[ sulge aken ]

Elulookirjeldus (CV)
1.Eesnimi Erkki
2.Perekonnanimi Truve
3.Töökoht Tallinna Tehnikaülikool, geenitehnoloogia instituut
4.Ametikoht direktor
5.Sünniaeg 23.02.1965 (päev.kuu.aasta)
6.Haridus Tallinna 21. Keskkool - 1983
Tartu Ülikool, Bioloogia-geograafiateaduskond, cum laude geneetikuna - 1988
7.Teenistuskäik 1988 TA Keemilise ja Bioloogilise Füüsika Instituut (KBFI), vaneminsener
1988 - 1991 TA KBFI aspirant
1991 - 1996 KBFI nooremteadur
1996 KBFI teadur
1996 – praeguseni KBFI vanemteadur
1997 – 1998 Tallinna Pedagoogikaülikool, dotsent (1/4)
1997 – praeguseni Tallinna Tehnikaülikool (TTÜ), geenitehnoloogia instituudi direktor, geenitehnoloogia professor
8.Teaduskraad PhD
9.Teaduskraadi välja
andnud asutus, aasta
Tartu Ülikool, 1996
10.Tunnustused 1985 - Üliõpilaste Teaduslik Ühing, auhind
1996 - Academia Europae, award for young Baltic scholars
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
Nõukogu esimees:

EV Keskkonnaministeeriumi geenitehnoloogia komisjon
TTÜ Matemaatika-loodusteaduskonna geenitehnoloogia instituut
AS Vähiuuringute Tehnoloogia Arenduskeskus

Nõukogu liige:

Euroopa Taimeteaduse Organisatsioon (EPSO)
Jõgeva Sordiaretuse Instituut
Tervise Arengu Instituut
EV Põllumajandusministeeriumi põllumajandusteaduste nõukogu
EV Põllumajandusministeeriumi uuendtoidu komisjon
TTÜ Matemaatika-loodusteaduskond
TTÜ biomeditsiinitehnika keskus
Artur Linnu Stipendiumifond
AS Quattromed
SA Eesti Geenikeskus.

Konverentside korraldamine:

“The problems of plant virology in the Baltic Sea region”. 21.-23.03.01. Kaunas.
1st Nordic Plant Virology Meeting. 26.-29.06.01. Punkaharju.
3rd EPSO Conference “Plant Dynamics: from Molecules to Ecosystems”. 2805-01.06.06. Visegrad.

Kursuste korraldamine:

Rahvusvahelised praktilised kursused “Techniques in plant molecular biology.” Tallinn, 4.-8.12.95.

Osalemine kaitsmiskomisjonides:
kaks korda TTÜ PhD kaitsmiskomisjoni esimees
kaks korda TTÜ PhD kaitsmiskomisjoni liige
üks kord Rootsi Põllumajandusülikooli PhD kaitsmiskomisjoni liige
korduvalt TTÜ geenitehnoloogia instituudi ning EPMÜ Eksperimentaalbioloogia Instituudi MSc kaitsmiskomisjoni esimees

1997-2000 - Euroopa Komisjoni INCO-Copernicus projekti ERBIC15CT-96-0907 teaduslik koordinaator,.
1997-2005 Keemilise ja Bioloogilise Füüsika Instituudi nõukogu liige
1999 - bioloogilise mitmekesisuse säilitamise Eesti riikliku strateegia ja tegevuskava biotehnoloogia töögrupi liige
1999 - Eesti uuendtoidu alase seadusandluse väljatöötamise teaduslik ekspert
1999-2000 - Eesti Geenivaramu projekti väljatöötamise nõukogu liige
2001 - II rahvusliku aruande koostamise bioloogilise mitmekesisuse konventsiooni täitmise kohta Eestis töögrupi liige
2001 - Eesti Vabariigi esindaja ÜRO ekspertide kohtumisel “Capacity building for the Cartagena protocol on biosafety”
2001-2002 - TTÜ Matemaatika-loodusteaduskonna loomise projektijuht
2001-2006 - TTÜ teaduse tippkeskuse ”Keemiline bioloogia” juht
2002-2003 - Cartagena bioloogilise ohutuse protokolli ellurakendamise Eesti programmi juhtkomitee liige.
2002-2003 - EV Majandusministeeriumi biotehnoloogia ekspertgrupi liige
2002-2003 - rahvuslik esindaja European Research Area pilootprojektis Plant Genomics
2002-2004 - Helsinki-Tallinn Science Twin-City töörühma liige
2002-2005 - Euroopa Komisjoni 5. raamprogrammi projekti QLG2-2002-01673 koordinaator
2002-2007 - rahvuslik ekspert Euroopa Komisjoni 6. Raamprogrammi 1. valdkonnas “Life Sciences, Genomics and Biotechnology for Health”
2003-2005 - TTÜ nõukogu liige
2003-2007 - BioSpinno projekti juhtkomitee liige
2004 - Eesti Vabariigi esindaja Cartagena protokolli osapoolte 1. kohtumisel
2004 - Foundation for Public Research and Regulation asutajaliige
2004-2005 - Põllumajandusministeeriumi nõuandva komisjoni ”Geneetiliselt muundatud ja mittemuundatud põllumajanduskultuuride kooseksisteerimise alase strateegia ning seadusandluse väljatöötamiseks” liige
2004-2005 - TTÜ teadus- ja arendustegevuse strateegia väljatöötamise töörühma liige
2005-2008 - Biomeditsiini ja biotehnoloogia doktorikooli juhtkomitee liige
2005-2008 - TTÜ keemia, biotehnoloogia ja biomeditsiini valdkonna infrastruktuuri arendamise projektijuht

Korduvalt olen osalenud Euroopa Komisjoni 4., 5. ja 6. raamprogrammi projektide evalvatsioonil eksperdina, olen hinnanud INTAS-i, Eesti Teadusfondi ning Eesti Tehnoloogiaagentuuri projektitaotlusi ja aruandeid. Olen osalenud Fulbrighti programmi taotluste hindamisel.
Olen hinnanud anonüümse referiina ajakirjadesse Journal of Virology, Virology, Nucleic Acids Research, Plant Molecular Biology, Transgenic Research, Molecular Breeding saadetud käsikirju.
12.Juhendamisel kaitstud
väitekirjad

Birger Ilau, MSc, 2005, juh. Erkki Truve, Eve-Ly Ojangu, Heiti Paves. Arabidopsis thaliana müosiinide ATM1 ja MYA1 promootorite poolt suunatud GUS reportergeeni ekspressioon transgeensetes taimedes. Tallinna Tehnikaülikool

Kristel Järve, MSc, 2005, juh. Erkki Truve, Eve-Ly Ojangu, Heiti Paves. Arabidopsis thaliana müosiin XIK on vajalik juurekarvade normaalseks arenguks. Tallinna Tehnikaülikool

Allan Olspert, MSc, 2004, juh. Erkki Truve. The role of the arginine-rich region of cocksfoot mottle virus coat protein in virus movement. Tallinna Tehnikaülikool

Silva Sütt, MSc, 2004, juh. Erkki Truve, Merike Meier. The RNA-binding properties of cocksfoot mottle sobemovirus polyprotein. Tallinna Tehnikaülikool

Marju Buschmann, MSc, 2003, juh. Erkki Truve, Lenne Nigul. RNaas L-i inhibiitori geenile sarnaste avatud lugemisraamide uuriminhe müürloogas. Tallinna Tehnikaülikool

Anu Tiidema, MSc, 2001, juh. Erkki Truve, Kadri Järve. Taimede regeneratsioon ja geneetiline transformatsioon mõnedel kohalikel rukki- ja odrasortidel. Eesti Põllumajandusülikool

Tiina Tamm, PhD, 2000, juh. Erkki Truve. Cocksfoot mottle virus: the genome organisation and translational strategies. Tartu Ülikool

Kadri Tomasson, MSc, 1999, juh. Erkki Truve. Kartulimugulaviroidi (PSTV) replikatsioon ja lokalisatsioon tomatis. Tartu Ülikool

Merike Meier, MSc, 1999, juh. Erkki Truve, Tiina Tamm. Expression of cocksfoot mottle virus proteins in insect cells. Tallina Tehnikaülikool

Marie-Lise Bouscaren, MSc, 1996, juh. Erkki Truve. The importance of potato virus X coat protein in virus resistance and symptom development. Tartu Ülikool

Tiina Tamm, MSc, 1994, juh. Erkki Truve. Characterization of cocksfoot mottle virus. Tartu Ülikool

13.Teadustöö põhisuunad Keraheina laiguviiruse molekulaarne iseloomustamine, taimeviiruste vektorid.
RNA vaigistamine ja selle supressioon taimedes.
Mikrofilamentide süsteemi valkude iseloomustamine taimedes.
Nisu resistentsusgeenid.
14.Jooksvad grandid 2003-2007. Sihtfinantseeritav teema “Taimede ja taimeviiruste geenide ekspressiooni ja funktsiooni uurimine”.
2004-2007. Eesti Teadusfond, #5909. “Keskkonnaohutute taimsete viirusvektorite konstrueerimine.”
2004-2007. Eesti Teadusfond, #5939. “Post-transkriptsiooniline geenivaigistamine ja selle supressorid.”
2002-2005. The European Commission 5. Framework RTD project QLG2-2002-01673 “Virus-Induced gene Silencing: unravelling the basis of a mechanism and its exploitation for the analysis of a multitude of individual gene functions in plants” (koordinaator).
2005-2007 The European Commission 6. Framework coordination action FOOD-CT-2004-514048 “Coordination and research on genetic resistance to plant pathogenic viruses, and their vectors, in European crops”
2004-2007 Eesti Põllumajandusministeerium. “Molekulaarsete ja koekultuurimeetodite rakendamine sordiaretuses ja taimse materjali analüüsis”.
15.Teaduspublikatsioonid

Meier, M., Paves, H., Olspert, A., Tamm, T., Truve, E. 2005. P1 protein of Cocksfoot mottle virus is indispensable for the systemic spread of the virus. Virus Genes, in press.

Nigul, L., Olspert, A., Meier, M., Paves, H., Talpsep, T., Truve, E. 2004. New plant vectors for protein tagging with E2 epitope. Plant Mol. Biol. Rep. 22:399-407.

Paves, H., Truve, E. 2004. Incorporation of mammalian actin into microfilaments in plant cell nucleus. BMC Plant Biol. 4:7.

Tiidema, A., Truve, E. 2004. Efficient regeneration of fertile barley plants from callus cultures of several Nordic cultivars. Hereditas 140:171-176.

Truve, E. Genus: Sobemovirus. 2004. In: Viruses and Virus Diseases of Poaceae (Gramienae). Lapierre H., Signoret P.-A., eds. INRA Editions.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 2001. Reconstitution of multiple virus resistance in transgenic plants. GR patent 3035873.

Mäkinen, K., Mäkeläinen, K., Arshava, N., Tamm, T., Merits, A., Truve, E., Zavriev, S., Saarma, M. 2000. Characterisation of VPg and the polyprotein processing of Cocksfoot mottle virus (genus Sobemovirus). J. gen. Virol. 81:2783-2789.

Sarmiento, C., Hunt, R., Merits, A., Paves, H., Järvekülg, L., Truve, E. 2000. Subcellular localization of five potato A potyvirus proteins. In: Proc. of the 5th Congress of the European Foundation for Plant Pathology. Taormina – Giardini Naxos. p. 300-303.

Tamm, T., Truve, E. 2000. RNA-binding activities of cocksfoot mottle sobemovirus proteins. Virus Res. 66:197-207.

Tamm, T., Truve, E. 2000. Sobemoviruses. J. Virol. 74:6231-6241.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 1999. Reconstitution of multiple virus resistance in transgenic plants. European patent 632835.

Tamm, T., Mäkinen, K., Truve, E. 1999. Identification of genes encoding for the cocksfoot mottle virus proteins. Arch. Virol. 144: 1557-1567.

Pata, I., Truve, E. 1998. Gel electrophoresis, transfer and hybridization of nucleic acids. In: Gene Manipulation Techniques. (Berzinš, V., Ed.). Springer Verlag, Berlin. 104-134.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 1998. Reconstitution of multiple virus resistance in transgenic plants. RU patent 2125606.

Tamm, T., Truve, E. 1998. Protein synthesis in cell-free systems. In: Gene Manipulation Techniques. (Berzinš, V., Ed.). Springer Verlag, Berlin. 145-163.

Tamm, T., Truve, E., Mäkinen, K., Saarma, M. 1997. Expression of cocksfoot mottle virus proteins in bacterial and plant cells. FASEB J. 11: A1402.

Tomasson, K., Virumäe, K., Truve, E. 1997. On Agrobacterium-mediated genetic transformation of barley. FASEB J. 11: A1102.

Truve, E., Næss, V., Blystad, D. R., Järvekülg, L., Mäkinen, K., Tamm, T., Munthe, T. 1997. Detection of cocksfoot mottle virus particles and RNA in oat plants by immunological, biotechnical and electronmicroscopical techniques. Arch. Phytopath. Pflanz. 30: 473-485.

Saarma, M., Kelve, M., Truve, E., Teeri, T. H. 1996. Transgenic plants displaying multiple virus resistance and a process for their production. US Patent No. 5,589,625.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 1996. Reconstitution of multiple virus resistance in transgenic plants. AU patent 669130.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 1996. Reconstitution of multiple virus resistance in transgenic plants. PL patent 171446.

Truve, E., Nigul, L., Teeri, T. H., Kelve, M. 1996. The effects of 2-5A on protein synthesis in wheat germ extracts and tobacco protoplasts. Nucleos. Nucleot. 15: 1097-1111.

Kuusksalu, A., Truve, E., Aaspõllu, A., Kelve, M., Scheffer, U., Müller, W. E. G. 1995. Impairment of intracellular antiviral defence with age: age-dependent changes in expression of interferon-induced and double-stranded RNA-activated 2-5A synthetase in rat. Mech. Ageing Dev. 78: 103-115.

Mäkinen, K., Næss, V., Tamm. T., Truve, E., Aaspõllu, A., Saarma, M. 1995. The putative replicase of the cocksfoot mottle sobemovirus is translated as a part of the polyprotein by -1 ribosomal frameshift. Virology 207: 566-571.

Mäkinen, K., Tamm, T., Næss, V., Truve, E., Puurand, Ü., Munthe, T., Saarma, M. 1995. Characterization of cocksfoot mottle sobemovirus genomic RNA and its sequence comparison with related viruses. J. gen. Virol. 76: 1817-1825.

Truve, E., Järvekülg, L., Bouscaren, M.-L., Aaspõllu, A., Priimägi, A., Saarma, M. 1995. Different propagation levels of potato virus X (PVX) isolates in PVX coat protein expressing tobacco plants and protoplasts do not correlate with coat protein sequence similarities. Arch. Phytopath. Pflanz. 30: 15-30.

Kelve, M., Truve, E., Aaspõllu, A., Kuusksalu, A., Dapper, J., Perovic, S., Müller, W. E. G. 1994. Reduction of 2’-5’-oligoadenylate synthetase mRNA level in rat pheochromocytoma PC12 cells during apoptosis. In: Use of Aquatic Invertebrates as Tools for Monitoring of Environmental Hazards. (Müller, W. E. G., Ed.). Gustav Fisher Verlag, Stuttgart. 97-108.

Kelve, M., Truve, E., Aaspõllu, A., Kuusksalu, A., Dapper, J., Perovic, S., Müller, W. E. G., Schröder, H. C. 1994. Rapid reduction of mRNA coding for 2'-5'-oligoadenylate synthetase in rat pheochromocytoma PC12 cells during apoptosis. Cell. mol. Biol. 40: 165-173.

Saarma, M., Truve, E., Seppänen, P. 1994. Transgenic plants transformed with murine 2-5A synthetase gene are protected to several RNA viruses. Univ. Helsinki Dep. Plant Prod. Publ. 43: 11-12.

Truve, E., Kelve, M., Aaspõllu, A., Kuusksalu, A., Seppänen, P., Saarma, M. 1994. Principles and background for the construction of transgenic plants displaying multiple virus resistance. Arch. Virol. S9: 41-50.

Truve, E., Kelve, M., Aaspõllu, A., Schröder, H. C., Müller, W. E. G. 1994. Homologies between different forms of 2-5A synthetase. Progr. Mol. Subcell. Biol. 14: 139-149.

Truve, E., Aaspõllu, A., Honkanen, J., Puska, R., Mehto, M., Hassi, A., Teeri, T. H., Kelve, M., Seppänen, P., Saarma, M. 1993. Transgenic potato plants expressing mammalian 2'-5' oligoadenylate synthetase are protected from potato virus X infection under the field conditions. Bio/Technology 11: 1048-1052.

Saichenko, T. A., Sherbatenko, I. S., Truve, E., Kanevsky, I. F., Gleba, Yu. Yu. 1992. Resistance to transgenic tobacco plants expressing gene of (2'-5') oligoadenylate synthetase in mouse tobacco mosaic virus. Dokl. Akad. Nauk Ukr., No. 9, 145-148.

Kelve, M., Truve E., Priimägi, A., Järvekülg, L., Saarma, M. 1991. Studies on virus resistance in plants. In: UNESCO Regional Office for Science and Technology for Europe. Technical Report No. 6: International Symposium "Virology, Immunology and Society". ROSTE, Venice. 273-285.

viimati muudetud: 06.10.2005

Curriculum Vitae (CV)
1.First Name Erkki
2.Surname Truve
3.Institution Tallinn University of Technology, Department of Gene Technology
4.Position director
5.Date of birth 23.02.1965 (day.month.year)
6.Education Tallinn Secondary School No. 21 - 1983
Tartu University, Faculty of Biology and Geography, cum laude as geneticist – 1988
7.Research and
professional experience
1988 – National Institute of Chemical Physics and Biophysics (NICPB), Tallinn, senior engineer
1988-1991 - NICPB, PhD student
1991-1996 - NICPB, junior research scientist
1996 - NICPB, research scientist
1996 till now - NICPB, senior research scientist
1996-1997 - Tallinn Pedagogical University, principal lecturer in cell biology
1997 till now - Tallinn University of Technology, Department of Gene Technology, director, professor in gene technology
8.Academic degree PhD
9.Dates and sites of
earning the degrees
Tartu University, 1996
10.Honours/awards 1985 - Estonian Students Scientific Society, award
1996 - Academia Europae, award for young Baltic scholars
11.Research-administrative
experience
Head of the board or council:

Estonian Gene Technology Committee
Department of Gene Technology at TUT
Competence Centre for Cancer Research Ltd., Tallinn

Member of the board or council:

European Plant Science Foundation
Jõgeva Plant Breeding Institute
National Institute of Health Development, Tallinn
Council of agricultural sciences at the Estonian Ministry of Agriculture
Estonian Novel Food Committee
Faculty of Science at TUT
Centre for Biomedical Engineering at TUT
A. Lind Stipend Fund
Quattromed Ltd, Tartu
Estonian Genome Centre Foundation

Organization of conferences:

Baltic/Nordic Workshop “The problems of plant virology in the Baltic Sea region”, Kaunas. 2001.
1st Nordic Plant Virology Meeting, Punkaharju. 2001.
3rd EPSO Conference “Plant Dynamics: from Molecules to Ecosystems”. 2805-01.06.06. Visegrad.

Organization of courses:
In collaboration with Wye College, Univ. of London the practical course for Baltic students “Techniques in plant molecular biology”, Tallinn. 1995.

Head of PhD thesis evaluation committee in two occasions at TUT
Member of PhD thesis evaluation committee in two occasions at TUT
Member of PhD thesis evaluation committee in one occasion at Swedish University of Agricultural Sciences
Head of MSc thesis evaluation committee in several occasions at TUT and Estonian Agricultural University

1997-2000 - Scientific coordinator of the EC INCO-Copernicus project ERBIC15CT-96-0907
1997-2005 - National Institute of Chemical Physics and Biophysics, member of the scientific board
1999 - Member of the executive committee for biotechnology at the national strategic and action programme of biodiversity
1999 – Scientific expert for the development of the novel food regulations in Estonia
1999-2000 – member of the council of the Estonian Genome Project
2001 – Representative of the Republic of Estonia at UNEP Open-ended Meeting of Experts on Capacity-Building for the Implementation of the Biosafety Protocol
2001 - Member of the executive committee for second national report to the Convention on Biological Diversity
2001-2002 – project leader for the foundation of the Faculty of Science at Tallinn Univ. of Technology
2001-2006 – head of the Centre of Excellence “Chemical Biology” at Tallinn Univ. of Technology
2002-2003 – Member of the national coordinating committee for the UN programme “Development of National Biosafety Frameworks”
2002-2003 – Member of the Estonian Biotechnology Expert Group at the Ministry of Economic Affairs
2002-2003 - National representative at the European Research Area pilot project in Plant Genomics
2002-2004 – Helsinki-Tallinn Science Twin-City Project. Member of the steering committee
2002-2005 – coordinator of the EC 5th Framework Programme RTD project QLRT-2001-01673 “Virus-Induced gene Silencing: unravelling the basis of a mechanism and its exploitation for the analysis of a multitude of individual gene functions in plants”
2002-2007 - National expert of the EC 6th Framework Programme Priority Area 1 “Life Sciences, Genomics and Biotechnology for Health”
2003-2007 - Member of the executive committee for the BioSpinno project
2003-2005 – member of the board of Tallinn University of Technology
2004 - Representative of the Republic of Estonia at the First Meeting of the Parties to the Cartagena Protocol on Biosafety.
2004 - Foundation for Public Research and Regulation, founding member
2004-2005 – member of the expert group for the R&D strategy of Tallinn Univ. of Technology
2004-2005 – member of the expert group at the Ministry of Agriculture on co-existence of GM and non-GM crops
2005-2008 - member of the executive committee for the Graduate School of Biotechnology and Biomedicine
2005-2008 - head of the infrastructure development program for the field of chemistry, biotechnology and biomedicine at TUT

Referee for journals Journal of Virology, Virology, Nucleic Acids Research, Plant Molecular Biology, Transgenic Research, Molecular Breeding.
Reviewer and evaluator in many instances the 4., 5., and 6. Framework programme of the European Commission, for INTAS, Estonian Science Foundation, Enterprise Estonia and the Fulbright program.
12.Supervised dissertations

Birger Ilau, MSc, 2005, superv. Erkki Truve, Eve-Ly Ojangu, Heiti Paves. Arabidopsis thaliana müosiinide ATM1 ja MYA1 promootorite poolt suunatud GUS reportergeeni ekspressioon transgeensetes taimedes. Tallinna Tehnikaülikool

Kristel Järve, MSc, 2005, superv. Erkki Truve, Eve-Ly Ojangu, Heiti Paves. Arabidopsis thaliana müosiin XIK on vajalik juurekarvade normaalseks arenguks. Tallinna Tehnikaülikool

Allan Olspert, MSc, 2004, superv. Erkki Truve. The role of the arginine-rich region of cocksfoot mottle virus coat protein in virus movement. Tallinna Tehnikaülikool

Silva Sütt, MSc, 2004, superv. Erkki Truve, Merike Meier. The RNA-binding properties of cocksfoot mottle sobemovirus polyprotein. Tallinna Tehnikaülikool

Marju Buschmann, MSc, 2003, superv. Erkki Truve, Lenne Nigul. RNaas L-i inhibiitori geenile sarnaste avatud lugemisraamide uuriminhe müürloogas. Tallinna Tehnikaülikool

Anu Tiidema, MSc, 2001, superv. Erkki Truve, Kadri Järve. Taimede regeneratsioon ja geneetiline transformatsioon mõnedel kohalikel rukki- ja odrasortidel. Eesti Põllumajandusülikool

Tiina Tamm, PhD, 2000, superv. Erkki Truve. Cocksfoot mottle virus: the genome organisation and translational strategies. Tartu Ülikool

Kadri Tomasson, MSc, 1999, superv. Erkki Truve. Kartulimugulaviroidi (PSTV) replikatsioon ja lokalisatsioon tomatis. Tartu Ülikool

Merike Meier, MSc, 1999, superv. Erkki Truve, Tiina Tamm. Expression of cocksfoot mottle virus proteins in insect cells. Tallina Tehnikaülikool

Marie-Lise Bouscaren, MSc, 1996, superv. Erkki Truve. The importance of potato virus X coat protein in virus resistance and symptom development. Tartu Ülikool

Tiina Tamm, MSc, 1994, superv. Erkki Truve. Characterization of cocksfoot mottle virus. Tartu Ülikool

13.Current research program Molecular characterization of plant sobemoviruses, plant virus vectors.
RNA silencing and its suppressors in plants.
Microfilament system in plants.
Wheat resistance genes.
14.Current grant funding 2005-2007 The European Commission 6. Framework coordination action FOOD-CT-2004-514048 “Coordination and research on genetic resistance to plant pathogenic viruses, and their vectors, in European crops”
2002-2005 The European Commission 5. Framework RTD project QLG2-CT-2002-01673 “Virus-Induced gene Silencing: unravelling the basis of a mechanism and its exploitation for the analysis of a multitude of individual gene functions in plants”
2003-2007 Estonian Ministry of Education and Research “The expression and function of plant and plant virus genes”
2003-2007 Estonian Ministry of Agriculture “Molecular and cell culture methods in plant breeding and in the analysis of plant-derived samples”
2004-2007 Estonian Science Foundation “Post-transcriptional gene silencing and its suppressors”
2004-2007 Estonian Science Foundation “Construction of environmentally safe plant virus vectors”
15.List of most important publications

Meier, M., Paves, H., Olspert, A., Tamm, T., Truve, E. 2005. P1 protein of Cocksfoot mottle virus is indispensable for the systemic spread of the virus. Virus Genes, in press.

Nigul, L., Olspert, A., Meier, M., Paves, H., Talpsep, T., Truve, E. 2004. New plant vectors for protein tagging with E2 epitope. Plant Mol. Biol. Rep. 22:399-407.

Paves, H., Truve, E. 2004. Incorporation of mammalian actin into microfilaments in plant cell nucleus. BMC Plant Biol. 4:7.

Tiidema, A., Truve, E. 2004. Efficient regeneration of fertile barley plants from callus cultures of several Nordic cultivars. Hereditas 140:171-176.

Truve, E. Genus: Sobemovirus. 2004. In: Viruses and Virus Diseases of Poaceae (Gramienae). Lapierre H., Signoret P.-A., eds. INRA Editions.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 2001. Reconstitution of multiple virus resistance in transgenic plants. GR patent 3035873.

Mäkinen, K., Mäkeläinen, K., Arshava, N., Tamm, T., Merits, A., Truve, E., Zavriev, S., Saarma, M. 2000. Characterisation of VPg and the polyprotein processing of Cocksfoot mottle virus (genus Sobemovirus). J. gen. Virol. 81:2783-2789.

Sarmiento, C., Hunt, R., Merits, A., Paves, H., Järvekülg, L., Truve, E. 2000. Subcellular localization of five potato A potyvirus proteins. In: Proc. of the 5th Congress of the European Foundation for Plant Pathology. Taormina – Giardini Naxos. p. 300-303.

Tamm, T., Truve, E. 2000. RNA-binding activities of cocksfoot mottle sobemovirus proteins. Virus Res. 66:197-207.

Tamm, T., Truve, E. 2000. Sobemoviruses. J. Virol. 74:6231-6241.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 1999. Reconstitution of multiple virus resistance in transgenic plants. European patent 632835.

Tamm, T., Mäkinen, K., Truve, E. 1999. Identification of genes encoding for the cocksfoot mottle virus proteins. Arch. Virol. 144: 1557-1567.

Pata, I., Truve, E. 1998. Gel electrophoresis, transfer and hybridization of nucleic acids. In: Gene Manipulation Techniques. (Berzinš, V., Ed.). Springer Verlag, Berlin. 104-134.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 1998. Reconstitution of multiple virus resistance in transgenic plants. RU patent 2125606.

Tamm, T., Truve, E. 1998. Protein synthesis in cell-free systems. In: Gene Manipulation Techniques. (Berzinš, V., Ed.). Springer Verlag, Berlin. 145-163.

Tamm, T., Truve, E., Mäkinen, K., Saarma, M. 1997. Expression of cocksfoot mottle virus proteins in bacterial and plant cells. FASEB J. 11: A1402.

Tomasson, K., Virumäe, K., Truve, E. 1997. On Agrobacterium-mediated genetic transformation of barley. FASEB J. 11: A1102.

Truve, E., Næss, V., Blystad, D. R., Järvekülg, L., Mäkinen, K., Tamm, T., Munthe, T. 1997. Detection of cocksfoot mottle virus particles and RNA in oat plants by immunological, biotechnical and electronmicroscopical techniques. Arch. Phytopath. Pflanz. 30: 473-485.

Saarma, M., Kelve, M., Truve, E., Teeri, T. H. 1996. Transgenic plants displaying multiple virus resistance and a process for their production. US Patent No. 5,589,625.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 1996. Reconstitution of multiple virus resistance in transgenic plants. AU patent 669130.

Saarma, M., Truve, E., Kelve. M., Teeri, T. 1996. Reconstitution of multiple virus resistance in transgenic plants. PL patent 171446.

Truve, E., Nigul, L., Teeri, T. H., Kelve, M. 1996. The effects of 2-5A on protein synthesis in wheat germ extracts and tobacco protoplasts. Nucleos. Nucleot. 15: 1097-1111.

Kuusksalu, A., Truve, E., Aaspõllu, A., Kelve, M., Scheffer, U., Müller, W. E. G. 1995. Impairment of intracellular antiviral defence with age: age-dependent changes in expression of interferon-induced and double-stranded RNA-activated 2-5A synthetase in rat. Mech. Ageing Dev. 78: 103-115.

Mäkinen, K., Næss, V., Tamm. T., Truve, E., Aaspõllu, A., Saarma, M. 1995. The putative replicase of the cocksfoot mottle sobemovirus is translated as a part of the polyprotein by -1 ribosomal frameshift. Virology 207: 566-571.

Mäkinen, K., Tamm, T., Næss, V., Truve, E., Puurand, Ü., Munthe, T., Saarma, M. 1995. Characterization of cocksfoot mottle sobemovirus genomic RNA and its sequence comparison with related viruses. J. gen. Virol. 76: 1817-1825.

Truve, E., Järvekülg, L., Bouscaren, M.-L., Aaspõllu, A., Priimägi, A., Saarma, M. 1995. Different propagation levels of potato virus X (PVX) isolates in PVX coat protein expressing tobacco plants and protoplasts do not correlate with coat protein sequence similarities. Arch. Phytopath. Pflanz. 30: 15-30.

Kelve, M., Truve, E., Aaspõllu, A., Kuusksalu, A., Dapper, J., Perovic, S., Müller, W. E. G. 1994. Reduction of 2’-5’-oligoadenylate synthetase mRNA level in rat pheochromocytoma PC12 cells during apoptosis. In: Use of Aquatic Invertebrates as Tools for Monitoring of Environmental Hazards. (Müller, W. E. G., Ed.). Gustav Fisher Verlag, Stuttgart. 97-108.

Kelve, M., Truve, E., Aaspõllu, A., Kuusksalu, A., Dapper, J., Perovic, S., Müller, W. E. G., Schröder, H. C. 1994. Rapid reduction of mRNA coding for 2'-5'-oligoadenylate synthetase in rat pheochromocytoma PC12 cells during apoptosis. Cell. mol. Biol. 40: 165-173.

Saarma, M., Truve, E., Seppänen, P. 1994. Transgenic plants transformed with murine 2-5A synthetase gene are protected to several RNA viruses. Univ. Helsinki Dep. Plant Prod. Publ. 43: 11-12.

Truve, E., Kelve, M., Aaspõllu, A., Kuusksalu, A., Seppänen, P., Saarma, M. 1994. Principles and background for the construction of transgenic plants displaying multiple virus resistance. Arch. Virol. S9: 41-50.

Truve, E., Kelve, M., Aaspõllu, A., Schröder, H. C., Müller, W. E. G. 1994. Homologies between different forms of 2-5A synthetase. Progr. Mol. Subcell. Biol. 14: 139-149.

Truve, E., Aaspõllu, A., Honkanen, J., Puska, R., Mehto, M., Hassi, A., Teeri, T. H., Kelve, M., Seppänen, P., Saarma, M. 1993. Transgenic potato plants expressing mammalian 2'-5' oligoadenylate synthetase are protected from potato virus X infection under the field conditions. Bio/Technology 11: 1048-1052.

Saichenko, T. A., Sherbatenko, I. S., Truve, E., Kanevsky, I. F., Gleba, Yu. Yu. 1992. Resistance to transgenic tobacco plants expressing gene of (2'-5') oligoadenylate synthetase in mouse tobacco mosaic virus. Dokl. Akad. Nauk Ukr., No. 9, 145-148.

Kelve, M., Truve E., Priimägi, A., Järvekülg, L., Saarma, M. 1991. Studies on virus resistance in plants. In: UNESCO Regional Office for Science and Technology for Europe. Technical Report No. 6: International Symposium "Virology, Immunology and Society". ROSTE, Venice. 273-285.

last updated: 06.10.2005

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