ERIS - Eesti teadus- ja arendustegevuse infosüsteem

Elulookirjeldus (CV)
1.	Eesnimi	Krista
2.	Perekonnanimi	Kaasik
3.	Töökoht	TÜ MRI, Biotehnoloogia õppetool
4.	Ametikoht	teadur
5.	Sünniaeg	02.02.1974 (päev.kuu.aasta)
6.	Haridus	2005 - Ph.D. kraad, TÜ 1999 - teadusmagistri kraad TÜ 1997 - bakalaureause kraad TÜ
7.	Teenistuskäik	2000-2005 TÜMRI doktorant 2000-2003 külalisüliõpilane Baylor College of Medicine, Houston, Texas, USA 2001- teadustöötaja Max Planck Institute, Hannover. Saksamaa 1999-2000 teadustöötaja Rockefeller University, New York, USA 1999-teadustöötaja Cambridge University, Inglismaa 1998-Stockholmi University (Rootsi) teadustöö 1995-1999 TUMRI magistrand
8.	Teaduskraad	M.Sc. - TÜ MRI 1999
9.	Teaduskraadi välja andnud asutus, aasta	Ph.D. - TÜ MRI 2005
10.	Tunnustused	2000 - Keystone stipendium 1998 - European Union TEMPUS Fellowship 1997 - Revelia stipendium
11.	Teadusorganisatsiooniline ja –administratiivne tegevus	AAAS liige
12.	Juhendamisel kaitstud väitekirjad
13.	Teadustöö põhisuunad	Imetajate 24 tunni rütmide molekulaarne analüüs, uute kella geenide kirjeldamine ja nende molekulaar-geneetiline analüüs.Tsirkaadse kella ja heemi biosünteesi omavaheline regulatsioon.
14.	Jooksvad grandid
15.	Teaduspublikatsioonid	Kaasik K and Lee CC. Reciprocal regulation of haem biosynthesis and the circadian clock in mammals. Nature. 2004 Jul 22; 430(6998): 467-71. Walz K, Spencer C, Kaasik K, Lee CC, Lupski JR, Paylor R. Behavioral characterization of mouse models for Smith-Magenis syndrome and dup(17)(p11.2p11.2). Hum Mol Genet. 2004 Feb 15;13(4):367-78. Greenfield JP, Leung LW, Cai D, Kaasik K, Gross RS, Rodriguez-Boulan E, Greengard P, Xu H. Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis. J Biol Chem. 2002 Apr 5;277(14):12128-36. Zheng B, Albrecht U, Kaasik K, Sage M, Lu W, Vaishnav S, Li Q, Sun ZS, Eichele G, Bradley A, Lee CC. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell. 2001 Jun 1;105(5):683-94. Teder M, Klaassen T, Oitmaa E, Kaasik K, Metspalu A. Distribution of CFTR gene mutations in cystic fibrosis patients from Estonia. J Med Genet. 2000 Aug;37(8):E16. Tonisson N, Kurg A, Kaasik K, Lohmussaar E, Metspalu A. Unravelling genetic data by arrayed primer extension. Clin Chem Lab Med. 2000 Feb;38(2):165-70.

viimati muudetud: 19.10.2005

Curriculum Vitae (CV)
1.	First Name	Krista
2.	Surname	Kaasik
3.	Institution	University of Tartu, Institute of Molecular and Cell Biology, Dept. of Biotechnology
4.	Position	Research Fellow
5.	Date of birth	02.02.1974 (day.month.year)
6.	Education	2005 - Ph.D. degree in Molecular Biomedicine, Tartu University, Estonia 1999 - Cum laude graduation with MSc degree in Biotechnology, Tartu University, Estonia 1997 - Bachelor degree in Molecular Biology and Genetics from Tartu University, Estonia
7.	Research and professional experience	2001 - Research Trainee in Max Planck Institute, Hannover, Germany, in the laboratory of Dr. Urs Albrecht. Research on circadian rhythms. 1999 - 2000 Research Intern in Dr. Huaxi Xu’s group in Dr. Paul Greengard’s laboratory (2000 Nobel Laureate in Physiology & Medicine) at the Rockefeller University. New York, USA. Research on Alzheimer disease. 1999 - Research Intern in CRC Department of Oncology, Strangeways Research Center Cambridge, UK, in the laboratory of Dr. Simon Gayther. Research on breast cancer. 1998 - TEMPUS Program Fellow in Department of Neurochemistry and Neurotoxicology Arrhenius Natural Science Laboratories, Stockholm University, Sweden, in the laboratory of Dr. Kerstin Iverfeldt. Research on Alzheimer disease. 1997 - Laboratoire de Biochemie Genetique, Institute de Biologie Montpellier, France in the laboratory of Dr. Marie Claustre. Research on Cystic Fibrosis. 1995-1997 - Institute of Molecular and Cell Biology, Tartu, Estonia. Research on Cystic Fibrosis.
8.	Academic degree	Cum laude graduation with MSc degree in Biotechnology, Tartu University, Estonia - 1999
9.	Dates and sites of earning the degrees	Ph.D. degree in Molecular Biomedicine, Tartu University, Estonia - 2005
10.	Honours/awards	2000 - Keystone schloarship 1998 - European Union TEMPUS Fellowship 1997 - Revelia Scholarship at Tartu University, Estonia
11.	Research-administrative experience	AAAS Member
12.	Supervised dissertations
13.	Current research program	Circadian clock genes. Reciprocal regulation of haem biosynthesis and the circadian clock in mammals.
14.	Current grant funding
15.	List of most important publications	Kaasik K and Lee CC. Reciprocal regulation of haem biosynthesis and the circadian clock in mammals. Nature. 2004 Jul 22; 430(6998): 467-71. Walz K, Spencer C, Kaasik K, Lee CC, Lupski JR, Paylor R. Behavioral characterization of mouse models for Smith-Magenis syndrome and dup(17)(p11.2p11.2). Hum Mol Genet. 2004 Feb 15;13(4):367-78. Greenfield JP, Leung LW, Cai D, Kaasik K, Gross RS, Rodriguez-Boulan E, Greengard P, Xu H. Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis. J Biol Chem. 2002 Apr 5;277(14):12128-36. Zheng B, Albrecht U, Kaasik K, Sage M, Lu W, Vaishnav S, Li Q, Sun ZS, Eichele G, Bradley A, Lee CC. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell. 2001 Jun 1;105(5):683-94. Teder M, Klaassen T, Oitmaa E, Kaasik K, Metspalu A. Distribution of CFTR gene mutations in cystic fibrosis patients from Estonia. J Med Genet. 2000 Aug;37(8):E16. Tonisson N, Kurg A, Kaasik K, Lohmussaar E, Metspalu A. Unravelling genetic data by arrayed primer extension. Clin Chem Lab Med. 2000 Feb;38(2):165-70.

last updated: 19.10.2005