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Elulookirjeldus (CV)
1.Eesnimi Anne
2.Perekonnanimi Kuusksalu
3.Töökoht Keemilise ja Bioloogilise Füüsika Instituut
4.Ametikoht vanemteadur
5.Sünniaeg 26.07.1959 (päev.kuu.aasta)
6.Haridus Tartu Riiklik Ülikool, füüsika-keemiateaduskond, 1982
7.Teenistuskäik 1982-1986 Eksperimentaalbioloogia Instituut, molekulaarbioloogia labor, nooremteadur
1986-2004 Keemilise ja Bioloogilise Füüsika Instituut, molekulaargeneetika labor, teadur
2004 – vanemteadur, samas
8.Teaduskraad Ph.D.
9.Teaduskraadi välja
andnud asutus, aasta
Tallinna Tehnikaülikool, 2003
10.Tunnustused -
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
-
12.Juhendamisel kaitstud
väitekirjad

Mailis Päri, PhD, 2005, juh. Anne Kuusksalu, Annika Lopp. Merekäsnast Geodia cydonium kloneeritud 2-5A süntetaasi ekspresseerimine ja iseloomustamine. Tallinna Tehnikaülikool

13.Teadustöö põhisuunad Loomse organismi molekulaarsete kaitsemehhanismide ensüümid, nende rollide mitmekesisus ja geeniregulatsioon
14.Jooksvad grandid 1. ETF nr. 5932 (2004-2007): Adenosiiniderivaatide ebatraditsioonilised signaalrajad alamates loomades
2. EC FP6 Project No. 017800 (2005-2006) Sustainable production, Physiology, Oceanography, Natural products, Genetics and Economics of Sponges (SPONGE)
3. EC Marie Curie Research Training Network MRTN-CT-2004-512301 (2005- 2008): Cope with the Challenges and Opportunities of the 21st Century: Integrated Basic and Applied Training in a Success-oriented Bioprospecting (BIOCAPITAL)
15.Teaduspublikatsioonid

A. Lopp, T. Reintamm, A. Kuusksalu, S. De Rosa, M. Kelve. Non-traditional enzymatic pathway of ATP utilization by the marine sponge Tedania sp. Proceedings of the XI International Symposium on Marine Natural Products, Sorrento, Italy, Sept. 4th-9th, 2004, P65.

M. Kelve, A. Lopp, T. Reintamm, A. Kuusksalu, G. Van de Vyver, E. Richelle-Maurer. Freshwater sponge cell cultures as model systems for biochemical pathways present in marine sponges. Aquaculture Europe 2004 Conference “Biotechnologies for quality”, Barcelona, Spain, Oct. 20-23, 2004. EAS (European Aquaculture Society) Special Publication No. 34.

Kelve, M., Kuusksalu, A., Lopp, A., Reintamm, T. (2003) Sponge (2’,5’)oligoadenylate synthetase activity in the whole sponge organism and in a primary cell culture. J. Biotechnol. 100, 177-180

Reintamm, T., Lopp, A., Kuusksalu, A., Pehk, T., Kelve, M. (2003) ATP N-glycosidase – a novel ATP converting activity from marine sponge Axinella polypoides. Eur. J. Biochem. 270, 4122-4132

Reintamm, T., Lopp, A., Kuusksalu, A., Subbi, J., Kelve, M. (2003) Qualitative and quantitative aspects of 2-5A synthesizing capacity of different marine sponges. Biomol. Engimeering 20, 389-399

Grebenjuk, V.A., Kuusksalu, A., Kelve, M., Schütze, J., Schröder, H.C., Müller, W.E.G. (2002) Induction of (2’-5’)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide. Eur. J. Biochem. 269, 1-11

Lopp, A., Kuusksalu, A., Reintamm, T., Müller, W.E.G., Kelve, M. (2002) 2’,5’-oligoadenylate sunthetase from a lower invertebrate, the marine sponge Geodia cydonium, does not need dsRNA for its enzymatic activity. Biochim. Biophys. Acta 1590, 140-149

Lopp, A., Kuusksalu, A., Samuel, K., Kelve, M. (2000) Expression and activity of 2-5A synthetase in the course of differentiation and apoptosis of PC12 cells. Cytokine 12, 737-741

viimati muudetud: 12.10.2005

Curriculum Vitae (CV)
1.First Name Anne
2.Surname Kuusksalu
3.Institution National Institute of Chemical Physics and Biophysics
4.Position senior research scientist
5.Date of birth 26.07.1959 (day.month.year)
6.Education Tartu State University, department of physics and chemistry, 1982
7.Research and
professional experience
1982-1986 Institute of Experimental Biology, laboratory of molecular biology, research scientist
1986-2004 National Institute of Chemical Physics and Biophysics (NICPB), laboratory of molecular genetics, research scientist
2004 - NICPB, senior research scientist
8.Academic degree Ph.D.
9.Dates and sites of
earning the degrees
Tallinn University of Technology, 2003
10.Honours/awards -
11.Research-administrative
experience
-
12.Supervised dissertations

Mailis Päri, PhD, 2005, superv. Anne Kuusksalu, Annika Lopp. Merekäsnast Geodia cydonium kloneeritud 2-5A süntetaasi ekspresseerimine ja iseloomustamine. Tallinna Tehnikaülikool

13.Current research program Enzymes involved in animal molecular defence mechanisms, the diversity of their roles and gene regulation
14.Current grant funding 1. ESF No. 5932 (2004-2007): Non-traditional cellular signaling of adenosine derivatives in lower animals
2. EC FP6 Project No. 017800 (2005-2006): Sustainable production, Physiology, Oceanography, Natural products, Genetics and Economics of Sponges (SPONGE)
3. EC Marie Curie Research Training Network MRTN-CT-2004-512301 (2005- 2008): Cope with the Challenges and Opportunities of the 21st Century: Integrated Basic and Applied Training in a Success-oriented Bioprospecting (BIOCAPITAL)
15.List of most important publications

A. Lopp, T. Reintamm, A. Kuusksalu, S. De Rosa, M. Kelve. Non-traditional enzymatic pathway of ATP utilization by the marine sponge Tedania sp. Proceedings of the XI International Symposium on Marine Natural Products, Sorrento, Italy, Sept. 4th-9th, 2004, P65.

M. Kelve, A. Lopp, T. Reintamm, A. Kuusksalu, G. Van de Vyver, E. Richelle-Maurer. Freshwater sponge cell cultures as model systems for biochemical pathways present in marine sponges. Aquaculture Europe 2004 Conference “Biotechnologies for quality”, Barcelona, Spain, Oct. 20-23, 2004. EAS (European Aquaculture Society) Special Publication No. 34.

Kelve, M., Kuusksalu, A., Lopp, A., Reintamm, T. (2003) Sponge (2’,5’)oligoadenylate synthetase activity in the whole sponge organism and in a primary cell culture. J. Biotechnol. 100, 177-180

Reintamm, T., Lopp, A., Kuusksalu, A., Pehk, T., Kelve, M. (2003) ATP N-glycosidase – a novel ATP converting activity from marine sponge Axinella polypoides. Eur. J. Biochem. 270, 4122-4132

Reintamm, T., Lopp, A., Kuusksalu, A., Subbi, J., Kelve, M. (2003) Qualitative and quantitative aspects of 2-5A synthesizing capacity of different marine sponges. Biomol. Engimeering 20, 389-399

Grebenjuk, V.A., Kuusksalu, A., Kelve, M., Schütze, J., Schröder, H.C., Müller, W.E.G. (2002) Induction of (2’-5’)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide. Eur. J. Biochem. 269, 1-11

Lopp, A., Kuusksalu, A., Reintamm, T., Müller, W.E.G., Kelve, M. (2002) 2’,5’-oligoadenylate sunthetase from a lower invertebrate, the marine sponge Geodia cydonium, does not need dsRNA for its enzymatic activity. Biochim. Biophys. Acta 1590, 140-149

Lopp, A., Kuusksalu, A., Samuel, K., Kelve, M. (2000) Expression and activity of 2-5A synthetase in the course of differentiation and apoptosis of PC12 cells. Cytokine 12, 737-741

last updated: 12.10.2005

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