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Elulookirjeldus (CV)
1.Eesnimi Liina
2.Perekonnanimi Kangur
3.Töökoht TÜ Füüsika Instituut
4.Ametikoht erakorraline teadur
5.Sünniaeg 01.03.1971 (päev.kuu.aasta)
6.Haridus Aastatel 1989 - 1997 õppisin Tartu Ülikooli füüsika-keemia teaduskonnas keemia erialal,
Aastatel 1997 – 2000 õppisin Tartu Ülikooli bioloogia-geoloogia teaduskonnas biokeemia erialal,
30.06.1997 - 30.11.1997 õppisin Kieli Christian-Albrecti Ülikoolis TEMPUS JEP projekti No 09270-95 raames.
2000. a. astusin doktoriõppesse Tallinna Tehnikaülikooli bio- ja toiduainete tehnoloogia erialale.
7.Teenistuskäik 1. jan 2002 kuni 30. apr 2003 TÜ teadur
1. mai 2003 kuni 31. dets. 2003 TTÜ erak. teadur
1. jan 2004 kuni 31. sept. 2005 TTÜ teadur
1. okt 2005 - TÜ FI erak. teadur
8.Teaduskraad M.Sc. biokeemias
9.Teaduskraadi välja
andnud asutus, aasta
Tartu Ülikool, 2000
10.Tunnustused
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
Alates nov. 2003 Eesti Loodusuurijate Seltsi (Assotsieerunud Eesti Teaduste Akadeemiaga 23.01.1998) tegevliige
12.Juhendamisel kaitstud
väitekirjad
13.Teadustöö põhisuunad 1. Madalmolekulaarsete metalle sisaldavate valkude ekspresseerimine, isoleerimine ja iseloomustamine.
2. Bioloogiliste molekulide spektroskoopiline iseloomustamine UV-, VIS- ja luminestsents-.
3. Piimhappe produktsiooni optimeerimine ja tööstuslik tootmine.
14.Jooksvad grandid "Tsingi metabolismi roll Alzheimeri haiguses. Uue strateegia väljatöötamine Alzheimeri haiguse preventsiooniks ja raviks" Granti hoida P. Palumaa 2003-2006
15.Teaduspublikatsioonid

Palumaa P, Tammiste I, Kruusel K, Kangur L, Jornvall H, Sillard R. Metal binding of metallothionein-3 versus metallothionein-2: lower affinity and higher plasticity. Biochim Biophys Acta. 2005 Mar 14;1747(2):205-11. Epub 2004 Dec 19. PMID: 15698955 [PubMed - indexed for MEDLINE]

Palumaa P., Voronova A., Kangur L., Sillard R., Meyer-Klaucke W., Meyer T., Rompel A.Mammalian copper chaperone Cox17 exists in two metalloforms, linked by oxidative switch Abstract number: G2-098P, 30th FEBS Congress - 9th IUBMB Conference, The Protein World Proteins and Peptides: Structure, Function and Organization, Budapest, Hungary 2nd-7th July, 2005

Palumaa P, Kangur L, Voronova A, Sillard R. Metal-binding mechanism of Cox17, a copper chaperone for cytochrome c oxidase. Biochem J. 2004 Aug 15;382(Pt 1):307-14. PMID: 15142040 [PubMed - indexed for MEDLINE]

Palumaa P, Eriste E, Kruusel K, Kangur L, Jornvall H, Sillard R. Metal binding to brain-specific metallothionein-3 studied by electrospray ionization mass spectrometry. Cell Mol Biol (Noisy-le-grand). 2003 Jul;49(5):763-8. PMID: 14528913 [PubMed - indexed for MEDLINE]

Nurk A, Simisker J, Kangur L, Medijainen L, Heinaru E, Heinaru A. A novel thermophilic isolate for the production of L(+)-lactate. The 9th International Symposium on the Genetics of Industrial Microorganisms Abstract book. Gyeongju, Korea 1.– 5.06 2002

Kangur L, Palumaa P. The effects of physiologically important nonmetallic ligands in the reactivity of metallothionein towards 5,5'-dithiobis(2-nitrobenzoic acid). A new method for the determination of ligand interactions with metallothionein. Eur J Biochem. 2001 Sep;268(18):4979-84. PMID: 11559367 [PubMed - indexed for MEDLINE]

Bonetto V, Kangur L, Palumaa P, Mutt V, Jornvall H, Sillard R. Large-scale HPLC purification of calbindin D9k from porcine intestine. Protein Expr Purif. 1999 Dec;17(3):387-91. PMID: 10600456 [PubMed - indexed for MEDLINE]

viimati muudetud: 06.10.2005

Curriculum Vitae (CV)
1.First Name Liina
2.Surname Kangur
3.Institution Institute of Physics, University of Tartu
4.Position scientist
5.Date of birth 01.03.1971 (day.month.year)
6.Education 1989 - 1997 bachelor student University of Tartu in Faculty on Physics and Chemistry in chemical sciences.
1997 - 2000 master student University of Tartu in Faculty of Biology and Geography by Institute of Molecular and Cell Biology in biochemical sciences.
30.06. - 30.11. 1997 I studied in Christian-Albrechts-University of Kiel within the framework of a TEMPUS JEP project No 09270-95.
Since 2000 doctoral student Tallinn University of Technology
in study programm Chemical and Materials Technology.
7.Research and
professional experience
From 1. jan 2002 to 30. apr 2003 UT scientist
From 1. may 2003 to 31. dec 2003 TUT scientist
From 1. jan 2004 to 3o. sep 2005 TUT scientist
Since 1. oct 2005 scientist in Institute of Physics, University of Tartu
8.Academic degree M.Sc. in biochemistry
9.Dates and sites of
earning the degrees
University of Tartu , 2000
10.Honours/awards
11.Research-administrative
experience
Since nov 2003 active member of Estonian Naturalists’ Society (Associated with the Estonian Academy of Sciences 23.01.1998)
12.Supervised dissertations
13.Current research program 1. Expression, isolation and characterization of low-molecular weight metal containing proteins.
2. UV, VIS and luminescense spectroscopic characterization of biological molecules.
3. Optimization of microbiological lactic acid production for industrial production.
14.Current grant funding Zinc metabolism in Alzheimer's disease. Development of the new strategy to prevention and therapy of Alzheimers Disease. Grant keeper P. Palumaa 2003 - 2006
15.List of most important publications

Palumaa P, Tammiste I, Kruusel K, Kangur L, Jornvall H, Sillard R. Metal binding of metallothionein-3 versus metallothionein-2: lower affinity and higher plasticity. Biochim Biophys Acta. 2005 Mar 14;1747(2):205-11. Epub 2004 Dec 19. PMID: 15698955 [PubMed - indexed for MEDLINE]

Palumaa P., Voronova A., Kangur L., Sillard R., Meyer-Klaucke W., Meyer T., Rompel A.Mammalian copper chaperone Cox17 exists in two metalloforms, linked by oxidative switch Abstract number: G2-098P, 30th FEBS Congress - 9th IUBMB Conference, The Protein World Proteins and Peptides: Structure, Function and Organization, Budapest, Hungary 2nd-7th July, 2005

Palumaa P, Kangur L, Voronova A, Sillard R. Metal-binding mechanism of Cox17, a copper chaperone for cytochrome c oxidase. Biochem J. 2004 Aug 15;382(Pt 1):307-14. PMID: 15142040 [PubMed - indexed for MEDLINE]

Palumaa P, Eriste E, Kruusel K, Kangur L, Jornvall H, Sillard R. Metal binding to brain-specific metallothionein-3 studied by electrospray ionization mass spectrometry. Cell Mol Biol (Noisy-le-grand). 2003 Jul;49(5):763-8. PMID: 14528913 [PubMed - indexed for MEDLINE]

Nurk A, Simisker J, Kangur L, Medijainen L, Heinaru E, Heinaru A. A novel thermophilic isolate for the production of L(+)-lactate. The 9th International Symposium on the Genetics of Industrial Microorganisms Abstract book. Gyeongju, Korea 1.– 5.06 2002

Kangur L, Palumaa P. The effects of physiologically important nonmetallic ligands in the reactivity of metallothionein towards 5,5'-dithiobis(2-nitrobenzoic acid). A new method for the determination of ligand interactions with metallothionein. Eur J Biochem. 2001 Sep;268(18):4979-84. PMID: 11559367 [PubMed - indexed for MEDLINE]

Bonetto V, Kangur L, Palumaa P, Mutt V, Jornvall H, Sillard R. Large-scale HPLC purification of calbindin D9k from porcine intestine. Protein Expr Purif. 1999 Dec;17(3):387-91. PMID: 10600456 [PubMed - indexed for MEDLINE]

last updated: 06.10.2005

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