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Elulookirjeldus (CV) | ||
1. | Eesnimi | Tiina |
2. | Perekonnanimi | Sedman |
3. | Töökoht | Tartu Ülikool, Molekulaar ja Rakubioloogia Instituut, üldise-ja mikroobibiokeemia õppetool |
4. | Ametikoht | teadur |
5. | Sünniaeg | 09.12.1959 (päev.kuu.aasta) |
6. | Haridus | bioloogia (mikrobioloogia) TRÜ |
7. | Teenistuskäik | 1989-1992 Tartu Ülikool, vanemlaborant molekuaarbioloogia osakonnas 1992-1996 Cold Spring Harbor laboratoorium, USA, tehnik dr. Arne Stenlundi laboratooriumis 2000-2001 Eesti Biokeskus, teadur 2002- Tartu Ülikool, Molekulaar ja Rakubioloogia Instituut, teadur üldise ja mikroobibiokeemia õppetoolis |
8. | Teaduskraad | MSc molekulaarbioloogias Planeeritud PhD 21.10 2005 |
9. | Teaduskraadi välja andnud asutus, aasta |
Tartu Ülikool aastal 2000 Tartu Ülikool 21.10 2005 |
10. | Tunnustused | |
11. | Teadusorganisatsiooniline ja –administratiivne tegevus |
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12. | Juhendamisel kaitstud väitekirjad |
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13. | Teadustöö põhisuunad | Olen uurinud pagaripärmi S. cerevisiae mitokondriaalse DNA stabiilsust tagavaid protsesse, ning nendes protsessides osalevaid valke. Peamisteks uurimisobjektiks on olnud mitokondriaalne DNA helikaas Hmi1. |
14. | Jooksvad grandid | |
15. | Teaduspublikatsioonid |
Kuusk, S., Sedman, T., Joers, P. and Sedman, J. (2005). Hmi1p from Saccharomyces cerevisiae mitochondria is a structure specific DNA helicase. J Biol Chem. 280, 24322-9. Sedman T., Joers P., Kuusk S., Sedman J (2005) Helicase Hmi1 stimulates the synthesis of concatemeric mitochondrial DNA molecules in yeast Saccharomyces cerevisiae. Curr Genet. 47, 213-22. Kuusk S., Sedman T., Sedman J. (2002) Recombinant yeast mtDNA helicases: purification and functional assays. Methods Mol Biol. 197, 303-16. Mitochondrial DNA. Methods and Protocols, edited by William C. Copeland, 2002. Sedman T., Kuusk S., Kivi S., Sedman J. (2000) A DNA Helicase Required for Maintenance of the Functional Mitochondrial Genome in Saccharomyces cerevisiae. Mol Cell Biol. 20, 1816-24. Kurg R., Parik J., Juronen E., Sedman T., Abroi A., Liiv I., Langel Ü., Ustav M. (1999) Effect of Bovine Papillomavirus E2 Protein-Specific Monoclonal Antibodies on Papillomavirus DNA Replication. J.Virol. 73, 4670-77 Sedman T., Sedman J. and Stenlund, A. (1997) Binding of the E1 and E2 proteins to the origin of the bovine papillomavirus. J. Virol. 71, 2887-96. |
viimati muudetud: 09.10.2005
Curriculum Vitae (CV) | ||
1. | First Name | Tiina |
2. | Surname | Sedman |
3. | Institution | Tartu University, Institute of Molecular and Cell Biology, Department of General and Microbial Biochemistry |
4. | Position | research scientist |
5. | Date of birth | 09.12.1959 (day.month.year) |
6. | Education | biology (microbiology) Tartu State University |
7. | Research and professional experience |
1989-1992 laboratory technician in Tartu University, Department of Molecular biology 1992-1996 research technician at Cold Spring Harbor Laboratory, USA 2000-2001 research scientist in Estonian Biocentre Since 2002 research scientist in Tartu University, Institute of Molecular and Cell Biology, Department of General and Microbial Biochemistry |
8. | Academic degree | MSc, molecular biology PhD defence on 21.10.2005 |
9. | Dates and sites of earning the degrees |
Tartu University, year 2000 Tartu University, on 21.10 2005 |
10. | Honours/awards | |
11. | Research-administrative experience |
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12. | Supervised dissertations | |
13. | Current research program | I am studing nuclear factors that control maintenance and integrity the of yeast S. cerevisiae mitochondrial DNA. My main research subject has been the mitochondrial DNA helicase Hmi1. |
14. | Current grant funding | |
15. | List of most important publications |
Kuusk, S., Sedman, T., Joers, P. and Sedman, J. (2005). Hmi1p from Saccharomyces cerevisiae mitochondria is a structure specific DNA helicase. J Biol Chem. 280, 24322-9. Sedman T., Joers P., Kuusk S., Sedman J (2005) Helicase Hmi1 stimulates the synthesis of concatemeric mitochondrial DNA molecules in yeast Saccharomyces cerevisiae. Curr Genet. 47, 213-22. Kuusk S., Sedman T., Sedman J. (2002) Recombinant yeast mtDNA helicases: purification and functional assays. Methods Mol Biol. 197, 303-16. Mitochondrial DNA. Methods and Protocols, edited by William C. Copeland, 2002. Sedman T., Kuusk S., Kivi S., Sedman J. (2000) A DNA Helicase Required for Maintenance of the Functional Mitochondrial Genome in Saccharomyces cerevisiae. Mol Cell Biol. 20, 1816-24. Kurg R., Parik J., Juronen E., Sedman T., Abroi A., Liiv I., Langel Ü., Ustav M. (1999) Effect of Bovine Papillomavirus E2 Protein-Specific Monoclonal Antibodies on Papillomavirus DNA Replication. J.Virol. 73, 4670-77 Sedman T., Sedman J. and Stenlund, A. (1997) Binding of the E1 and E2 proteins to the origin of the bovine papillomavirus. J. Virol. 71, 2887-96. |
last updated: 09.10.2005
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