[ sulge aken ]
| Elulookirjeldus (CV) | ||
| 1. | Eesnimi | Rita |
| 2. | Perekonnanimi | Hõrak |
| 3. | Töökoht | Eesti Biokeskus |
| 4. | Ametikoht | vanemteadur |
| 5. | Sünniaeg | 16.11.1962 (päev.kuu.aasta) |
| 6. | Haridus | Tartu Ülikool (1982-1987), bioloogia-geograafiateaduskond, biokeemia |
| 7. | Teenistuskäik | 1987-1997 - Eesti Biokeskus, nooremteadur 1997-2002 - Eesti Biokeskus, teadur alates 2002 - Eesti Biokeskus, vanemteadur |
| 8. | Teaduskraad | PhD |
| 9. | Teaduskraadi välja andnud asutus, aasta |
Tartu Ülikool, 2002 |
| 10. | Tunnustused | |
| 11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
Eesti Mikrobioloogide Ühenduse liige |
| 12. | Juhendamisel kaitstud väitekirjad |
Heili Ilves, MSc, 2001, juh. Rita Hõrak. Pseudomonas putida transposooni Tn4652 transpositsiooni regulatsioon. Tartu Ülikool |
| 13. | Teadustöö põhisuunad | 1. Transpositsiooni regulatsioon bakterites 2. Bakteriraku membraani permeaabluse regulatsioon |
| 14. | Jooksvad grandid | ETF-i grant nr. 6025: "ColR-ColS kahekomponendilise signaaliraja roll bakterite geneetilises kohastumises keskkonnaga" |
| 15. | Teaduspublikatsioonid |
Tark, M., Tover, A., Tarassova, K., Tegova, R., Kivi, G., Horak, R. and Kivisaar, M. (2005) A DNA polymerase V homologue encoded by TOL plasmid pWW0 confers evolutionary fitness on Pseudomonas putida under conditions of environmental stress. J Bacteriol 187: 5203-13. Hõrak, R., Ilves, H., Pruunsild, P., Kuljus, M. and Kivisaar, M. (2004) The ColR-ColS two-component signal transduction system is involved in regulation of Tn4652 transposition in Pseudomonas putida under starvation conditions. Mol Microbiol 54: 795-807. Ilves, H., Hõrak, R., Teras, R. and Kivisaar, M. (2004) IHF is the limiting host factor in transposition of Pseudomonas putida transposon Tn4652 in stationary phase. Mol Microbiol 51: 1773-85. Ilves, H., Hõrak, R. and Kivisaar, M. (2001) Involvement of sigma(S) in starvation-induced transposition of Pseudomonas putida transposon Tn4652. J Bacteriol 183: 5445-8. Teras, R., Hõrak, R. and Kivisaar, M. (2000) Transcription from fusion promoters generated during transposition of transposon Tn4652 is positively affected by integration host factor in Pseudomonas putida. J Bacteriol 182: 589-598. Hõrak, R. and Kivisaar, M. (1999) Regulation of the transposase of Tn4652 by the transposon-encoded protein TnpC. J Bacteriol 181: 6312-6318. Hõrak, R. and Kivisaar, M. (1998) Expression of the transposase gene tnpA of Tn4652 is positively affected by integration host factor. J Bacteriol 180: 2822-9. Kallastu, A., Hõrak, R. and Kivisaar, M. (1998) Identification and characterization of IS1411, a new insertion sequence which causes transcriptional activation of the phenol degradation genes in Pseudomonas putida. J Bacteriol 180: 5306-12. Kasak, L., Hõrak, R. and Kivisaar, M. (1997) Promoter-creating mutations in Pseudomonas putida: a model system for the study of mutation in starving bacteria. Proc Natl Acad Sci U S A 94: 3134-9. Kasak, L., Hõrak, R., Nurk, A., Talvik, K. and Kivisaar, M. (1993) Regulation of the catechol 1,2-dioxygenase- and phenol monooxygenase- encoding pheBA operon in Pseudomonas putida PaW85. J Bacteriol 175: 8038-42. Nurk, A., Tamm, A., Hõrak, R. and Kivisaar, M. (1993) In-vivo-generated fusion promoters in Pseudomonas putida. Gene 127: 23-9. Kivisaar, M., Hõrak, R., Kasak, L., Heinaru, A. and Habicht, J. (1990) Selection of independent plasmids determining phenol degradation in Pseudomonas putida and the cloning and expression of genes encoding phenol monooxygenase and catechol 1,2-dioxygenase. Plasmid 24: 25-36. |
viimati muudetud: 05.10.2005
| Curriculum Vitae (CV) | ||
| 1. | First Name | Rita |
| 2. | Surname | Hõrak |
| 3. | Institution | Estonian Biocentre |
| 4. | Position | senior research associate |
| 5. | Date of birth | 16.11.1962 (day.month.year) |
| 6. | Education | Tartu University (1982-1987), Faculty of Biology and Geography, biochemist |
| 7. | Research and professional experience |
1987-1997 - Estonian Biocentre, junior research scientist 1997-2002 - Estonian Biocentre, research scientist since 2002 - Estonian Biocentre, senior research scientist |
| 8. | Academic degree | PhD |
| 9. | Dates and sites of earning the degrees |
Tartu University, 2002 |
| 10. | Honours/awards | |
| 11. | Research-administrative experience |
Member of Estonian Society for Microbiology |
| 12. | Supervised dissertations |
Heili Ilves, MSc, 2001, superv. Rita Hõrak. Pseudomonas putida transposooni Tn4652 transpositsiooni regulatsioon. Tartu Ülikool |
| 13. | Current research program | 1. Regulation of transposition in microbes 2. Regulation of bacterial membrane permeability |
| 14. | Current grant funding | Grant 6025 from Estonian Science Foundation: "ColR-ColS signal transduction system regulating genetic adaptation of bacteria" |
| 15. | List of most important publications |
Tark, M., Tover, A., Tarassova, K., Tegova, R., Kivi, G., Horak, R. and Kivisaar, M. (2005) A DNA polymerase V homologue encoded by TOL plasmid pWW0 confers evolutionary fitness on Pseudomonas putida under conditions of environmental stress. J Bacteriol 187: 5203-13. Hõrak, R., Ilves, H., Pruunsild, P., Kuljus, M. and Kivisaar, M. (2004) The ColR-ColS two-component signal transduction system is involved in regulation of Tn4652 transposition in Pseudomonas putida under starvation conditions. Mol Microbiol 54: 795-807. Ilves, H., Hõrak, R., Teras, R. and Kivisaar, M. (2004) IHF is the limiting host factor in transposition of Pseudomonas putida transposon Tn4652 in stationary phase. Mol Microbiol 51: 1773-85. Ilves, H., Hõrak, R. and Kivisaar, M. (2001) Involvement of sigma(S) in starvation-induced transposition of Pseudomonas putida transposon Tn4652. J Bacteriol 183: 5445-8. Teras, R., Hõrak, R. and Kivisaar, M. (2000) Transcription from fusion promoters generated during transposition of transposon Tn4652 is positively affected by integration host factor in Pseudomonas putida. J Bacteriol 182: 589-598. Hõrak, R. and Kivisaar, M. (1999) Regulation of the transposase of Tn4652 by the transposon-encoded protein TnpC. J Bacteriol 181: 6312-6318. Hõrak, R. and Kivisaar, M. (1998) Expression of the transposase gene tnpA of Tn4652 is positively affected by integration host factor. J Bacteriol 180: 2822-9. Kallastu, A., Hõrak, R. and Kivisaar, M. (1998) Identification and characterization of IS1411, a new insertion sequence which causes transcriptional activation of the phenol degradation genes in Pseudomonas putida. J Bacteriol 180: 5306-12. Kasak, L., Hõrak, R. and Kivisaar, M. (1997) Promoter-creating mutations in Pseudomonas putida: a model system for the study of mutation in starving bacteria. Proc Natl Acad Sci U S A 94: 3134-9. Kasak, L., Hõrak, R., Nurk, A., Talvik, K. and Kivisaar, M. (1993) Regulation of the catechol 1,2-dioxygenase- and phenol monooxygenase- encoding pheBA operon in Pseudomonas putida PaW85. J Bacteriol 175: 8038-42. Nurk, A., Tamm, A., Hõrak, R. and Kivisaar, M. (1993) In-vivo-generated fusion promoters in Pseudomonas putida. Gene 127: 23-9. Kivisaar, M., Hõrak, R., Kasak, L., Heinaru, A. and Habicht, J. (1990) Selection of independent plasmids determining phenol degradation in Pseudomonas putida and the cloning and expression of genes encoding phenol monooxygenase and catechol 1,2-dioxygenase. Plasmid 24: 25-36. |
last updated: 05.10.2005
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