ERIS - Eesti teadus- ja arendustegevuse infosüsteem

Elulookirjeldus (CV)
1.	Eesnimi	Karin
2.	Perekonnanimi	Valmsen
3.	Töökoht	TTÜ Matemaatika-loodusteaduskond Bioorgaanilise keemia õppetool
4.	Ametikoht	teadur
5.	Sünniaeg	02.10.1960 (päev.kuu.aasta)
6.	Haridus	loodusteaduste magister
7.	Teenistuskäik	1986-1990 nooremteadur Eesti TA Keemilise ja Bioloogilise Füüsika Instituut. 1990-1996 nooremteadur Eesti TA Keemia Instituudis. 1996-1997 külalisteadur, Department of Pharmacology, Uppsala University, Sweden.1997- tänaseni teadur TTÜ keemiainstituudis
8.	Teaduskraad	loodusteaduste magister
9.	Teaduskraadi välja andnud asutus, aasta	1999
10.	Tunnustused	Eesti Vabariigi Teaduspreemia keemia ja molekulaarbioloogia alal, “Prostaglandiinide biosüntees korallides" eest 2002.a. (teaduskollektiivi liige)
11.	Teadusorganisatsiooniline ja –administratiivne tegevus	Eesti Keemia seltsi liige, Eesti Biokeemia Seltsi liige
12.	Juhendamisel kaitstud väitekirjad
13.	Teadustöö põhisuunad	Prostaglandiinide süntees korallis Plexaura homomalla. Prostaglandiinide sünteesi 15. asendi oksüdatsiooni stereospetsiifika aminohappelised determinandid.
14.	Jooksvad grandid	Osalen põhitäitjana ETF Grant nr 5639 (2003-2006, grandihoidja N.Samel) ja NIH grant 2001-2005 (Eesti poolne garndihoidja N.Samel) täitmisel.
15.	Teaduspublikatsioonid	Valmsen K., Boeglin W.E., Järving I., Schneider C., Varvas K., Brash A.R., Samel N. Structural and Functional Comparison of 15S- and 15R-specific Cyclooxygenases from the Coral Plexaura homomalla. Eur. J. Biochem., 2004, 271, 3533-3538. Koljak R., Järving I., Kurg R., Boeglin W.E., Varvas K., Valmsen K., Ustav M., Brash, A.R., Samel N. The Basis of Prostaglandin synthesis in Coral: Molecular Cloning and Expression of a Cyclooxygenase from the Arctic Soft Coral Gersemia fruticosa. J. Biol. Chem., 2001, 276, 7033-7040. Valmsen K., Järving I., Boeglin W.E., Varvas K., Koljak R., Brash A.R., Samel N. 15R-Cyclooxygenase of Invertebrate Origin: Molecular Cloning and Expression from the Caribbean Coral Plexaura homomalla. Proc. Natl. Acad. Sci. U.S.A., 2001, 98, 7700-7705. Varvas K, Jarving I, Koljak R, Valmsen K, Brash AR, Samel N. Evidence of a cyclooxygenase-related prostaglandin synthesis in coral. The allene oxide pathway is not involved in prostaglandin biosynthesis. J Biol Chem. 1999 Apr 9;274(15):9923-9. Bylund J, Kunz T, Valmsen K, Oliw EH. Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes. J Pharmacol Exp Ther. 1998 Jan;284(1):51-60.

viimati muudetud: 28.09.2005

Curriculum Vitae (CV)
1.	First Name	Karin
2.	Surname	Valmsen
3.	Institution	Tallinn Technical University (TTU), Faculty of Science, Dept. of Chemistry, Chair of Bioorganic Chemistry
4.	Position	research scientist
5.	Date of birth	02.10.1960 (day.month.year)
6.	Education	MSc of sciences
7.	Research and professional experience	1986-1990 Junior Research Scientist, Institute of Chemical Physics and Biophysics, Estonian Academy of Sciences.1990-1996 Junior Research Scientist, Institute of Chemistry, Estonian Academy of Sciences.1996-1997 Research Fellow, Department of Pharmacology, Uppsala University, Sweden.1997- at present Research Scientist, Institute of Chemistry,TTU.
8.	Academic degree	Msc of sciences
9.	Dates and sites of earning the degrees	1999
10.	Honours/awards	National Prize for Chemistry and Molecular Biology in 2002, "Biosynthesis of Prostaglandins in Invertebrates"
11.	Research-administrative experience	Member of Estonian Chemical Society, Member of Estonian Biochemical Society
12.	Supervised dissertations
13.	Current research program	Prostaglandin synthesis in soft coral Plexaura homomalla. Amino acids determinants of oxygenation stereospecificity at C-15.
14.	Current grant funding	Investigator, ESF grant No. 5639 (2003-2006, P.I.- N.Samel); Suppl. (N.Samel) of NIH (USA) grant GM-53638 (P.I. A.R.Brash) "Novel Oxygenations of Fatty Acids" (2001-2005).
15.	List of most important publications	Valmsen K., Boeglin W.E., Järving I., Schneider C., Varvas K., Brash A.R., Samel N. Structural and Functional Comparison of 15S- and 15R-specific Cyclooxygenases from the Coral Plexaura homomalla. Eur. J. Biochem., 2004, 271, 3533-3538. Koljak R., Järving I., Kurg R., Boeglin W.E., Varvas K., Valmsen K., Ustav M., Brash, A.R., Samel N. The Basis of Prostaglandin synthesis in Coral: Molecular Cloning and Expression of a Cyclooxygenase from the Arctic Soft Coral Gersemia fruticosa. J. Biol. Chem., 2001, 276, 7033-7040. Valmsen K., Järving I., Boeglin W.E., Varvas K., Koljak R., Brash A.R., Samel N. 15R-Cyclooxygenase of Invertebrate Origin: Molecular Cloning and Expression from the Caribbean Coral Plexaura homomalla. Proc. Natl. Acad. Sci. U.S.A., 2001, 98, 7700-7705. Varvas K, Jarving I, Koljak R, Valmsen K, Brash AR, Samel N. Evidence of a cyclooxygenase-related prostaglandin synthesis in coral. The allene oxide pathway is not involved in prostaglandin biosynthesis. J Biol Chem. 1999 Apr 9;274(15):9923-9. Bylund J, Kunz T, Valmsen K, Oliw EH. Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes. J Pharmacol Exp Ther. 1998 Jan;284(1):51-60.

last updated: 28.09.2005