurg. "Papilloomiviiruse L1 valgul põhinevate viiruslaadsete partiklite moodustamine in vitro". Tartu Ülikool
13.Teadustöö põhisuunad molekulaarne viroloogia - papilloomiviiruste stabiilne replikatsioon
molekulaarbioloogia - valkude ekspresseerimine ja puhastamine, nende biokeemiliste omaduste uurimine
14.Jooksvad grandid ETF 5994 (2004-2007) "Pärm kui papilloomiviiruste surrogaatperemees"
15.Teaduspublikatsioonid

Kurg, R., Sild, K., Ilves, A., Sepp, M and M. Ustav (2005) Association of bovine papillomavirus E2 protein with nuclear structures in vivo. J. Virol. 79(16): 10528-10539.

Jarving, R., Jarving, I., Kurg, R., Brash, A.R and N. Samel (2004) On the evolutionary origin of cyclooxygenase (COX) isozymes: characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages. J Biol. Chem. 2004 279(14):13624-13633.

Patent PCT/EE01/000001 "Peptide tag for monitoring and purification of proteins" Inventors: Mart Ustav, Reet Kurg, Niilo Kaldalu

Allikas, A., Örd, D., Kurg, R., Kivi, S. and M. Ustav (2001) Roles of the hinge region and the DNA binding domain of the bovine papillomavirus type 1 E2 protein in initiation of DNA replication. Virus Res. 75: 95-106.

Kivimäe, S., Allikas, A., Kurg, R. and M. Ustav (2001) Replication of a chimeric origin containing elements from Epstein-Barr virus ori P and bovine papillomavirus minimal origin. Virus Res. 75: 1-11.

Koljak, R., Järving, I., Kurg, R., Boeglin, W.E., Varvas, K., Valmsen, K., Ustav, M., Brash, A.B., and N. Samel (2001) The basis of prostaglandin synthesis in coral: Molecular cloning and expression of a cyclooxygenase from the arctic soft coral Gersemia fruticosa. J. Biol. Chem. 276(10): 7033-7040.

Kurg, R. and Ustav, M. (2000) Update to: Monitoring and Purification of Proteins Using Bovine Papillomavirus E2 Tag. In “Cloning and Expression Vectors for Protein Studies”. Ed. by Lu,Q. and M.P. Weiner, Eaton Publ. Natick, MA., Chapter 27.

Kurg, R., Langel, Ü. and M. Ustav (2000) Inhibition of bovine papillomavirus E2 protein activity by peptide nucleic acid. Virus Res. 66: 39-50.

Abou-Zahr, F., Bejjani, B., Kruyt, FA., Kurg, R., Bacino, C., Shapira, SK. and H. Youssoufian (1999) Normal expression of the Fancomi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. Am. J. Med. Genet. 83: 388-391.

Kurg, R., Parik, J., Juronen, E., Sedman, T., Abroi, A., Liiv, I., Langel, Ü. and M. Ustav (1999) Effect of bovine papillomavirus E2 protein specific monoclonal antibodies on papillomavirus DNA replication. J. Virol. 73: 4670-4677.

Abroi, A., Kurg, R. and M. Ustav (1996) Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants. J. Virol. 70: 6169-6179.

viimati muudetud: 12.08.2005

Curriculum Vitae (CV)
1.First Name Reet
2.Surname Kurg
3.Institution Institute of Technology, Unisversity of Tartu
4.Position senior research scientist
5.Date of birth 15.05.1965 (day.month.year)
6.Education 1983 - Tartu Secondary School No. 2
1988 - University of Tartu, Faculty of Physics and Chemistry, graduated cum laude as bio-organic chemist
7.Research and
professional experience		 1988-2001 - Estonian Biocentre, research associate
1998 - working at Baylor College of Medicine, Texas Medical Center, Houston, Texas
2001-2002 - Technology Center of University of Tartu, research scientist
2002-present - Institute of Technology, University of Tartu, senior research scientist
8.Academic degree Ph.D (molecular biology)
9.Dates and sites of
earning the degrees		 University of Tartu, 2000
10.Honours/awards
11.Research-administrative
experience		 2005 - Full Member of American Society of Microbiology
12.Supervised dissertations

Kristiina Sild, MSc, 2004, superv. Reet Kurg. "Veise papilloomiviiruse tüüp 1 E2 valgu tuumasiseste interaktsioonide ja lokalisatsiooni kirjeldamine". Tartu Ülikool

Siim Sõber, MSc, 2004, superv. Reet Kurg. "Papilloomiviiruse L1 valgul põhinevate viiruslaadsete partiklite moodustamine in vitro". Tartu Ülikool
13.Current research program molecular virology - stable replication of papillomaviruses
molecular biology - expression and purification of proteins
14.Current grant funding Grant No. 5994 from Estonian Science Foundation "Investigation of papillomavirus life cycle in yeasts" (2004-2007)
15.List of most important publications

Kurg, R., Sild, K., Ilves, A., Sepp, M and M. Ustav (2005) Association of bovine papillomavirus E2 protein with nuclear structures in vivo. J. Virol. 79(16): 10528-10539.

Jarving, R., Jarving, I., Kurg, R., Brash, A.R and N. Samel (2004) On the evolutionary origin of cyclooxygenase (COX) isozymes: characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages. J Biol. Chem. 2004 279(14):13624-13633.

Patent PCT/EE01/000001 "Peptide tag for monitoring and purification of proteins" Inventors: Mart Ustav, Reet Kurg, Niilo Kaldalu

Allikas, A., Örd, D., Kurg, R., Kivi, S. and M. Ustav (2001) Roles of the hinge region and the DNA binding domain of the bovine papillomavirus type 1 E2 protein in initiation of DNA replication. Virus Res. 75: 95-106.

Kivimäe, S., Allikas, A., Kurg, R. and M. Ustav (2001) Replication of a chimeric origin containing elements from Epstein-Barr virus ori P and bovine papillomavirus minimal origin. Virus Res. 75: 1-11.

Koljak, R., Järving, I., Kurg, R., Boeglin, W.E., Varvas, K., Valmsen, K., Ustav, M., Brash, A.B., and N. Samel (2001) The basis of prostaglandin synthesis in coral: Molecular cloning and expression of a cyclooxygenase from the arctic soft coral Gersemia fruticosa. J. Biol. Chem. 276(10): 7033-7040.

Kurg, R. and Ustav, M. (2000) Update to: Monitoring and Purification of Proteins Using Bovine Papillomavirus E2 Tag. In “Cloning and Expression Vectors for Protein Studies”. Ed. by Lu,Q. and M.P. Weiner, Eaton Publ. Natick, MA., Chapter 27.

Kurg, R., Langel, Ü. and M. Ustav (2000) Inhibition of bovine papillomavirus E2 protein activity by peptide nucleic acid. Virus Res. 66: 39-50.

Abou-Zahr, F., Bejjani, B., Kruyt, FA., Kurg, R., Bacino, C., Shapira, SK. and H. Youssoufian (1999) Normal expression of the Fancomi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. Am. J. Med. Genet. 83: 388-391.

Kurg, R., Parik, J., Juronen, E., Sedman, T., Abroi, A., Liiv, I., Langel, Ü. and M. Ustav (1999) Effect of bovine papillomavirus E2 protein specific monoclonal antibodies on papillomavirus DNA replication. J. Virol. 73: 4670-4677.

Abroi, A., Kurg, R. and M. Ustav (1996) Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants. J. Virol. 70: 6169-6179.

last updated: 12.08.2005

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