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Elulookirjeldus (CV)
1.Eesnimi Valentina
2.Perekonnanimi Tefanova
3.Töökoht Tervise Arengu Instituut ( TAI )
4.Ametikoht vanemteadur
5.Sünniaeg 27.09.1949 (päev.kuu.aasta)
6.Haridus Leningradi Meditsiiniline Pediaatria Instituut, 1975
7.Teenistuskäik Kliiniline sihtordinatuur laste onkohematoloogia alal, Meditsiiniteaduste Akadeemia Onkoloogiakeskus, Moskva, 1979-1981
Tallinna Epidemioloogia, Mikrobioloogia ja Hügieeni TU Instituut(TEMHTUI), viroloogia osakond, nooremteadur, 1982-1988
Profülaktilise Meditsiini Instituut (PMI, endine TEMHTUI) viroloogia os. vanemteadur, 1988-1997
TAI (endine Eksperimentaalse ja Kliinilise Meditsiini Instituut, EKMI) viroloogia os. vanemteadur, alates 09.1997 k.a.
8.Teaduskraad Meditsiinikandidaat immunoloogias ja allergoloogias ja viroloogias
9.Teaduskraadi välja
andnud asutus, aasta
N.I.Pirogovi nim. Meditsiini Instituut, Moskva, 1987
10.Tunnustused ei
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
PMI-s ja TAI-s(s.h.EKMI-s) töötamise ajal 7 plaanilise teadustöö
läbiviimisel vastutav täitja neljas ja teema juht ühes teadusteemas.
Vastutav täitja neljas ETF grandis( reg.nr.381, 1993, 4218 ja 5961)

Eesti Immunoloogide Seltsi liige, al. 1984-st
Kliinilise Viroloogia Euroopa Seltsi liige, al.1994-st
Eesti Laborimeditsiini Ühingu liige, al.2004-st

PMI viroloogia osakonna stažööri N.Nikiforova diplomitöö teaduslik juhendaja, 1996
12.Juhendamisel kaitstud
väitekirjad
13.Teadustöö põhisuunad Varem- Ägedaid respiratoorseid viirusnakkusi sageli põdevate eelkooliealiste laste immuunstaatuse iseärasused
Al.1994.a-st:B- ja C-viirushepatiitide immunoepidemioloogilised omadused riskirühmades.Immuunsüsteemi erinevad aspektid viirushepatiitide korral
Al. 1999.a-st:Molekulaar-epidemioloogilised uuringud A-,B- ja C-hepatiitide puhul Eestis
14.Jooksvad grandid ETF grant nr.5961: Molekulaar-epidemioloogiline uuring Eestis isoleeritud B-hepatiidiviiruse genotüüpide leviku ja kliinilise tähtsuse väljaselgitamiseks, 2004-2007, vastutav täitja
15.Teaduspublikatsioonid

Adojaan M, Kivisild T, Mannik A, Krispin T, Ustina V, Zilmer K, Liebert E, Jaroslavtsev N, Priimägi L, Tefanova V, Schmidt E, Krohn K, Villems R, Salminen M, Ustav M. Predominance of rare type of HIV-1 in Estonia. J Acquir Immune Defic Syndr. 2005, 39, 5:598-605

Priimägi L, Tefanova V, Tallo T. Emerging viral hepatitis B and C in Estonia. Emerging Biological Threat. NATO Science Series. Series 1. Life and Behavioural Sciences, Ed. by G Berencsi, AS Khan, J Haloužka. IOS Press Amsterdam, Berlin, Oxford, Tokyo, Washington, DC. Published in cooperation with NATO Public Diplomacy Division, 2005, v. 370, 20-25.

Priimägi L, Tefanova, V, Tallo T, Schmidt E. The role of serum Th1 and Th2 cytokines in patients with chronic hepatitis B and C virus infection. Acta Medica Lituanica, 2005, 12, 3:28-31

Tallo T, Norder H, Tefanova V, Krispin T, Priimägi L, Mukomolov S, Mikhailov S, Magnius LO. Hepatitis B virus genotype D strains from Estonia share sequence similarity with strains from Siberia and may specify ayw4. J Med Virol, 2004 Oct; 74(2):221-7.

Tefanova V, Tallo T, Jaroslavtsev N, Kikosh G, Krupskaja L, Lisitsina S, Kutsar K, Priimägi L. B- ja C-viirushepatiidid - aktuaalne epidemioloogiline probleem Eestis viimasel aastakümnel. Eesti Arst, 2004, 83(8):559-562.

Priimägi L, Tefanova V, Tallo T, Schmidt E, Solomonova O, Tuisk T. Th1 and Th2 cytokines in chronic viral hepatitis B and C infection. Voprosy Virusologii, 2003, 48(4):37-40.

Tallo T, Norder H, Tefanova V, Ott K, Prükk T, Solomonova O, Schmidt J, Zilmer L, Priimägi L, Krispin T, Magnius L. Sequental changes in hepatitis A virus genotype distribution in Estonia during 1994 to 2001. J Med Virol 2003, 70(2):187-193.

Tefanova V, Priimägi L, Tallo T, Jaroslavtsev N. Hepatitis B and C infection among intravenous drug users in prisons and visitors of anonymous consulting rooms in Estonia: prevalence and risk factors. Connections, 2003 Nov; 14:8-9.

Priimägi L, Tefanova V, Tallo T, Schmidt E, Solomonova O, Tuisk T, Kikoš G, Krupskaja L, Lisitsyna S. Th1-cytokines in chronic hepatitis B and C. Voprosy Virusologii, 2002, 47(3):23-27.

Tefanova V, Tallo T, Priimägi L, Kikoš G, Krupskaja L, Lisitsyna S, Noorlind J. Hepatitis A in Estonia (1990-1999). Zh Mikrobiol Epidemiol Immunobiol 2002, (2):22-26. 20

Tefanova V, Priimägi L, Tallo T. Functional and metabolic activity of peripheral blood neutrophiles in acute viral hepatitis B and C. Zh Mikrobiol Epidemiol Immunobiol 2001, 1:43-47.

Tallo T, Lappalainen M, Tefanova V, Priimägi L. Distribution of hepatitis C virus genotypes in patients with chronic hepatitis C in Northern Estonia. Acta virologica 2000, 44(3-4):175-178.

Priimägi L, Kremerman I, Tallo T, Tefanova V, Luman M, Osadšaja G. The interferon system in patients maintained by hemodialysis, infected with hepatitis B and C. Voprosy Virusologii, 1999, 44(4):167-169.

Priimägi L, Tefanova V, Tallo T, Osadšaja G. The function of the interferon system in inapparent and clinical hepatitis B and C infection. Voprosy Virusologii, 1999, 44, 2:85-88.

TefanovaV,TalloT,PriimägiL,KikošG,KrupskajaL.EpidemiologicalaspectsofviralhepatitisinEstonia.ZhMikrobiolEpidemiolImmunobiol1999,2:39-42.

viimati muudetud: 13.10.2005

Curriculum Vitae (CV)
1.First Name Valentina
2.Surname Tefanova
3.Institution National Institute for Health Development(NIHD)
4.Position senior researcher
5.Date of birth 27.09.1949 (day.month.year)
6.Education Leningrad´s Pediatric Medical Institute,MD, 1975
7.Research and
professional experience
Tallinn Research Institute of Epidemiology, Microbiology and Hygiene(TRI EMH) Virology Department, junior researcher, 1982-1988
Institute of Preventive Medicine (former TRI EMH), Virology Dept., senior researcher, 1988-1997
NIHD (former Estonian Institute of Experimental and Clinical Medicine), Virology Dept., senior researcher, 1997 till now
8.Academic degree Ph.D., Immunology and Allergology and Virology
9.Dates and sites of
earning the degrees
N.I.Pirogov Medical Institute, Moscow, 1987
10.Honours/awards no
11.Research-administrative
experience
Working at the IPM and NIHD the executor in seven scientific themes and once as the principal investigator.Co-executor in four grants of Estonian Science Foundation

The member of Estonian Society for Immunology, from 1984
The member of European Society for Clinical Virology, from 1994
The member of Estonian Society for Laboratory Medicine, from 2004

Chief of the Diploma N.Nikiforova, probationer, Virology Dept.,IPM,1996
12.Supervised dissertations
13.Current research program Immunoepidemiology of viral hepatitis B and C in groups at increased risk for exposure
Functional state of immune system at the various course of viral hepatitis
Molecular-epidemiological investigations of hepatitis A,B and C viruses in Estonia
14.Current grant funding ESF grant nr.5961: Genotypes of HBV strains isolated in Estonia, their prevalence and clinical relevance: molecular epidemiological study, 2004-2007
15.List of most important publications

Adojaan M, Kivisild T, Mannik A, Krispin T, Ustina V, Zilmer K, Liebert E, Jaroslavtsev N, Priimägi L, Tefanova V, Schmidt E, Krohn K, Villems R, Salminen M, Ustav M. Predominance of rare type of HIV-1 in Estonia. J Acquir Immune Defic Syndr. 2005, 39, 5:598-605

Priimägi L, Tefanova V, Tallo T. Emerging viral hepatitis B and C in Estonia. Emerging Biological Threat. NATO Science Series. Series 1. Life and Behavioural Sciences, Ed. by G Berencsi, AS Khan, J Haloužka. IOS Press Amsterdam, Berlin, Oxford, Tokyo, Washington, DC. Published in cooperation with NATO Public Diplomacy Division, 2005, v. 370, 20-25.

Priimägi L, Tefanova, V, Tallo T, Schmidt E. The role of serum Th1 and Th2 cytokines in patients with chronic hepatitis B and C virus infection. Acta Medica Lituanica, 2005, 12, 3:28-31

Tallo T, Norder H, Tefanova V, Krispin T, Priimägi L, Mukomolov S, Mikhailov S, Magnius LO. Hepatitis B virus genotype D strains from Estonia share sequence similarity with strains from Siberia and may specify ayw4. J Med Virol, 2004 Oct; 74(2):221-7.

Tefanova V, Tallo T, Jaroslavtsev N, Kikosh G, Krupskaja L, Lisitsina S, Kutsar K, Priimägi L. B- ja C-viirushepatiidid - aktuaalne epidemioloogiline probleem Eestis viimasel aastakümnel. Eesti Arst, 2004, 83(8):559-562.

Priimägi L, Tefanova V, Tallo T, Schmidt E, Solomonova O, Tuisk T. Th1 and Th2 cytokines in chronic viral hepatitis B and C infection. Voprosy Virusologii, 2003, 48(4):37-40.

Tallo T, Norder H, Tefanova V, Ott K, Prükk T, Solomonova O, Schmidt J, Zilmer L, Priimägi L, Krispin T, Magnius L. Sequental changes in hepatitis A virus genotype distribution in Estonia during 1994 to 2001. J Med Virol 2003, 70(2):187-193.

Tefanova V, Priimägi L, Tallo T, Jaroslavtsev N. Hepatitis B and C infection among intravenous drug users in prisons and visitors of anonymous consulting rooms in Estonia: prevalence and risk factors. Connections, 2003 Nov; 14:8-9.

Priimägi L, Tefanova V, Tallo T, Schmidt E, Solomonova O, Tuisk T, Kikoš G, Krupskaja L, Lisitsyna S. Th1-cytokines in chronic hepatitis B and C. Voprosy Virusologii, 2002, 47(3):23-27.

Tefanova V, Tallo T, Priimägi L, Kikoš G, Krupskaja L, Lisitsyna S, Noorlind J. Hepatitis A in Estonia (1990-1999). Zh Mikrobiol Epidemiol Immunobiol 2002, (2):22-26. 20

Tefanova V, Priimägi L, Tallo T. Functional and metabolic activity of peripheral blood neutrophiles in acute viral hepatitis B and C. Zh Mikrobiol Epidemiol Immunobiol 2001, 1:43-47.

Tallo T, Lappalainen M, Tefanova V, Priimägi L. Distribution of hepatitis C virus genotypes in patients with chronic hepatitis C in Northern Estonia. Acta virologica 2000, 44(3-4):175-178.

Priimägi L, Kremerman I, Tallo T, Tefanova V, Luman M, Osadšaja G. The interferon system in patients maintained by hemodialysis, infected with hepatitis B and C. Voprosy Virusologii, 1999, 44(4):167-169.

Priimägi L, Tefanova V, Tallo T, Osadšaja G. The function of the interferon system in inapparent and clinical hepatitis B and C infection. Voprosy Virusologii, 1999, 44, 2:85-88.

TefanovaV,TalloT,PriimägiL,KikošG,KrupskajaL.EpidemiologicalaspectsofviralhepatitisinEstonia.ZhMikrobiolEpidemiolImmunobiol1999,2:39-42.

last updated: 13.10.2005

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