ERIS - Eesti teadus- ja arendustegevuse infosüsteem

Elulookirjeldus (CV)
1.	Eesnimi	Lembi
2.	Perekonnanimi	Kogerman
3.	Töökoht	Keemilise ja Bioloogilise Füüsika Instituut
4.	Ametikoht	vaneminsener
5.	Sünniaeg	28.04.1966 (päev.kuu.aasta)
6.	Haridus	Tartu Ülikool, bioloogia ja keemia
7.	Teenistuskäik	1987-90: laborant (osalise tööajaga), 1993: tehnik (osalise tööajaga) United States Biochemical, sekveneerimise teenistus, Cleveland, Ohio 1993-97: uurimisassistent, Case Western Reserve Ülikool, Molekulaar- ja Mikrobioloogia ning Pediaatria Osakonnad 1997-99: uurimisassistent/doktorand, Karolinska Instituudi Bioteaduste Osakond Novumis, Huddinge, Rootsi 1998-2004 : Teadur, KBFI 2004-: Vaneminsener, KBFI
8.	Teaduskraad
9.	Teaduskraadi välja andnud asutus, aasta
10.	Tunnustused
11.	Teadusorganisatsiooniline ja –administratiivne tegevus
12.	Juhendamisel kaitstud väitekirjad
13.	Teadustöö põhisuunad	1.PTCH signaaliülekande rada nahavähi tekkes, 2.CD44 roll tuumori progressioonis
14.	Jooksvad grandid
15.	Teaduspublikatsioonid	P. Kogerman, D. Krause, F. Rahnama, L. Kogerman, A. B. Undén, P. G. Zaphiropoulos, R. Toftgård. (2002) Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein. Oncogene 21:6007-6016 P. Kogerman, T. Grimm, L. Kogerman, D. Krause, R. Toftgård, and P.G. Zaphiropoulos (1999) Mammalian Suppressor of Fused is an inhibitor of GLI1 mediated transcription with ability to modulate GLI1 nuclear-cytoplasmic shuttling. Nature Cell Biology 1:312-318 3. P.G. Smith, R. Garcia and L. Kogerman (1998) Strain increases protein tyrosine phosphorylation in cultured airway smooth muscle cells. Exp. Cell Res. 239:353-360 P.G. Smith, L. Kogerman and L.A. Culp (1996) Mechanical stress increases tyrosine phosphorylation of focal adhesion proteins in cultured airway smooth muscle cells (ASM). Mol. Biol. Cell, 7 (Suppl): 2000 P.G. Smith, R. Garcia and L. Kogerman (1997) Strain increases focal adhesions and cytoskeletal organization in cultured airway smooth muscle cells. Exp. Cell Res. 232:127 5. P.G. Smith, L. Kogerman and R. Moreno (1996) Mechanical strain increased actin filaments and focal adhesions in cultured airway smooth muscle cells. Mol. Biol. Cell, 7 (Suppl): 2264.

viimati muudetud: 29.09.2005

Curriculum Vitae (CV)
1.	First Name	Lembi
2.	Surname	Kogerman
3.	Institution	National Institute of Chemical Physics and Biophysics
4.	Position	senior laboratory assistant
5.	Date of birth	28.04.1966 (day.month.year)
6.	Education	University of Tartu, Biology and Chemistry
7.	Research and professional experience	1987-90: Technician (part-time), Gene Expression Laboratory, University of Tartu 1993 Technician (part-time), United States Biochemical Corporation Custom Sequencing Service , Cleveland, Ohio 1993-97: Research Assistant, Case Western Reserve University, Departments of Molecular Biology and Microbiology and Pediatrics 1997-98: Research Assistant/Graduate Student, Karolinska Institute, Department of Biosciences at Novum, Sweden 1998-2004: Research scientist at NICPB 2004-: Senior Laboratory Assistant, NICPB
8.	Academic degree
9.	Dates and sites of earning the degrees
10.	Honours/awards
11.	Research-administrative experience
12.	Supervised dissertations
13.	Current research program	1. PTCH pathway in skin cancer development 2. Role of CD44 in tumor progression
14.	Current grant funding
15.	List of most important publications	P. Kogerman, D. Krause, F. Rahnama, L. Kogerman, A. B. Undén, P. G. Zaphiropoulos, R. Toftgård. (2002) Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein. Oncogene 21:6007-6016 P. Kogerman, T. Grimm, L. Kogerman, D. Krause, R. Toftgård, and P.G. Zaphiropoulos (1999) Mammalian Suppressor of Fused is an inhibitor of GLI1 mediated transcription with ability to modulate GLI1 nuclear-cytoplasmic shuttling. Nature Cell Biology 1:312-318 3. P.G. Smith, R. Garcia and L. Kogerman (1998) Strain increases protein tyrosine phosphorylation in cultured airway smooth muscle cells. Exp. Cell Res. 239:353-360 P.G. Smith, L. Kogerman and L.A. Culp (1996) Mechanical stress increases tyrosine phosphorylation of focal adhesion proteins in cultured airway smooth muscle cells (ASM). Mol. Biol. Cell, 7 (Suppl): 2000 P.G. Smith, R. Garcia and L. Kogerman (1997) Strain increases focal adhesions and cytoskeletal organization in cultured airway smooth muscle cells. Exp. Cell Res. 232:127 5. P.G. Smith, L. Kogerman and R. Moreno (1996) Mechanical strain increased actin filaments and focal adhesions in cultured airway smooth muscle cells. Mol. Biol. Cell, 7 (Suppl): 2264.

last updated: 29.09.2005