ERIS - Eesti teadus- ja arendustegevuse infosüsteem

Elulookirjeldus (CV)
1.	Eesnimi	Reet
2.	Perekonnanimi	Mändar
3.	Töökoht	Tartu Ülikool, Mikrobioloogia instituut
4.	Ametikoht	dotsent
5.	Sünniaeg	10.06.1964 (päev.kuu.aasta)
6.	Haridus	Tartu Ülikool, Arstiteaduskond, ravi eriala 1988.a., arsti kvalifikatsioon. Tartu Ülikool, meditsiinidoktor 1996.a.
7.	Teenistuskäik	1988-1990 TÜ mikrobioloogia instituudi stažöör-uurija. 1990-1996 TÜ ÜMPI aspirant/TÜ mikrobioloogia instituudi doktorant. 1991-1995 TÜ Maarjamõisa Haigla Mikrobioloogia labori arst-bakterioloog. 1993-1994 ja 1995-1997 TÜ mikrobioloogia instituudi assistent. 1997-2000 TÜ mikrobioloogia instituudi vanemassistent. Alates 2000 TÜ mikrobioloogia instituudi dotsent. 2004 (veebr-nov) TÜ mikrobioloogia instituudi juhataja.
8.	Teaduskraad	Meditsiinidoktor
9.	Teaduskraadi välja andnud asutus, aasta	Tartu Ülikool 1996
10.	Tunnustused	Eesti Vabariigi teaduspreemia 1994: Marika Mikelsaar, Anne Ormisson, Urmas Siigur, Epp Sepp, Reet Mändar, Irja Lutsar, Heili Varendi “Vastsündinu tervise mõjustamine mikrofloora kaudu”. USA Prostatiidi Fondi aastapreemia 2003 väljapaistvate teadussaavutuste eest prostatiidi uurimisel.
11.	Teadusorganisatsiooniline ja –administratiivne tegevus	American Society for Microbiology liige. Eesti Infektsionistide Seltsi asutajaliige. Eesti Meditsiinilise Mikrobioloogia Ühingu asutajaliige. ETF arstiteaduste ekspertiisikomisjonile esitatud granditaotluste ja grandi lõpparuannete retsensent. Tartu Ülikooli Mikrobioloogia instituudi juhataja 2004
12.	Juhendamisel kaitstud väitekirjad
13.	Teadustöö põhisuunad	Rasedate tupe ja amnionivedeliku mikrofloora ning selle ülekandumine vastsündinule. Gastriit ja Helicobacter pylori infektsioon. Parodontiidi etiopatogenees. Hambakaariese ja Streptococcus mutans’i levimus Eesti 3-aastaste laste hulgas. Inimorganismi laktofloora ja selle omadused. Kroonilise prostatiidi/kroonilise väikevaagnavalu sündroomi etiopatogenees ja epidemioloogia.
14.	Jooksvad grandid	2004-2007 ETF grant nr 5701 “Prostatiit: epidemioloogiline olukord Eestis, etioloogilised tegurid, patogeneesimehhanismid ja uudsed ravivõimalused". Grandi hoidja: Reet Mändar. 2004-2007 EU 6. raamprogrammi grant nr 508912 “BIODEFENCE – Rapid induction of passive immunity against weapons of bioterrorism using transformed GRAS microorganisms”. Eesti-poolne vastutav täitja: Reet Mändar.
15.	Teaduspublikatsioonid	Marcotte H, Kõll-Klais P, Hultberg A, Zhao Y, Gmür R, Mändar R, Mikelsaar M, Hammarström L. (2005). Expression of single-chain antibody against RgpA protease of Porphyromonas gingivalis in Lactobacillus. J Appl Microbiol (online early Dec 12, 2005). Kõll-Klais P, Mändar R, Leibur E, Marcotte H, Hammarström L, Mikelsaar M. (2005). Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity. Oral Microbiol Immunol 20: 354-361. Mändar R, Raukas E, Türk S, Korrovits P, Punab M. (2005). Mycoplasmas in semen of chronic prostatitis patients. Scand J Urol Nephrol 39: 479–482 Songisepp E, Kals J, Kullisaar T, Hütt P, Mändar R, Zilmer M, Mikelsaar M. (2005). Evaluation of the functional efficacy of an antioxidative probiotic in healthy volunteers. Nutr J 4: 22 Kõll-Klais P, Mändar R, Leibur E, Kjaeldgaard M. (2004). High levels of salivary lactobacilli in Estonian schoolchildren. European Journal of Paediatric Dentistry 5: 107-109. Mikelsaar M, Mändar R, Sepp E, Annuk H. (2004). Human lactic acid microflora and its role in the welfare of the host. In: Lactic Acid Bacteria. Microbiological and Functional Aspects (Eds. S Salminen, A von Wright, A Ouwehand). New York, Marcel Dekker, Inc., p. 453-506. Kermes K., Punab M., Lõivukene K., Mändar R. (2003). Anaerobic seminal fluid microflora in chronic prostatitis/chronic pelvic pain syndrome patients. Anaerobe 9: 117-123. Punab M., Lõivukene K., Kermes K., Mändar R. (2003). The limit of leukocytospermia from the microbiological viewpoint. Andrologia 35: 271-278. Mikelsaar M, Annuk H, Shchepetova J, Mändar R, Sepp E, Björksten B. (2002). Intestinal lactobacilli of Estonian and Swedish children. Microbial Ecology in Health and Disease, 14, 75-80. Mändar R, Lôivukene K, Ehrenberg A, Smidt I, Raukas E, KaskV, Mikelsaar M. (2001). Amniotic fluid microflora in asymptomatic women at mid pregnancy. Scandinavian Journal of Infectious Diseases, 33, 60-62. Mändar R, Lõivukene K, Hütt P, Karki T, Mikelsaar M. (2001). Antibacterial susceptibility of intestinal lactobacilli of healthy children. Scandinavian Journal of Infectious Diseases, 33, 344-349. Mikelsaar M, Mändar R, Sepp E. (1998). Lactic Acid Microflora in the Human Microbial Ecosystem and Its Development. In: Lactic Acid Bacteria (Eds S Salminen, A von Wright). New York, Marcel Dekker, Ltd, 279-342. Mikelsaar M, Mändar R, Maaroos H-I, Päär S, Rägo T, Kisand K, Aleljung P, Wadström T. (1996). Helicobacter pylori gastritis in children: a clinical, bacteriological, and morphological study. Microecology and Therapy, 22, 44-53. Mändar R and Mikelsaar M. (1996). Transmission of mother's microflora to the newborn at birth. Biology of the Neonate, 69, 30-35. Mändar R and Mikelsaar M. (1996). Vaginal microflora during pregnancy. Alpe Adria Microbiology Journal, 5, 41-50. Mikelsaar M, Sepp E, Mändar R, Ormisson A. (1995). Criteria for evaluation of the faecal microflora. Microecology and Therapy, 23, 149-150. Mändar R, Saag H, Peil P and Mikelsaar M. (1995). Bacterial vaginosis during pregnancy. Microecology and Therapy, 23, 24-31. Mikelsaar M and Mändar R. (1993). Development of individual lactic acid microflora in the human microbial ecosystem. In: Lactic Acid Bacteria (Eds S Salminen, A von Wright). New York, Marcel Dekker, Inc., p. 237-293.

viimati muudetud: 05.10.2005

Curriculum Vitae (CV)
1.	First Name	Reet
2.	Surname	Mändar
3.	Institution	University of Tartu, Department of Microbiology
4.	Position	associate professor
5.	Date of birth	10.06.1964 (day.month.year)
6.	Education	1988 M.D. University of Tartu, Medical Faculty, physician. 1996 Ph.D. University of Tartu.
7.	Research and professional experience	1988-1990 resident in Department of Microbiology, University of Tartu. 1990-1996 Ph.D. student in Institute of General and Molecular Pathology, and Department of Microbiology, University of Tartu. 1991-1995 doctor-bacteriologist in Tartu University Hospital. 1993-1997 assistant in Department of Microbiology, University of Tartu. 1997-2000 senior assistant in Department of Microbiology, University of Tartu. From 2000 associate professor in Department of Microbiology, University of Tartu. 2004 Feb-Nov head of Department of Microbiology, University of Tartu.
8.	Academic degree	Ph.D.
9.	Dates and sites of earning the degrees	University of Tartu 1996
10.	Honours/awards	Annual award of Committee for Scientific Awards of Estonian Republic in 1994 for medical research: Marika Mikelsaar, Anne Ormisson, Urmas Siigur, Epp Sepp, Reet Mändar, Irja Lutsar, Heili Varendi “Regulating the newborn’s health by microflora” (theoretical-clinical research in1993-1994). Award of The Prostatitis Foundation of USA for Research Excellence (for two publications devoted to chronic prostatitis) 2003.
11.	Research-administrative experience	Member of ASM (American Society for Microbiology). Referee of grant applications of Estonian Science Foundation. 2004 head of Department of Microbiology, University of Tartu.
12.	Supervised dissertations
13.	Current research program	Vaginal microflora during pregnancy and its transmission to newborn, microflora of amniotic fluid. Gastritis and Helicobacter pylori infection. Human lactoflora and its properties. Oral microecology, etiopathogenesis of chronic periodontitis. Etiology and epidemiology of chronic prostatitis.
14.	Current grant funding	Grant of Estonian Science Foundation no 5701 for 2004-2007 “Prostatitis: epidemiology in Estonia, etiological factors, mechanisms of pathogenesis and novel treatment strategies”. Grant of Commission of the European Communities no 508912 for 2004-2007 “BIODEFENCE: Rapid induction of passive immunity against weapons of bioterrorism using transformed GRAS microorganisms” (coordinator: Karolinska Institute, Sweden).
15.	List of most important publications	Marcotte H, Kõll-Klais P, Hultberg A, Zhao Y, Gmür R, Mändar R, Mikelsaar M, Hammarström L. (2005). Expression of single-chain antibody against RgpA protease of Porphyromonas gingivalis in Lactobacillus. J Appl Microbiol (online early Dec 12, 2005). Kõll-Klais P, Mändar R, Leibur E, Marcotte H, Hammarström L, Mikelsaar M. (2005). Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity. Oral Microbiol Immunol 20: 354-361. Mändar R, Raukas E, Türk S, Korrovits P, Punab M. (2005). Mycoplasmas in semen of chronic prostatitis patients. Scand J Urol Nephrol 39: 479–482 Songisepp E, Kals J, Kullisaar T, Hütt P, Mändar R, Zilmer M, Mikelsaar M. (2005). Evaluation of the functional efficacy of an antioxidative probiotic in healthy volunteers. Nutr J 4: 22 Kõll-Klais P, Mändar R, Leibur E, Kjaeldgaard M. (2004). High levels of salivary lactobacilli in Estonian schoolchildren. European Journal of Paediatric Dentistry 5: 107-109. Mikelsaar M, Mändar R, Sepp E, Annuk H. (2004). Human lactic acid microflora and its role in the welfare of the host. In: Lactic Acid Bacteria. Microbiological and Functional Aspects (Eds. S Salminen, A von Wright, A Ouwehand). New York, Marcel Dekker, Inc., p. 453-506. Kermes K., Punab M., Lõivukene K., Mändar R. (2003). Anaerobic seminal fluid microflora in chronic prostatitis/chronic pelvic pain syndrome patients. Anaerobe 9: 117-123. Punab M., Lõivukene K., Kermes K., Mändar R. (2003). The limit of leukocytospermia from the microbiological viewpoint. Andrologia 35: 271-278. Mikelsaar M, Annuk H, Shchepetova J, Mändar R, Sepp E, Björksten B. (2002). Intestinal lactobacilli of Estonian and Swedish children. Microbial Ecology in Health and Disease, 14, 75-80. Mändar R, Lôivukene K, Ehrenberg A, Smidt I, Raukas E, KaskV, Mikelsaar M. (2001). Amniotic fluid microflora in asymptomatic women at mid pregnancy. Scandinavian Journal of Infectious Diseases, 33, 60-62. Mändar R, Lõivukene K, Hütt P, Karki T, Mikelsaar M. (2001). Antibacterial susceptibility of intestinal lactobacilli of healthy children. Scandinavian Journal of Infectious Diseases, 33, 344-349. Mikelsaar M, Mändar R, Sepp E. (1998). Lactic Acid Microflora in the Human Microbial Ecosystem and Its Development. In: Lactic Acid Bacteria (Eds S Salminen, A von Wright). New York, Marcel Dekker, Ltd, 279-342. Mikelsaar M, Mändar R, Maaroos H-I, Päär S, Rägo T, Kisand K, Aleljung P, Wadström T. (1996). Helicobacter pylori gastritis in children: a clinical, bacteriological, and morphological study. Microecology and Therapy, 22, 44-53. Mändar R and Mikelsaar M. (1996). Transmission of mother's microflora to the newborn at birth. Biology of the Neonate, 69, 30-35. Mändar R and Mikelsaar M. (1996). Vaginal microflora during pregnancy. Alpe Adria Microbiology Journal, 5, 41-50. Mikelsaar M, Sepp E, Mändar R, Ormisson A. (1995). Criteria for evaluation of the faecal microflora. Microecology and Therapy, 23, 149-150. Mändar R, Saag H, Peil P and Mikelsaar M. (1995). Bacterial vaginosis during pregnancy. Microecology and Therapy, 23, 24-31. Mikelsaar M and Mändar R. (1993). Development of individual lactic acid microflora in the human microbial ecosystem. In: Lactic Acid Bacteria (Eds S Salminen, A von Wright). New York, Marcel Dekker, Inc., p. 237-293.

last updated: 05.10.2005