[ sulge aken ]
| Elulookirjeldus (CV) | ||
| 1. | Eesnimi | Vladimir |
| 2. | Perekonnanimi | Tšekulajev |
| 3. | Töökoht | Tallinna Tehnikaülikool (TTÜ) |
| 4. | Ametikoht | Keemiainstituudi vanemteadur |
| 5. | Sünniaeg | 23.08.1951 (päev.kuu.aasta) |
| 6. | Haridus | kõrgem, Tallinna Polütehniline Instituut, keemiateaduskond 1969-1974, keemiatehnoloogiainsener |
| 7. | Teenistuskäik | Eesti Teaduste Akadeemia (ETA) Keemia Instituut - vaneminsener 1974-1977 ETA Keemia Instituut - nooremteadur 1977-1984 Moskva Onkoloogia Teaduskeskus - aspirantuur 1984-1987 ETA Keemia Instituut - teadur 1988-1991 TTÜ Keemia Instituut - vanemteadur 1991-käesoleva ajani |
| 8. | Teaduskraad | Bioloogiakandidaat (Ph.D.) |
| 9. | Teaduskraadi välja andnud asutus, aasta |
Moskva Onkoloogia Teaduskeskus, 1988 |
| 10. | Tunnustused | Üleliiduline Leninliku Komsomoli preemia teaduse ja tehnika ala 1981.a. |
| 11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
|
| 12. | Juhendamisel kaitstud väitekirjad |
|
| 13. | Teadustöö põhisuunad | Kasvajarakkude oksüdatiivne stress fotodünaamilisel mõjustusel. |
| 14. | Jooksvad grandid | Tetrapürroolsete ühendite fototoksilise toime uurimine imetajate rakkudel - sihtfinantseerimise grant nr. 0351763s01 (2001-2005), põhitäitja; Mõningate fotoaktiivsete tetrapürroolide ja dendrimeeride kompleksite süntees ja iseloomustamine - ETF grant nr. 5906 (2004-2007), põhitäitja |
| 15. | Teaduspublikatsioonid |
Chekulayeva L.V., Shevchuk I.N., Chekulayev V.A., Ilmarinen K. Hydrogen peroxide, superoxide, and hydroxyl radicals are involved in the phototoxic action of hematoporphyrin derivative against tumor cells. - Journal of Environmental Pathology, Toxicology and Oncology, 2006, v.25(1-2), 51-77. Chekulayeva L., Shevchuk I., Chekulayev V. On the mechanism of the phototoxic action of haematoporphyrin derivative towards tumour cells. - Proc. Estonian Acad. Sci. Biology/Ecology, 2005, v.54(2), 83-119. Chekulayeva L.V., Shevchuk I.N., Chekulayev V.A. Influence of temperature on the efficiency of photodestruction of Ehrlich ascites carcinoma cells sensitized by hematoporphyrin derivative. - Experimental Oncology, 2004, v.26(2), 125-139. Chekulayeva L., Shevchuk I., Chekulayev V. Photodynamic therapy of tumours with chlorin-e6 is pH dependent. - Proc. Estonian Acad. Sci. Biology/Ecology, 2003, v.52(1), 40-54. Chekulayev V., Shevchuk I., Chekulayeva L. On the mechanism of cellular death under photoexcitation of haematoporphyrin derivative. - Proc. Estonian Acad. Sci. Biology/ Ecology, 2003, v.51(1), 55-72. Chekulayev V., Shevchuk I., Chekulayeva L., Jäälaid R. Kinetic studies on the mechanism of hematoporphyrin derivative photobleaching. - Proc. Estonian Acad. Sci. Chemistry, 2002, v.51(1), 49-70. Shevchuk I., Chekulayeva L., Chekulayev V. Influence of pH and glucose administration on the phototoxicity of chlorin-e6 towards Ehrlich carcinoma cells. - Experimental Oncology, 2002, v.24(2), 135-141. Shevchuk I., Chekulayev V., Chekulayeva L. The role of lipid peroxidation and protein degradation in the photodestruction of Ehrlich ascites carcinoma cells sensitized by hematoporphyrin derivative. - Experimental Oncology, 2002, v.24(3), 216-224. Shevchuk I., Chekulayev V., Chekulayeva L. Enhancement of the efficiency of photodynamic therapy of tumours by t-butyl-4-hydroxyanisole. - Journal of Photochemistry and Photobiology B: Biology, 1998, v.45(2-3), 136-143. Chekulayev V., Shevchuk I., Chekulayeva L., Kahru A. Study of the Photochemical and Phototoxic Properties of Lonidamine [1-(2,4-Dichlorobenzyl)-1h-Indazol-3-Carboxylic Acid]. - Journal of Photochemistry and Photobiology B: Biology, 1997, v.41(1-2), 11-21. Shevchuk I., Chekulayev V., Moan J., Berg K. Effects of the inhibitors of energy metabolism, lonidamine and levamisole, on 5-aminolevulinic-acid-induced photochemotherapy. - International Journal of Cancer, 1996, v.67(6), 791-799. |
viimati muudetud: 18.02.2006
| Curriculum Vitae (CV) | ||
| 1. | First Name | Vladimir |
| 2. | Surname | Tšekulajev |
| 3. | Institution | Tallinn University of Technology |
| 4. | Position | Department of Chemistry, senior researcher |
| 5. | Date of birth | 23.08.1951 (day.month.year) |
| 6. | Education | Tallinn Polytechnic Institute, Faculty of Chemistry 1969-1974, graduated as a Dipl. chemical engineer |
| 7. | Research and professional experience |
Institute of Chemistry of the Estonian Academy of Sciences on posititions of senior engineer (1974-1977) and junior researcher (1977-1984) All-Union Oncological Research Centre (Moscow)- postgraduate student 1984-1987 Institute of Chemistry of the Estonian Academy of Sciences - researcher 1988-1991 Department of Chemistry of Tallinn University of Technology - senior researcher (beginning from 1991 to date) |
| 8. | Academic degree | Candidate of Biology (Ph.D.) |
| 9. | Dates and sites of earning the degrees |
All-Union Oncological Research Centre, Moscow, 1988 |
| 10. | Honours/awards | All-Union prize for Leninsky Komsomol for decontamination of wastewater and conservation of natural resources in 1981 |
| 11. | Research-administrative experience |
|
| 12. | Supervised dissertations | |
| 13. | Current research program | Characterization of the adaptive responses of tumour cells to photodynamically-induced oxidative stress. |
| 14. | Current grant funding | Study of the Phototoxic Properties of Tetrapyrroles Towards Mammalian Cells - basic funding grant no. 0351763s01 (2001-2005; Estonian Science Foundation grant no. 5906 (2004-2007) - Synthesis and characterisation of dendrimer complexes of some photoactive tetrapyrrolic compounds |
| 15. | List of most important publications |
Chekulayeva L.V., Shevchuk I.N., Chekulayev V.A., Ilmarinen K. Hydrogen peroxide, superoxide, and hydroxyl radicals are involved in the phototoxic action of hematoporphyrin derivative against tumor cells. - Journal of Environmental Pathology, Toxicology and Oncology, 2006, v.25(1-2), 51-77. Chekulayeva L., Shevchuk I., Chekulayev V. On the mechanism of the phototoxic action of haematoporphyrin derivative towards tumour cells. - Proc. Estonian Acad. Sci. Biology/Ecology, 2005, v.54(2), 83-119. Chekulayeva L.V., Shevchuk I.N., Chekulayev V.A. Influence of temperature on the efficiency of photodestruction of Ehrlich ascites carcinoma cells sensitized by hematoporphyrin derivative. - Experimental Oncology, 2004, v.26(2), 125-139. Chekulayeva L., Shevchuk I., Chekulayev V. Photodynamic therapy of tumours with chlorin-e6 is pH dependent. - Proc. Estonian Acad. Sci. Biology/Ecology, 2003, v.52(1), 40-54. Chekulayev V., Shevchuk I., Chekulayeva L. On the mechanism of cellular death under photoexcitation of haematoporphyrin derivative. - Proc. Estonian Acad. Sci. Biology/ Ecology, 2003, v.51(1), 55-72. Chekulayev V., Shevchuk I., Chekulayeva L., Jäälaid R. Kinetic studies on the mechanism of hematoporphyrin derivative photobleaching. - Proc. Estonian Acad. Sci. Chemistry, 2002, v.51(1), 49-70. Shevchuk I., Chekulayeva L., Chekulayev V. Influence of pH and glucose administration on the phototoxicity of chlorin-e6 towards Ehrlich carcinoma cells. - Experimental Oncology, 2002, v.24(2), 135-141. Shevchuk I., Chekulayev V., Chekulayeva L. The role of lipid peroxidation and protein degradation in the photodestruction of Ehrlich ascites carcinoma cells sensitized by hematoporphyrin derivative. - Experimental Oncology, 2002, v.24(3), 216-224. Shevchuk I., Chekulayev V., Chekulayeva L. Enhancement of the efficiency of photodynamic therapy of tumours by t-butyl-4-hydroxyanisole. - Journal of Photochemistry and Photobiology B: Biology, 1998, v.45(2-3), 136-143. Chekulayev V., Shevchuk I., Chekulayeva L., Kahru A. Study of the Photochemical and Phototoxic Properties of Lonidamine [1-(2,4-Dichlorobenzyl)-1h-Indazol-3-Carboxylic Acid]. - Journal of Photochemistry and Photobiology B: Biology, 1997, v.41(1-2), 11-21. Shevchuk I., Chekulayev V., Moan J., Berg K. Effects of the inhibitors of energy metabolism, lonidamine and levamisole, on 5-aminolevulinic-acid-induced photochemotherapy. - International Journal of Cancer, 1996, v.67(6), 791-799. |
last updated: 18.02.2006
[ sulge aken ]