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Elulookirjeldus (CV)
1.Eesnimi Annika
2.Perekonnanimi Lopp
3.Töökoht Keemilise ja Bioloogilise Füüsika Instituut
4.Ametikoht vanemteadur
5.Sünniaeg 06.06.1948 (päev.kuu.aasta)
6.Haridus 1971 Tartu Riiklik Ülikool, orgaaniline keemia
1971-1974 TA Keemia Instituut, aspirantuur
7.Teenistuskäik 1974-1982 TA Keemia Instituut, nooremteadur
1982-1995 TA Keemia Instituut, vanemteadur
1995- Keemilise ja Bioloogilise Füüsika Instituut, vanemteadur
8.Teaduskraad bioloogiakandidaat (eriala: onkoloogia)
9.Teaduskraadi välja
andnud asutus, aasta		 Üleliiduline Onkoloogiakeskus, Moskva, 1979
10.Tunnustused -
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus		 -
12.Juhendamisel kaitstud
väitekirjad

Mailis Päri, MSc, 2005, juh. Anne Kuusksalu, Annika Lopp. Merekäsnast Geodia cydonium kloneeritud 2-5A süntetaasi ekspresseerimine ja iseloomustamine. TTÜ, Matemaatika-loodusteaduskond, Geenitehnoloogia Instituut
13.Teadustöö põhisuunad Loomse organismi molekulaarsete kaitsemehhanismide ensüümid, nende rollide mitmekesisus ja geeniregulatsioon
14.Jooksvad grandid 1. ETF nr. 5932 (2004-2007): Adenosiiniderivaatide ebatraditsioonilised signaalrajad alamates loomades
2. EC FP6 Project No. 017800 (2005-2006): Sustainable production, Physiology, Oceanography, Natural products, Genetics and Economics of Sponges (SPONGE)
3. EC Marie Curie Research Training Network MRTN-CT-2004-512301 (2005-2008): Cope with the Challenges and Opportunities of the 21st Century: Integrated Basic and Applied Training in a Success-oriented Bioprospecting (BIOCAPITAL)
15.Teaduspublikatsioonid

Trummal, K., Tõnismägi, K., Siigur, E., Aaspõllu, A., Lopp, A., Sillat, T., Saat, R., Kasak, L., Tammiste, I., Kogerman, P., Kalkkinen, N., Siigur, J. (2005) A novel metalloprotease from Vipera lebetina venom induces human endothelial cell apoptosis. Toxicon 46, 46-61.

Kelve, M., Kuusksalu, A., Lopp, A., Reintamm, T. (2003) Sponge (2’,5’)oligoadenylate synthetase activity in the whole sponge organism and in a primary cell culture. J. Biotechnology 100, 177-180.

Reintamm, T., Lopp, A., Kuusksalu, A., Pehk, T., Kelve, M. (2003) ATP N-glycosidase. A novel ATP-converting activity from a marine sponge Axinella polypoides. Eur. J. Biochem. 270, 4122-4133.

Reintamm, T., Lopp, A., Kuusksalu, A., Subbi, J., Kelve, M. (2003) Qualitative and quantitative aspects of 2-5A synthesizing capacity of different marine sponges. Biomol. Engineering 20, 389-399.

Lopp, A., Kuusksalu, A., Reintamm, T., Müller, W.E.G., Kelve, M. (2002) 2’,5’-oligoadenylate synthetase from a lower invertebrate, the marine sponge Geodia cydonium, does not need dsRNA for its enzymatic activity. Biochim. Biophys. Acta 1590, 140-149.

Lopp, A., Kuusksalu, A., Samuel, K., Kelve, M. (2000) Expression and activity of 2-5A synthetase in the course of differentiation and apoptosis of PC12 cells. Cytokine 12, 737-741.

viimati muudetud: 13.10.2005

Curriculum Vitae (CV)
1.First Name Annika
2.Surname Lopp
3.Institution National Institute of Chemical Physics and Biophysics
4.Position senior research scientist
5.Date of birth 06.06.1948 (day.month.year)
6.Education 1971 Tartu State University, organic chemistry
1971-1974 Institute of Chemistry of the Academy of Sciences, post-graduate studies
7.Research and
professional experience		 1974-1982 Institute of Chemistry, research scientist
1982-1995 Institute of Chemistry, senior research scientist
1995- Institute of Chemical Physics and Biophysics, senior research scientist
8.Academic degree candidate in biology (speciality: oncology)
9.Dates and sites of
earning the degrees		 All-Union Research Center in Oncology, Moscow, 1979
10.Honours/awards -
11.Research-administrative
experience		 -
12.Supervised dissertations

Mailis Päri, MSc, 2005, superv. Anne Kuusksalu, Annika Lopp. Merekäsnast Geodia cydonium kloneeritud 2-5A süntetaasi ekspresseerimine ja iseloomustamine. TTÜ, Matemaatika-loodusteaduskond, Geenitehnoloogia Instituut
13.Current research program Enzymes involved in animal molecular defence mechanisms, the diversity of their roles and gene regulation
14.Current grant funding 1. ESF No. 5932 (2004-2007): Non-traditional cellular signaling of adenosine derivatives in lower animals
2. EC FP6 Project No. 017800 (2005-2006): Sustainable production, Physiology, Oceanography, Natural products, Genetics and Economics of Sponges (SPONGE)
3. EC Marie Curie Research Training Network MRTN-CT-2004-512301 (2005-2008): Cope with the Challenges and Opportunities of the 21st Century: Integrated Basic and Applied Training in a Success-oriented Bioprospecting (BIOCAPITAL)
15.List of most important publications

Trummal, K., Tõnismägi, K., Siigur, E., Aaspõllu, A., Lopp, A., Sillat, T., Saat, R., Kasak, L., Tammiste, I., Kogerman, P., Kalkkinen, N., Siigur, J. (2005) A novel metalloprotease from Vipera lebetina venom induces human endothelial cell apoptosis. Toxicon 46, 46-61.

Kelve, M., Kuusksalu, A., Lopp, A., Reintamm, T. (2003) Sponge (2’,5’)oligoadenylate synthetase activity in the whole sponge organism and in a primary cell culture. J. Biotechnology 100, 177-180.

Reintamm, T., Lopp, A., Kuusksalu, A., Pehk, T., Kelve, M. (2003) ATP N-glycosidase. A novel ATP-converting activity from a marine sponge Axinella polypoides. Eur. J. Biochem. 270, 4122-4133.

Reintamm, T., Lopp, A., Kuusksalu, A., Subbi, J., Kelve, M. (2003) Qualitative and quantitative aspects of 2-5A synthesizing capacity of different marine sponges. Biomol. Engineering 20, 389-399.

Lopp, A., Kuusksalu, A., Reintamm, T., Müller, W.E.G., Kelve, M. (2002) 2’,5’-oligoadenylate synthetase from a lower invertebrate, the marine sponge Geodia cydonium, does not need dsRNA for its enzymatic activity. Biochim. Biophys. Acta 1590, 140-149.

Lopp, A., Kuusksalu, A., Samuel, K., Kelve, M. (2000) Expression and activity of 2-5A synthetase in the course of differentiation and apoptosis of PC12 cells. Cytokine 12, 737-741.

last updated: 13.10.2005

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