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Elulookirjeldus (CV)
1.Eesnimi Illar
2.Perekonnanimi Pata
3.Töökoht Tallinna Tehnikaülikool, geenitehnoloogia instituut
4.Ametikoht vanemteadur
5.Sünniaeg 04.07.1967 (päev.kuu.aasta)
6.Haridus Tartu Ülikool, bioloogia 1991
7.Teenistuskäik 1991-97, 98-99: teadur, Tartu Ülikooli molekulaar- ja rakubioloogia instituut;
2000-03: vanemteadur, Tartu Ülikooli zooloogia ja hüdrobioloogia instituut;
2004-05: teadur, Keemilise ja Bioloogilise Füüsika Instituut.
Järeldoktoriõpe:
1997: EMBO stipendium F. Grosveldi laboris (Rotterdami Erasmuse Ülikool);
1997-99: külalisteadur H. Sariola laboris (Helsingi Ülikool);
2003-04: teadur R. Allikmetsa laboris (Columbia Ülikool, New York).
8.Teaduskraad PhD
9.Teaduskraadi välja
andnud asutus, aasta		 Tartu Ülikool, 1996
10.Tunnustused
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
12.Juhendamisel kaitstud
väitekirjad

Kaia Kala, MSc, 2005, juh. Illar Pata, Jüri Kärner. Generation and characterisation of conditional transgenic mouse lines expressing Cre under the regulation of the mouse Hoxb7 promoter fragment. Tartu Ülikool

Merlin Ploom, MSc, 2005, juh. Illar Pata, Madis Jakobson, Raivo Raid. shRNA-l põhineva geenivaigistusmeetodi rakendamine neeru morfogeneesi uurimisel. Tartu Ülikool
13.Teadustöö põhisuunad Imetajate kusesuguelundkonna areng; konditsionaalne ja indutseeritud mutagenees hiires; lentiviirusvektorite arendamine.
14.Jooksvad grandid Hedgehogi signaaliraja aktiivsuse moduleerimine in vivo: selle võimalused kasvajate ravis (ETF nr 6139).
15.Teaduspublikatsioonid

Karis, A., Pata, I., Van Doorninck, J. H., Grosveld, F., De Zeeuw, C. I., De Caprona, D., & Fritzsch, B. (2001). Transcription Factor Gata-3 Alters Pathway Selection of Olivocochlear Neurons and Affects Morphogenesis of the Ear. Journal of Comparative Neurology, 429(4), 615-630.

Krinka, D., Raid, R., Pata, I., Kärner, J., & Maimets, T. (2001). In Situ Hybridisation of Chick Embryos With P53-Specific Probe and Their Immunostaining With Anti-P53 Antibodies. Anatomy and Embryology, 204(3), 207-215.

Meng, X. J., Pata, I., Pedrono, E., Popsueva, A., De Rooij, D. G., Janne, M., Rauvala, H., & Sariola, H. (2001). Transient Disruption of Spermatogenesis by Deregulated Expression of Neurturin in Testis. Molecular and Cellular Endocrinology, 184(1-2), 33-39.

Pata, I., Studer, M., Van Doorninck, J. H., Briscoe, J., Kuuse, S., Engel, J. D., Grosveld, F., & Karis, A. (1999). The Transcription Factor Gata3 Is a Downstream Effector of Hoxb1 Specification in Rhombomere 4. Development, 126(23), 5523-5531.

Tensing, K., Pata, I., Wittig, I., Wehnert, M., & Metspalu, A. (1999). Genomic Organization of the Human Complex I 13-Kda Subunit Gene Ndufa5. Cytogenetics and Cell Genetics, 84(1-2), 125-127.

Annilo, T., Jelina, J., Pata, I., & Metspalu, A. (1998). Isolation and Characterization of the Mouse Ribosomal Protein S7 Gene. Biochemistry and Molecular Biology International, 46(2), 287-295.

Pata, I. and Truve, E. (1998) Gel electrophoresis, transfer and hybridisation of nucleic acids. In Basic Cloning Procedures (ed. V. Berzins), pp. 104-134. Heidelberg: Springer.

Rebane, A., Tamme, R., Laan, M., Pata, I., & Metspalu, A. (1998). A Novel Snorna (U73) Is Encoded Within the Introns of the Human and Mouse Ribosomal Protein S3a Genes. Gene, 210(2), 255-263.

Pata, I., Tensing, K., & Metspalu, A. (1997). A Human Cdna Encoding the Homologue of Nadh:Ubiquinone Oxidoreductase Subunit B13. Biochimica Et Biophysica Acta-Gene Structure and Expression, 1350(2), 115-118.

Pata, I. and Metspalu, A. (1996) Structural characterization of the mouse ribosomal protein S6-encoding gene. Gene 175, 241-245.

Pata, I., and Metspalu, A. (1993) A dinucleotide repeat polymorphism at the ribosomal protein S6 gene. Hum Mol Genet 2: 1749.

Pata, I., Hoth, S., Kruppa, J., and Metspalu, A. (1992) The human ribosomal protein S6 gene: isolation, primary structure and location in chromosome 9. Gene 121: 387-392.

viimati muudetud: 27.09.2005

Curriculum Vitae (CV)
1.First Name Illar
2.Surname Pata
3.Institution Tallinn University of Technology, Dept Gene Technology
4.Position senior research scientist
5.Date of birth 04.07.1967 (day.month.year)
6.Education University of Tartu, biology, 1991
7.Research and
professional experience		 1991-97, 98-99: research scientist, Institute of Molecular and Cell Biology, University of Tartu;
2000-03: senior research scientist, Institute of Zoology and Hydrobiology, University of Tartu;
2004-05: scientist, National Institute of Chemical Physics and Biophysics.
Postdoctoral training:
1997: EMBO fellowship at Frank Grosveld's lab (Erasmus University Rotterdam, Netherlands);
1998-99: Estonian Science Foundation postdoctoral fellowship;
1997-99: visiting research fellow at Hannu Sariola’s lab (University of Helsinki, Finland);
2003-04: postdoctoral research scientist at Rando Allikmets’ lab (Columbia University, New York).
8.Academic degree PhD
9.Dates and sites of
earning the degrees		 University of Tartu, 1996
10.Honours/awards
11.Research-administrative
experience
12.Supervised dissertations

Kaia Kala, MSc, 2005, superv. Illar Pata, Jüri Kärner. Generation and characterisation of conditional transgenic mouse lines expressing Cre under the regulation of the mouse Hoxb7 promoter fragment. Tartu Ülikool

Merlin Ploom, MSc, 2005, superv. Illar Pata, Madis Jakobson, Raivo Raid. shRNA-l põhineva geenivaigistusmeetodi rakendamine neeru morfogeneesi uurimisel. Tartu Ülikool
13.Current research program Development of mammalian urogenital system; conditional and inducible mutagenesis in mice; lentiviral vectors in mammalian models.
14.Current grant funding Modulation of the Hedgehog Signalling Activity In Vivo:
Its Potential In Cancer Therapy (ESF No 6139).
15.List of most important publications

Karis, A., Pata, I., Van Doorninck, J. H., Grosveld, F., De Zeeuw, C. I., De Caprona, D., & Fritzsch, B. (2001). Transcription Factor Gata-3 Alters Pathway Selection of Olivocochlear Neurons and Affects Morphogenesis of the Ear. Journal of Comparative Neurology, 429(4), 615-630.

Krinka, D., Raid, R., Pata, I., Kärner, J., & Maimets, T. (2001). In Situ Hybridisation of Chick Embryos With P53-Specific Probe and Their Immunostaining With Anti-P53 Antibodies. Anatomy and Embryology, 204(3), 207-215.

Meng, X. J., Pata, I., Pedrono, E., Popsueva, A., De Rooij, D. G., Janne, M., Rauvala, H., & Sariola, H. (2001). Transient Disruption of Spermatogenesis by Deregulated Expression of Neurturin in Testis. Molecular and Cellular Endocrinology, 184(1-2), 33-39.

Pata, I., Studer, M., Van Doorninck, J. H., Briscoe, J., Kuuse, S., Engel, J. D., Grosveld, F., & Karis, A. (1999). The Transcription Factor Gata3 Is a Downstream Effector of Hoxb1 Specification in Rhombomere 4. Development, 126(23), 5523-5531.

Tensing, K., Pata, I., Wittig, I., Wehnert, M., & Metspalu, A. (1999). Genomic Organization of the Human Complex I 13-Kda Subunit Gene Ndufa5. Cytogenetics and Cell Genetics, 84(1-2), 125-127.

Annilo, T., Jelina, J., Pata, I., & Metspalu, A. (1998). Isolation and Characterization of the Mouse Ribosomal Protein S7 Gene. Biochemistry and Molecular Biology International, 46(2), 287-295.

Pata, I. and Truve, E. (1998) Gel electrophoresis, transfer and hybridisation of nucleic acids. In Basic Cloning Procedures (ed. V. Berzins), pp. 104-134. Heidelberg: Springer.

Rebane, A., Tamme, R., Laan, M., Pata, I., & Metspalu, A. (1998). A Novel Snorna (U73) Is Encoded Within the Introns of the Human and Mouse Ribosomal Protein S3a Genes. Gene, 210(2), 255-263.

Pata, I., Tensing, K., & Metspalu, A. (1997). A Human Cdna Encoding the Homologue of Nadh:Ubiquinone Oxidoreductase Subunit B13. Biochimica Et Biophysica Acta-Gene Structure and Expression, 1350(2), 115-118.

Pata, I. and Metspalu, A. (1996) Structural characterization of the mouse ribosomal protein S6-encoding gene. Gene 175, 241-245.

Pata, I., and Metspalu, A. (1993) A dinucleotide repeat polymorphism at the ribosomal protein S6 gene. Hum Mol Genet 2: 1749.

Pata, I., Hoth, S., Kruppa, J., and Metspalu, A. (1992) The human ribosomal protein S6 gene: isolation, primary structure and location in chromosome 9. Gene 121: 387-392.

last updated: 27.09.2005

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