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Elulookirjeldus (CV)
1.Eesnimi Katrin
2.Perekonnanimi Aasvee
3.Töökoht Tervise Arengu Instituut
4.Ametikoht Vanemteadur
5.Sünniaeg 09.08.1944 (päev.kuu.aasta)
6.Haridus TÜ Arstiteaduskonna Raviosakond 1962-1968
7.Teenistuskäik 1968-1969 Pärnu Linna Polikliinik, jaoskonnaarst;
1969-1971 TÜ Spordimeditsiini kateedri õpetaja;
1971-1980 TÜ Lihastalitluse hormonaalse regulatsiooni laboratoorium, teadur, alates 1978 vanemteadur;
1981-1987 Eksperimentaalse ja Kliinilise Meditsiini Instituut, vanemteadur;
1987-2004 Eesti Kardioloogia Instituut, vanemteadur;
Alates septembrist 2004 Tervise Arengu Instituudi vanemteadur;
1994-1995 Euroopa Ateroskleroosi Uurimise Grupi II uuring (EARS II), Eesti rühma uurija.
8.Teaduskraad Meditsiiniteaduste kandidaat
9.Teaduskraadi välja
andnud asutus, aasta
Tartu Ülikool, 1978
10.Tunnustused
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
Sihtteemade ja projektide juhtimine:1) II tüüpi diabeediga seotud ateroskleroosi riskitegurite kompleks südamelihase infarkti etioloogias(TÜ alateema) 2003-2007;2) Seosed kroonilise põletiku markerite ja lipoproteiinide parameetrite vahel II tüüpi diabeedi haigetel,ETF grand 2004-2007; 3) Geneetiliselt determineeritud häired lipoproteiinide ainevahetuses varase isheemiatõve tekkes Eestis, 1999- 2002; 4) Ateroskleroosi üldised ja geneetilised riskitegurid Tallinna lastel: kõrge riski strateegia Rahvatervise sihtprogrammi projekt, 1999-2001; 5) Vereseerumi apo A-I ja B sisalduse normväärtused vastsündinutel ja keskealistel, rahvuslik lähenemine, ETF grant, 1996-98; 6) Apo A-I ja B sisalduse võrdlus eestlastel ja soomlastel (rakett-immuunoforeesi metoodika standardiseerimine) ETF grant, 1994-1995; 7) Study on coronary risk factors among schoolchildren of Tallinn. The World Bank & Estonian Health Project 1995.
12.Juhendamisel kaitstud
väitekirjad

Tiiu Roovere, MSc, 2004, juh. Merike Kelve, Katrin Aasvee. Apolipoproteiin E geno- ja fenotüübi võrdlus II tüüpi diabeedi haigetel ja varast müokardiinfarkti põdenutel. Tallinna Tehnikaülikool

13.Teadustöö põhisuunad Ateroskleroosi uued riskitegurid kõrge riski gruppides; varajase ateroskleroosi prognoosimine ja ennetamine; II tüüpi diabeedi kardiovaskulaarsed komplikatsioonid
14.Jooksvad grandid Seosed kroonilise põletiku markerite ja lipoproteiinide parameetrite vahel II tüüpi diabeedi haigetel,ETF grand nr. 5956, 2004-2007
15.Teaduspublikatsioonid

Aasvee K, Jauhiainen M, Kurvinen E, Tur I, Sundvall J, Roovere T, Baburin A.(2006). Determinants of risk factors of atherosclerosis in the postinfarction period: The Tallinn MI Study. Scand J Clin Lab Invest, 66(3):191-199.

Aasvee K, Kurvinen E, Roovere T, Tupits H, Hedman A, Jauhiainen M, Sundvall J.(2005). Cardiovascular risk factors in patients of type 2 diabetes mellitus with and without cardiovascular complications. Atherosclerosis, Suppl. 6(1):152.

Kurvinen E, Aasvee K, Zordania R, Jauhiainen M, Sundvall J.(2005). Serum lipid and apolipoprotein profiles in newborns and 6-year-old children. Tallinn Young Family Study. Scand J Clin Lab Invest, 65(7):541-550.

Aasvee K, Kurvinen E, Jordania R, Jauhiainen M, Sundvall J.(2004). Lipoprotein parameters in relation to other risk factors of atherosclerosis in adults and newborns: Tallinn Young Family Study. Scand J Clin Lab Invest, 64(3):245-254.

Aasvee K, Kurvinen E, Roovere T, Tupits H, Hedman A, Jauhiainen M, Sundvall J. General characteristics of glucose and lipid metabolism in Tallinn Study of coronary risk factors in individuals with type 2 diabetes. Atherosclerosis, 2004; Suppl. 5(4):1.

Kurvinen E, Aasvee K, Zhordania R. Serum lipid and apolipoproteins in newborns and 6-year-old children in relation to apolipoprotein E phenotype. Tallinn Young Family Study. Atherosclerosis, 2004; Suppl. 5(4): 5.

Aasvee K, Kurvinen E, Tur I, Jauhiainen M, Sundvall J. Physical activity and biological risk factors of coronary heart disease: the study of premature myocardial infarction. Papers on Anthropology, 2003; XII,11-20. (ref. SportDiscus, Biosis, EBSCOhost)

Kurvinen E, Aasvee K, Zordania R. Cardiovascular Disease risk factors in preschool children. Papers on Anthropology,2003; XII, pp. 113-123.

Aasvee K, Kurvinen E, Tur I. Obesity as a risk factor for early myocardial infarction in men. Papers on Anthropology XI, 2002; 19-26.

Deakin, S., Leviev, I., Nicaud, V., Meynet, M. C. B., Tiret, L., James, R. W., EARS II group s.h. EKARDI, Saava, M., & Aasvee, K. Paraoxonase-1 L55M polymorphism is associated with an abnormal oral glucose tolerance test and differentiates high risk coronary disease families. Journal of Clinical Endocrinology and Metabolism,2002; 87(3):1268-1273.

Kurvinen E, Aasvee K, Jordania R. Association between birthweight and cardiovascular risk factors in adolescents. Papers on Anthropology XI, 2002; 125-134.

Nicaud, V., Raoux, S., Poirier, O., Cambien, F., O'reilly, D. S., Tiret, L., EARS II group s.h. EKARDI, Saava, M., & Aasvee, K. The TNF alpha/G-308A polymorphism offspring of patients with influences insulin sensitivity in coronary heart disease The European Atherosclerosis Research Study II. Atherosclerosis, 2002; 161(2), 317-325.

Talmud, P. J., Palmen, J., Nicaud, V., Tiret, L., EARS II group s.h. EKARDI, Saava, M., & Aasvee, K. Association of the hormone sensitive lipase -60C > G variant with fasting insulin levels in healthy young men. Nutrition Metabolism and Cardiovascular Diseases, 2002;12(4), 173-177.

Jansen H, Waterworth DM, Nicaud V, Ehnholm C, Talmud PJ. EARS II Group s.h. EKARDI, Saava, M., & Aasvee, K. Interaction of common apolipoprotein C-III (APOC3-482C>T) and hepatic lipase LIPC-514>T) promotor variants affects glucose tolerance in young adults. European Atherosclerosis Research Study II. Ann Human Genetics, 2001; 65 (Pt3):237-43.

Kurvinen E, Aasvee K. Lipoprotein(a) - its physiology and role in cardiovascular diseases risk (review). The Baltic Atherosclerosis Journal (ISSN 1406 – 4871, Riga). 2001(2): 13-17.

Aasvee K, Saava M, Lilienberg K, Tellmann A, Tshaiko L, Sink R. Comparison of schoolchildren with high or low lipid profile. Atherosclerosis, 2000; 151(1): 277.

Tahvanainen E, Molin M, Vainio S, Tiret L, Nicaud V, Farinaro E, Masana L, Ehnholm C. EARS II Group, s.h. EKARDI, Saava, M., & Aasvee, K. Intestinal fatty acid binding protein polymorphism at codon 54 is not associated with postprandial responses to the fat and glucose tolerance tests in healthy young Europeans. Results from EARS II participants. Atherosclerosis, 2000; 152 (2): 317-25 152 (2): 317-25

Aasvee K., Jauhiainen, M., Kurvinen, E., Zordania, R., Sundvall, J., & Ehnholm, C. Lipoprotein(a), Apolipoprotein A-I and B serum levels in young families from Tallinn, Estonia. Relationships with other cardiovascular risk factors and nationality. Scandinavian Journal of Clinical & Laboratory Investigation, 1999; 59(3), 179-189.

Aasvee K, Kurvinen E. Apolipoprotein E polymorphism as a risk factor of coronary hear disease (review). The Baltic Atherosclerosis Journal (ISSN 1406 – 4871, Tallinn, Riia, Vilnius), 1999; (1): 7-11.

Dallongeville J, Tiret L, Visvikis S, O’Reilly D,St.J, Saava M, Tsitouris G, Rosseneu M, DeBacker G, Humpries SE, Beisiegel U, EARS II group s.h. EKARDI, Saava, M., & Aasvee, K. Effect of apoE phenotype on plasma postprandial triglycerides levels in young male adults with and without a familiar history of myocardial infarction: the EARS II study. Atherosclerosis, 1999; 145: 381-388.

Kurvinen, E., Zordania, R., & Aasvee, K. Cardiovascular Risk Factors in Young Families. Relation to the Course of Pregnancy and the State of Health of the Newborn. Kardiologiya, 1999; 39(10), 52-56.

Aasvee K, Kurvinen E, Jordania R. Effect of dietary pattern on serum lipoprotein parameters in young families.Atherosclerosis 1997; 134(1-2):152.

Saava M, Aasvee K, Tchaiko L. Atherosclerosis risk factors and nutrition of male students with the paternal premature myocardial infarction. Atherosclerosis 1997; 134(1-2):169

6. Tellman AK, Saava ME, Aasvee KE. Effects of prophylactic vitamin administration to Tallin's schoolchildren on their health and physical development. (Russian). Vopr Pitan 1992; (3):36-40.

Seene TP, Alev KP, Tomson KE (praegu Aasvee K), Viru AA. (1982)[Adaptation of skeletal muscle and myocardium to increased motor activity in hypo- and athyroid rats]Russian. Vopr Med Khim;28(2):20-24.

Seene TP, Alev KP, Tomson KE (praegu Aasvee K), Viru AA. (1981) [Role of the thyroid gland in skeletal muscle adaptation to increased motor activity]Russian. Fiziol Zh SSSR Im I M Sechenova;67(2):299-305.

Viru AA, Smirnova TA, Seene TP, Tomson KE (praegu Aasvee KE), Eller AK.(1979). [Participation of glucocorticoids in development and provisions for work capacity]Russian. Fiziol Zh SSSR Im I M Sechenova. 65(12):1790-1795.

Tomson KE (praegu Aasvee K), Kallikorm AP.(1974)[Effect of physical load on the content of protein-bound iodine in the blood plasma of trained and untrained rats]Russian.Probl Endokrinol ;20(5):58-61.

viimati muudetud: 04.10.2005

Curriculum Vitae (CV)
1.First Name Katrin
2.Surname Aasvee
3.Institution National Institute for Health Development
4.Position Senior Researcher
5.Date of birth 09.08.1944 (day.month.year)
6.Education 1962-1968 Medical Faculty of Tartu University
7.Research and
professional experience
1968-69 Physician in the Policlinic of the Hospital of Pärnu;
1969-71 Tartu University, tutor of Chair of Sport Medicine;
1971-80 Tartu University, researcher/ Sen.researcher, of the Laboratory of Hormonal Regulation of Physical Activity;
1981-87 Institute of Experimental & Clinical Medicine,Sen.researcher
1987-2004 Estonian Institute of Cardiology, Senior researcher;
Since 2004 National Institute for Health Development, Senior Researcher;
1994-95 Researcher in European Atherosclerosis Study Group (EARS II).
8.Academic degree PhD
9.Dates and sites of
earning the degrees
Tartu University, Faculty of Medicine, 1978
10.Honours/awards
11.Research-administrative
experience
Leader of target financed and grant projects: 1)Cluster of risk factors of atherosclerosis in type II diabetes mellitus in aetiology of myocardial infarction, 2003-2007; 2) Associations between markers of chronic inflammation and lipoprotein parameters in patients of type II Diabetes Mellitus, ESF grant 2004-2007; 3)Genetically determined variation in blood lipoproteins and premature coronary artery disease in Estonia, 1999-2002; 4) General and genetic risk factors of atherosclerosis in children of Tallinn: The high risk strategy, 1999-2001; 5) Comparison of serum ApoA-I and B levels in Estonians and Finns (standardization of rocket-immuno-electrophoresis for determination of apoA-I and B.ESF grant,1994-1995. 6)Serum apoA-I and B in newborns and middle-aged population. ESF grant, 1996-1998. 7) Grant of International Bank of Reconstruction and Development: Study on coronary risk factors among schoolchildren of Tallinn, 1995.
12.Supervised dissertations

Tiiu Roovere, MSc, 2004, superv. Merike Kelve, Katrin Aasvee. Apolipoproteiin E geno- ja fenotüübi võrdlus II tüüpi diabeedi haigetel ja varast müokardiinfarkti põdenutel. Tallinna Tehnikaülikool

13.Current research program Emerging risk factors of atherosclerosis in high-risk groups; prognostic markers and prevention of premature atherosclerosis; Cardiovascular complications of the type 2 Diabetes Mellitus
14.Current grant funding Associations between markers of chronic inflammation and lipoprotein parameters in patients of type II Diabetes Mellitus, grant of Estonian Science Foundation nr. 5956; 2004-2007
15.List of most important publications

Aasvee K, Jauhiainen M, Kurvinen E, Tur I, Sundvall J, Roovere T, Baburin A.(2006). Determinants of risk factors of atherosclerosis in the postinfarction period: The Tallinn MI Study. Scand J Clin Lab Invest, 66(3):191-199.

Aasvee K, Kurvinen E, Roovere T, Tupits H, Hedman A, Jauhiainen M, Sundvall J.(2005). Cardiovascular risk factors in patients of type 2 diabetes mellitus with and without cardiovascular complications. Atherosclerosis, Suppl. 6(1):152.

Kurvinen E, Aasvee K, Zordania R, Jauhiainen M, Sundvall J.(2005). Serum lipid and apolipoprotein profiles in newborns and 6-year-old children. Tallinn Young Family Study. Scand J Clin Lab Invest, 65(7):541-550.

Aasvee K, Kurvinen E, Jordania R, Jauhiainen M, Sundvall J.(2004). Lipoprotein parameters in relation to other risk factors of atherosclerosis in adults and newborns: Tallinn Young Family Study. Scand J Clin Lab Invest, 64(3):245-254.

Aasvee K, Kurvinen E, Roovere T, Tupits H, Hedman A, Jauhiainen M, Sundvall J. General characteristics of glucose and lipid metabolism in Tallinn Study of coronary risk factors in individuals with type 2 diabetes. Atherosclerosis, 2004; Suppl. 5(4):1.

Kurvinen E, Aasvee K, Zhordania R. Serum lipid and apolipoproteins in newborns and 6-year-old children in relation to apolipoprotein E phenotype. Tallinn Young Family Study. Atherosclerosis, 2004; Suppl. 5(4): 5.

Aasvee K, Kurvinen E, Tur I, Jauhiainen M, Sundvall J. Physical activity and biological risk factors of coronary heart disease: the study of premature myocardial infarction. Papers on Anthropology, 2003; XII,11-20. (ref. SportDiscus, Biosis, EBSCOhost)

Kurvinen E, Aasvee K, Zordania R. Cardiovascular Disease risk factors in preschool children. Papers on Anthropology,2003; XII, pp. 113-123.

Aasvee K, Kurvinen E, Tur I. Obesity as a risk factor for early myocardial infarction in men. Papers on Anthropology XI, 2002; 19-26.

Deakin, S., Leviev, I., Nicaud, V., Meynet, M. C. B., Tiret, L., James, R. W., EARS II group s.h. EKARDI, Saava, M., & Aasvee, K. Paraoxonase-1 L55M polymorphism is associated with an abnormal oral glucose tolerance test and differentiates high risk coronary disease families. Journal of Clinical Endocrinology and Metabolism,2002; 87(3):1268-1273.

Kurvinen E, Aasvee K, Jordania R. Association between birthweight and cardiovascular risk factors in adolescents. Papers on Anthropology XI, 2002; 125-134.

Nicaud, V., Raoux, S., Poirier, O., Cambien, F., O'reilly, D. S., Tiret, L., EARS II group s.h. EKARDI, Saava, M., & Aasvee, K. The TNF alpha/G-308A polymorphism offspring of patients with influences insulin sensitivity in coronary heart disease The European Atherosclerosis Research Study II. Atherosclerosis, 2002; 161(2), 317-325.

Talmud, P. J., Palmen, J., Nicaud, V., Tiret, L., EARS II group s.h. EKARDI, Saava, M., & Aasvee, K. Association of the hormone sensitive lipase -60C > G variant with fasting insulin levels in healthy young men. Nutrition Metabolism and Cardiovascular Diseases, 2002;12(4), 173-177.

Jansen H, Waterworth DM, Nicaud V, Ehnholm C, Talmud PJ. EARS II Group s.h. EKARDI, Saava, M., & Aasvee, K. Interaction of common apolipoprotein C-III (APOC3-482C>T) and hepatic lipase LIPC-514>T) promotor variants affects glucose tolerance in young adults. European Atherosclerosis Research Study II. Ann Human Genetics, 2001; 65 (Pt3):237-43.

Kurvinen E, Aasvee K. Lipoprotein(a) - its physiology and role in cardiovascular diseases risk (review). The Baltic Atherosclerosis Journal (ISSN 1406 – 4871, Riga). 2001(2): 13-17.

Aasvee K, Saava M, Lilienberg K, Tellmann A, Tshaiko L, Sink R. Comparison of schoolchildren with high or low lipid profile. Atherosclerosis, 2000; 151(1): 277.

Tahvanainen E, Molin M, Vainio S, Tiret L, Nicaud V, Farinaro E, Masana L, Ehnholm C. EARS II Group, s.h. EKARDI, Saava, M., & Aasvee, K. Intestinal fatty acid binding protein polymorphism at codon 54 is not associated with postprandial responses to the fat and glucose tolerance tests in healthy young Europeans. Results from EARS II participants. Atherosclerosis, 2000; 152 (2): 317-25 152 (2): 317-25

Aasvee K., Jauhiainen, M., Kurvinen, E., Zordania, R., Sundvall, J., & Ehnholm, C. Lipoprotein(a), Apolipoprotein A-I and B serum levels in young families from Tallinn, Estonia. Relationships with other cardiovascular risk factors and nationality. Scandinavian Journal of Clinical & Laboratory Investigation, 1999; 59(3), 179-189.

Aasvee K, Kurvinen E. Apolipoprotein E polymorphism as a risk factor of coronary hear disease (review). The Baltic Atherosclerosis Journal (ISSN 1406 – 4871, Tallinn, Riia, Vilnius), 1999; (1): 7-11.

Dallongeville J, Tiret L, Visvikis S, O’Reilly D,St.J, Saava M, Tsitouris G, Rosseneu M, DeBacker G, Humpries SE, Beisiegel U, EARS II group s.h. EKARDI, Saava, M., & Aasvee, K. Effect of apoE phenotype on plasma postprandial triglycerides levels in young male adults with and without a familiar history of myocardial infarction: the EARS II study. Atherosclerosis, 1999; 145: 381-388.

Kurvinen, E., Zordania, R., & Aasvee, K. Cardiovascular Risk Factors in Young Families. Relation to the Course of Pregnancy and the State of Health of the Newborn. Kardiologiya, 1999; 39(10), 52-56.

Aasvee K, Kurvinen E, Jordania R. Effect of dietary pattern on serum lipoprotein parameters in young families.Atherosclerosis 1997; 134(1-2):152.

Saava M, Aasvee K, Tchaiko L. Atherosclerosis risk factors and nutrition of male students with the paternal premature myocardial infarction. Atherosclerosis 1997; 134(1-2):169

6. Tellman AK, Saava ME, Aasvee KE. Effects of prophylactic vitamin administration to Tallin's schoolchildren on their health and physical development. (Russian). Vopr Pitan 1992; (3):36-40.

Seene TP, Alev KP, Tomson KE (praegu Aasvee K), Viru AA. (1982)[Adaptation of skeletal muscle and myocardium to increased motor activity in hypo- and athyroid rats]Russian. Vopr Med Khim;28(2):20-24.

Seene TP, Alev KP, Tomson KE (praegu Aasvee K), Viru AA. (1981) [Role of the thyroid gland in skeletal muscle adaptation to increased motor activity]Russian. Fiziol Zh SSSR Im I M Sechenova;67(2):299-305.

Viru AA, Smirnova TA, Seene TP, Tomson KE (praegu Aasvee KE), Eller AK.(1979). [Participation of glucocorticoids in development and provisions for work capacity]Russian. Fiziol Zh SSSR Im I M Sechenova. 65(12):1790-1795.

Tomson KE (praegu Aasvee K), Kallikorm AP.(1974)[Effect of physical load on the content of protein-bound iodine in the blood plasma of trained and untrained rats]Russian.Probl Endokrinol ;20(5):58-61.

last updated: 04.10.2005

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