[ sulge aken ]
| Elulookirjeldus (CV) | ||
| 1. | Eesnimi | Toomas |
| 2. | Perekonnanimi | Tiivel |
| 3. | Töökoht | Stockholmi Spordikõrgkool |
| 4. | Ametikoht | külalisteadur |
| 5. | Sünniaeg | 10.08.1971 (päev.kuu.aasta) |
| 6. | Haridus | kõrgem, TTÜ, 1994, orgaaniliste ainete tehnoloogia insener |
| 7. | Teenistuskäik | 1988-1994 Keemilise ja Bioloogilise Füüsika Instituut, tehnik 1994-1996 Keemilise ja Bioloogilise Füüsika Instituut, insener 1996-2002 Keemilise ja Bioloogilise Füüsika Instituut, teadur 2002-2003 Keemilise ja Bioloogilise Füüsika Instituut, vanemteadur 2003-2005 Tartu Ülikool, järeldoktor, erakorraline teadur 2005- Stockholmi Spordikõrgkool, külalisteadur |
| 8. | Teaduskraad | PhD |
| 9. | Teaduskraadi välja andnud asutus, aasta |
Joseph Fourier Ülikool, Grenoble 1, Prantsusmaa ja Tallinna Tehnikaülikool, 2002 |
| 10. | Tunnustused | |
| 11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
|
| 12. | Juhendamisel kaitstud väitekirjad |
|
| 13. | Teadustöö põhisuunad | Lihasraku bioenergeetika ja biokeemia |
| 14. | Jooksvad grandid | ETF 6142 Kompartmentaliseeritud energia transpordi võrgud kardiomüotsüütides ja eelkohastumise mehhanismid ETF 5515 Mitokondrite ja ATPaaside funktsionaalsed kompleksid kui energeetilise metabolismi põhiüksused oksüdatiivsetes lihasrakkudes |
| 15. | Teaduspublikatsioonid |
Anmann T, Eimre M, Kuznetsov AV, Andrienko T, Kaambre T, Sikk P, Seppet E, Tiivel T, Vendelin M, Seppet E, Saks VA. Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells. FEBS J. 2005 Jun;272(12):3145-61. Andrienko T, Kuznetsov AV, Kaambre T, Usson Y, Orosco A, Appaix F, Tiivel T, Sikk P, Vendelin M, Margreiter R, Saks VA. Metabolic consequences of functional complexes of mitochondria, myofibrils and sarcoplasmic reticulum in muscle cells. J Exp Biol. 2003 Jun;206(Pt 12):2059-72. Review. Walsh B, Tiivel T, Tonkonogi M, Sahlin K. Increased concentrations of P(i) and lactic acid reduce creatine-stimulated respiration in muscle fibers. J Appl Physiol. 2002 Jun;92(6):2273-6. Seppet EK, Kaambre T, Sikk P, Tiivel T, Vija H, Tonkonogi M, Sahlin K, Kay L, Appaix F, Braun U, Eimre M, Saks VA. Functional complexes of mitochondria with Ca,MgATPases of myofibrils and sarcoplasmic reticulum in muscle cells. Biochim Biophys Acta. 2001 Apr 2;1504(2-3):379-95. Saks, VA; Tiivel, T; Sikk, P; Kaambre, T; Kay, L; Tonkonogi, M; Seppet, E; Sahlin, K Metabolic channelling in cardiac cells: Dependence of kinetics of respiration regulation on source of ADP. Biophysical Journal 2000 Jan 2; 78 (1): 1161 Tiivel T, Kadaya L, Kuznetsov A, Kaambre T, Peet N, Sikk P, Braun U, Ventura-Clapier R, Saks V, Seppet EK. Developmental changes in regulation of mitochondrial respiration by ADP and creatine in rat heart in vivo. Mol Cell Biochem. 2000 May;208(1-2):119-28. Tonkonogi M, Walsh B, Tiivel T, Saks V, Sahlin K. Mitochondrial function in human skeletal muscle is not impaired by high intensity exercise. Pflugers Arch. 1999 Mar;437(4):562-8. Saks VA, Veksler VI, Kuznetsov AV, Kay L, Sikk P, Tiivel T, Tranqui L, Olivares J, Winkler K, Wiedemann F, Kunz WS. Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo. Mol Cell Biochem. 1998 Jul;184(1-2):81-100. Kay L, Li Z, Mericskay M, Olivares J, Tranqui L, Fontaine E, Tiivel T, Sikk P, Kaambre T, Samuel JL, Rappaport L, Usson Y, Leverve X, Paulin D, Saks VA. Study of regulation of mitochondrial respiration in vivo. An analysis of influence of ADP diffusion and possible role of cytoskeleton. Biochim Biophys Acta. 1997 Nov 10;1322(1):41-59. Kuznetsov AV, Tiivel T, Sikk P, Kaambre T, Kay L, Daneshrad Z, Rossi A, Kadaja L, Peet N, Seppet E, Saks VA. Striking differences between the kinetics of regulation of respiration by ADP in slow-twitch and fast-twitch muscles in vivo. Eur J Biochem. 1996 Nov 1;241(3):909-15. Saks VA, Tiivel T, Kay L, Novel-Chate V, Daneshrad Z, Rossi A, Fontaine E, Keriel C, Leverve X, Ventura-Clapier R, Anflous K, Samuel JL, Rappaport L. On the regulation of cellular energetics in health and disease. Mol Cell Biochem. 1996 Jul-Aug;160-161:195-208. Review. Saks VA, Kuznetsov AV, Khuchua ZA, Vasilyeva EV, Belikova JO, Kesvatera T, Tiivel T. Control of cellular respiration in vivo by mitochondrial outer membrane and by creatine kinase. A new speculative hypothesis: possible involvement of mitochondrial-cytoskeleton interactions. J Mol Cell Cardiol. 1995 Jan;27(1):625-45. Tougu V, Tiivel T, Talts P, Siksnis V, Poyarkova S, Kesvatera T, Aaviksaar A. Electrostatic effects in trypsin reactions. Influence of salts. Eur J Biochem. 1994 Jun 1;222(2):475-81. |
viimati muudetud: 13.01.2007
| Curriculum Vitae (CV) | ||
| 1. | First Name | Toomas |
| 2. | Surname | Tiivel |
| 3. | Institution | The Swedish School of Sport and Health Sciences |
| 4. | Position | visiting scientist |
| 5. | Date of birth | 10.08.1971 (day.month.year) |
| 6. | Education | higher, Tallinn Technical University, 1994, engineer of technology of organic compounds |
| 7. | Research and professional experience |
1988-1994 National Institute of Chemical Physics and Biophysics, techncian 1994-1996 National Institute of Chemical Physics and Biophysics, engineer 1996-2002 National Institute of Chemical Physics and Biophysics, research scientist 2002-2003 National Institute of Chemical Physics and Biophysics, senior research scientist 2003-2005 University of Tartu, post-doctoral studies, research scientist 2005- The Swedish School of Sport and Health Sciences, visiting scientist |
| 8. | Academic degree | PhD |
| 9. | Dates and sites of earning the degrees |
University Joseph Fourier, Grenoble 1, France and Tallinn Technical University, 2002 |
| 10. | Honours/awards | |
| 11. | Research-administrative experience |
|
| 12. | Supervised dissertations | |
| 13. | Current research program | Bioenergetics and biochemistry of muscle cell |
| 14. | Current grant funding | ESF grant 6142, Compartmentalized energy transfer in cardiomyocytes and mechanisms of preconditioning ESF grant 5515, Functional complexes of mitochondria with ATPases as the principal units of energetic metabolism in oxidative muscle cells |
| 15. | List of most important publications |
Anmann T, Eimre M, Kuznetsov AV, Andrienko T, Kaambre T, Sikk P, Seppet E, Tiivel T, Vendelin M, Seppet E, Saks VA. Calcium-induced contraction of sarcomeres changes the regulation of mitochondrial respiration in permeabilized cardiac cells. FEBS J. 2005 Jun;272(12):3145-61. Andrienko T, Kuznetsov AV, Kaambre T, Usson Y, Orosco A, Appaix F, Tiivel T, Sikk P, Vendelin M, Margreiter R, Saks VA. Metabolic consequences of functional complexes of mitochondria, myofibrils and sarcoplasmic reticulum in muscle cells. J Exp Biol. 2003 Jun;206(Pt 12):2059-72. Review. Walsh B, Tiivel T, Tonkonogi M, Sahlin K. Increased concentrations of P(i) and lactic acid reduce creatine-stimulated respiration in muscle fibers. J Appl Physiol. 2002 Jun;92(6):2273-6. Seppet EK, Kaambre T, Sikk P, Tiivel T, Vija H, Tonkonogi M, Sahlin K, Kay L, Appaix F, Braun U, Eimre M, Saks VA. Functional complexes of mitochondria with Ca,MgATPases of myofibrils and sarcoplasmic reticulum in muscle cells. Biochim Biophys Acta. 2001 Apr 2;1504(2-3):379-95. Saks, VA; Tiivel, T; Sikk, P; Kaambre, T; Kay, L; Tonkonogi, M; Seppet, E; Sahlin, K Metabolic channelling in cardiac cells: Dependence of kinetics of respiration regulation on source of ADP. Biophysical Journal 2000 Jan 2; 78 (1): 1161 Tiivel T, Kadaya L, Kuznetsov A, Kaambre T, Peet N, Sikk P, Braun U, Ventura-Clapier R, Saks V, Seppet EK. Developmental changes in regulation of mitochondrial respiration by ADP and creatine in rat heart in vivo. Mol Cell Biochem. 2000 May;208(1-2):119-28. Tonkonogi M, Walsh B, Tiivel T, Saks V, Sahlin K. Mitochondrial function in human skeletal muscle is not impaired by high intensity exercise. Pflugers Arch. 1999 Mar;437(4):562-8. Saks VA, Veksler VI, Kuznetsov AV, Kay L, Sikk P, Tiivel T, Tranqui L, Olivares J, Winkler K, Wiedemann F, Kunz WS. Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo. Mol Cell Biochem. 1998 Jul;184(1-2):81-100. Kay L, Li Z, Mericskay M, Olivares J, Tranqui L, Fontaine E, Tiivel T, Sikk P, Kaambre T, Samuel JL, Rappaport L, Usson Y, Leverve X, Paulin D, Saks VA. Study of regulation of mitochondrial respiration in vivo. An analysis of influence of ADP diffusion and possible role of cytoskeleton. Biochim Biophys Acta. 1997 Nov 10;1322(1):41-59. Kuznetsov AV, Tiivel T, Sikk P, Kaambre T, Kay L, Daneshrad Z, Rossi A, Kadaja L, Peet N, Seppet E, Saks VA. Striking differences between the kinetics of regulation of respiration by ADP in slow-twitch and fast-twitch muscles in vivo. Eur J Biochem. 1996 Nov 1;241(3):909-15. Saks VA, Tiivel T, Kay L, Novel-Chate V, Daneshrad Z, Rossi A, Fontaine E, Keriel C, Leverve X, Ventura-Clapier R, Anflous K, Samuel JL, Rappaport L. On the regulation of cellular energetics in health and disease. Mol Cell Biochem. 1996 Jul-Aug;160-161:195-208. Review. Saks VA, Kuznetsov AV, Khuchua ZA, Vasilyeva EV, Belikova JO, Kesvatera T, Tiivel T. Control of cellular respiration in vivo by mitochondrial outer membrane and by creatine kinase. A new speculative hypothesis: possible involvement of mitochondrial-cytoskeleton interactions. J Mol Cell Cardiol. 1995 Jan;27(1):625-45. Tougu V, Tiivel T, Talts P, Siksnis V, Poyarkova S, Kesvatera T, Aaviksaar A. Electrostatic effects in trypsin reactions. Influence of salts. Eur J Biochem. 1994 Jun 1;222(2):475-81. |
last updated: 13.01.2007
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