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Elulookirjeldus (CV)
1.Eesnimi Toomas
2.Perekonnanimi Asser
3.Töökoht Tartu Ülikool, Närvikliinik
4.Ametikoht korraline neurokirurgia professor, kliiniku juhataja
5.Sünniaeg 14.07.1954 (päev.kuu.aasta)
6.Haridus kõrgem, Tartu Ülikooli arstiteaduskond, 1973-1979.a.
7.Teenistuskäik Tartu Ülikooli Närvikliiniku assistent 1979-1989
Tartu Ülikooli Närvikliiniku dotsent 1989-1995
Tartu Ülikooli Närvikliiniku korraline neurokirurgia professor alates 15.12.1995
Tartu Ülikooli Närvikliiniku juhataja - alates 01.09.1996
Kõrgema kategooria neurokirurg. Tunnistus: 289, 20.12.1993
8.Teaduskraad meditsiinikandidaat
9.Teaduskraadi välja
andnud asutus, aasta
Kaitsmine Moskva N. Burdenko nim. Neurokirurgia Instituudis, 27.01.1987
10.Tunnustused Tohoku Meditsiiniühingu austustunnistus (Sendai, Jaapan) 1997 a.
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
Tartu Ülikooli arstiteaduskonna dekaan, alates mai 2000 Tartu Ülikooli nõukogu liige, alates 1997
Tartu Ülikooli eelarvekomisjoni liige, alates 1999.
Tartu Ülikooli valitsuse liige, alates 2000
Tartu Ülikooli arstiteaduskonna nõukogu liige, alates 1996
12.Juhendamisel kaitstud
väitekirjad

Aive Liigant, PhD, 2004, juh. Toomas Asser, Ain-Elmar Kaasik. "Kesknärvisüsteemi primaarsete kasvajate epidemioloogia Eestis 1986-1996, kliinilised iseärasused, haigestumus, elulemus ja prognoosi mõjutavad tegurid", “Epidemiology of Primary Central Nervous Tumours in Estonia from 1986 to 1996. Clinical Characteristics, Incidence, Survival and Prognostic Factors”. Tartu Ülikool

Andres Kulla, PhD, 2004, juh. Toomas Asser. “Inimese astrotsütaarsete glioomide mesenhümaalse strooma molekulaarsed iseärasused”, “Molecular characteristics of mesenchymal stroma in human astrocytic gliomas” . Tartu Ülikool

Leena Puksa, PhD, 2003, juh. Toomas Asser, Erik Stalberg. “Hilisvastused motoorsete närvide juhtekiiruste mõõtmisel. F-lained ja A lained tervetel ja polüneuropaatiate korral”, “Late responses in motor nerve conduction studies. F waves and A waves in normal subjects and patients with neuropathies". Tartu Ülikool

Pille Taba, PhD, 2003, juh. Toomas Asser. “Parkinsoni tõve epidemioloogia Tartus, Eestis: levimus, haigestumus, kliinik ja farmakoepidemioloogia”, “Epidemiology of Parkinson's disease in Tartu, Estonia: Prevalence, incidence, clinical characteristics, and pharmacoepidemiology” . Tartu Ülikool

Tõnu Rätsep, PhD, 2002, juh. Toomas Asser. "Peaaju hemodünaamika mitteinvasiivne uurimine aneurüsmaatilise subarahnoidaalse hemorraagiaga haigetel", “Aneurysmal subarachnoid haemorrhage: noninvasive monitoring of cerebral haemodynamics”. Tartu Ülikool

Priit Eelmäe, MSc, 1996, juh. Toomas Asser. "Lihasjõu ja toonuse muutused diskogeense lumbosakraalse radikulopaatiaga haigetel pärast diskektoomiat", “Muscle strength and muscle tone in patients with discogenic lumbar radiculopathy after discectomie”. Tartu Ülikool

13.Teadustöö põhisuunad Ajuverevoolu muutused aneurüsmaatilise spontaanse subarahnoidaalse verevalanduse korral, ajuarterite aneurüsmide ravi
Parkinsoni tõve epidemioloogia ja ravi
Peaaju kasvajate epidemioloogia, malignisatsioonimehanismid
14.Jooksvad grandid Grant 5446. Rakuvälise maatriksi valkude ja proteolüütiliste ensüümide regulatsiooni mehhanismide analüüs glioomide invasioonis ning glioomide eksperimentaalne teraapia.
15.Teaduspublikatsioonid

Areda T., Kõks S., Philips M.-A. Vasar E., Karis A., Asser T. Alterations in opioid system of the rat brain after cat odor exposure. Neuroscience Letters, 2005; 377: 136-139.

Taba P, Asser T. Epidemiology of Parkinson's disease. Reviews of Clinical Gerontology. 2005; 14: 1-18.

Asser T., Linnamägi Ü. Telemedicine in Baltic Sea region: experiences of Tartu University and future challenges. CMJ 2004; 45:523-525.

F Köhler, P Fotuhi, C Schierbaum, M Dietel, W Konertz, G Baumann, T Asser Gesundheitstelematik/Telemedizin in der Republik Estland. Dtsch Med Wochenschr 2004; 129:S17-S20.

Teesalu T., Kulla A., Simisker A., Sirén V., Lawrence D., Asser T., Vaheri A. Tissue plasminogen activator and neuroserpin are widely expressed in human central nervous system. Thrombosis and Haemostasis, 2004 Aug; 92(2):358-68.

Toomela A., Pulver A., Tomberg T., Orasson A., Tikk A., Asser T. Possible Interpretation of Subjective Complaints in Patients With Spontaneous Subarachnoid Haemorrhage J Rehabil Med. 2004; 36: 63–69

Kulla A., Burkhardt K., Meyer-Puttlitz B., Teesalu T., Asser T., Wiestler O.T., Becker A.J. Analysis of the TP53 gene in laser microdissected glioblastoma vasculature. Acta Neuropathol (Berl). 2003 Apr;105(4):328-32. Epub 2003 Feb 14.

Taba P., Asser T. Incidence of Parkinson disease in Estonia. Neuroepidemiology, 2003; 22:41-45.

Teesalu T, Kulla A, Asser T, Simisker A, Vaheri A. Plasminogen Activators in CNS Physiology and Disease. p. 251-269, Nov. 2003. In: Plasminogen, structure, activation, regulation, ed. David M Waisman, Kluwer Academic Pub.

Kulla A., Teesalu T., Simisker A., Asser T. Molecular mechanisms of invasion of astrocytic tumours. Review. In: Neuropathology – back to the roots. Shaker Verlag, Aachen, 2002: 1-20

Rätsep T., Eelmäe J., Asser T. Routine utilization of the transient hyperaemic response test after aneurysmal subarachnoid haemorrhage. ICP XI. J Pickard, M. Scoznica. (eds), Acta Neurochirurgica by Springer Verlag, 2002;121-5.

Taba P., Asser T. Prevalence of Parkionson disease in Estonia. Acta Neurologica Scand 2002, 106, 5, 276-281

Teesalu T, Kulla A, Asser T, Koskiniemi M, Vaheri A. Tissue plasminogen activator as a key effector in neurobiology and neuropathology. Biochem Soc Trans 2002 Apr;30(2):183-9.

Liigant A., Haldre S., Õun A., Linnamägi Ü., Saar A., Asser T. Seizure Disorders in Patients with Intracranial Tumor. European Neurology. 2001;45-:46-51.

Liigant A, Kulla A, Linnamagi U, Asser T, Kaasik A Survival of patients with primary CNS tumours in Estonia. Eur J Cancer 2001;37(15):895-903.

Rätsep T., Asser T. Cerebral hemodynamic impairmane after aneurysmal subarachnoid hemorrhaga as evaluated by transcranial doppler ultrasound: relations to delayed cerebral ischemia and clinical outcome. J Neurosurgery, 2001 Sep;95(3):393-401

Tomberg T., Orasson A., Linnamagi U., Toomela A., Pulver A., Asser T. Coping strategies in patients following subrachnoid haemorrhage. Acta Neurol Scand 2001;104:148-155.

Kulla A., Liigant A., Piirsoo A., Rippin G., Asser T. Tenascin expression and cells of monocyte lineage: relationship in human gliomas. Modern Pathology.2000;13(1):56-67.

Liigant A., Asser T., Kulla A., Kaasik A.-E.. Epidemiology of Primary Central Nervous System Tumors in Estonia. Neuroepidemiology. 2000;19:300-311.

Bachmann T., Asser T., Sarv M., Taba P., Lausvee E., Põder E., Kahusk N., Reitsnik T. The Speed Of Elementary Visual Recognition Operations In Parkinson's Disease As Measured By The Mutual Masking Method. J of Clinical and Experimental Neuropsychology. 1998;20,1:118-134.

Ikeda H, Asser T., Yoshimoto T. Proliferation and Differentiation of Transplanted Embryonic Diencephalon in the Brain of Adult Rats. Restorative Neurology and Neuroscience.1994;7:79-87.

viimati muudetud: 09.10.2005

Curriculum Vitae (CV)
1.First Name Toomas
2.Surname Asser
3.Institution University of Tartu, Department of Neurology and Neurosurgery
4.Position Chairman, professor of neurosurgery
5.Date of birth 14.07.1954 (day.month.year)
6.Education University of Tartu, Faculty of Medicine, 1973-1979
7.Research and
professional experience
Clinical clerkship, assistant, Department of Neurology and Neurosurgery, University of Tartu, 1979-1989
Research fellow, Division of Neurosurgery, Institute fo Brain Diseases, Tohoku University, School of Medicine, Sendai, Japan, 1988-1989
University of Tartu, Department of Neurology and Neurosurgery, docent, 1989-1995·
University of Tartu, Department of Neurology and Neurosurgery, professor, since 15.12.1995·
University of Tartu, Department of Neurology and Neurosurgery, chairman, since 01.09.1996
Neurosurgeon, highest qualification, certificate 289, 20.12.1993
8.Academic degree Ph.D.
9.Dates and sites of
earning the degrees
Moscow Neurosurgical Institute (Burdenko Institute), 27.01.1987
10.Honours/awards Honour member of the Tohoku Medical Society, Sendai Japan. Testimonial from Tohoku Medical Society. Date of issue: March 24, 1997
11.Research-administrative
experience
Dean of the Medical Faculty, University of Tartu, since May 2000
Member of Tartu University council, since 1997
Member of the academic committee of Tartu University council 1997-1999
Memeber of the financial planning committee of Tartu University council 1999
Member of Tartu University government, since 2000
12.Supervised dissertations

Aive Liigant, PhD, 2004, superv. Toomas Asser, Ain-Elmar Kaasik. "Kesknärvisüsteemi primaarsete kasvajate epidemioloogia Eestis 1986-1996, kliinilised iseärasused, haigestumus, elulemus ja prognoosi mõjutavad tegurid", “Epidemiology of Primary Central Nervous Tumours in Estonia from 1986 to 1996. Clinical Characteristics, Incidence, Survival and Prognostic Factors”. Tartu Ülikool

Andres Kulla, PhD, 2004, superv. Toomas Asser. “Inimese astrotsütaarsete glioomide mesenhümaalse strooma molekulaarsed iseärasused”, “Molecular characteristics of mesenchymal stroma in human astrocytic gliomas” . Tartu Ülikool

Leena Puksa, PhD, 2003, superv. Toomas Asser, Erik Stalberg. “Hilisvastused motoorsete närvide juhtekiiruste mõõtmisel. F-lained ja A lained tervetel ja polüneuropaatiate korral”, “Late responses in motor nerve conduction studies. F waves and A waves in normal subjects and patients with neuropathies". Tartu Ülikool

Pille Taba, PhD, 2003, superv. Toomas Asser. “Parkinsoni tõve epidemioloogia Tartus, Eestis: levimus, haigestumus, kliinik ja farmakoepidemioloogia”, “Epidemiology of Parkinson's disease in Tartu, Estonia: Prevalence, incidence, clinical characteristics, and pharmacoepidemiology” . Tartu Ülikool

Tõnu Rätsep, PhD, 2002, superv. Toomas Asser. "Peaaju hemodünaamika mitteinvasiivne uurimine aneurüsmaatilise subarahnoidaalse hemorraagiaga haigetel", “Aneurysmal subarachnoid haemorrhage: noninvasive monitoring of cerebral haemodynamics”. Tartu Ülikool

Priit Eelmäe, MSc, 1996, superv. Toomas Asser. "Lihasjõu ja toonuse muutused diskogeense lumbosakraalse radikulopaatiaga haigetel pärast diskektoomiat", “Muscle strength and muscle tone in patients with discogenic lumbar radiculopathy after discectomie”. Tartu Ülikool

13.Current research program Cerebral haemodynamics after aneurysmal subarachnoid haemorrhage
Epidemiology and treatment of Parkinson’s disease
Epidemiology and malignisation mechanisms of brain tumors
14.Current grant funding Regulation of extracellular matrix proteins and proteases during progression of maligant gliomas: from understanding of basic mechanisms to experimental theraphy.
15.List of most important publications

Areda T., Kõks S., Philips M.-A. Vasar E., Karis A., Asser T. Alterations in opioid system of the rat brain after cat odor exposure. Neuroscience Letters, 2005; 377: 136-139.

Taba P, Asser T. Epidemiology of Parkinson's disease. Reviews of Clinical Gerontology. 2005; 14: 1-18.

Asser T., Linnamägi Ü. Telemedicine in Baltic Sea region: experiences of Tartu University and future challenges. CMJ 2004; 45:523-525.

F Köhler, P Fotuhi, C Schierbaum, M Dietel, W Konertz, G Baumann, T Asser Gesundheitstelematik/Telemedizin in der Republik Estland. Dtsch Med Wochenschr 2004; 129:S17-S20.

Teesalu T., Kulla A., Simisker A., Sirén V., Lawrence D., Asser T., Vaheri A. Tissue plasminogen activator and neuroserpin are widely expressed in human central nervous system. Thrombosis and Haemostasis, 2004 Aug; 92(2):358-68.

Toomela A., Pulver A., Tomberg T., Orasson A., Tikk A., Asser T. Possible Interpretation of Subjective Complaints in Patients With Spontaneous Subarachnoid Haemorrhage J Rehabil Med. 2004; 36: 63–69

Kulla A., Burkhardt K., Meyer-Puttlitz B., Teesalu T., Asser T., Wiestler O.T., Becker A.J. Analysis of the TP53 gene in laser microdissected glioblastoma vasculature. Acta Neuropathol (Berl). 2003 Apr;105(4):328-32. Epub 2003 Feb 14.

Taba P., Asser T. Incidence of Parkinson disease in Estonia. Neuroepidemiology, 2003; 22:41-45.

Teesalu T, Kulla A, Asser T, Simisker A, Vaheri A. Plasminogen Activators in CNS Physiology and Disease. p. 251-269, Nov. 2003. In: Plasminogen, structure, activation, regulation, ed. David M Waisman, Kluwer Academic Pub.

Kulla A., Teesalu T., Simisker A., Asser T. Molecular mechanisms of invasion of astrocytic tumours. Review. In: Neuropathology – back to the roots. Shaker Verlag, Aachen, 2002: 1-20

Rätsep T., Eelmäe J., Asser T. Routine utilization of the transient hyperaemic response test after aneurysmal subarachnoid haemorrhage. ICP XI. J Pickard, M. Scoznica. (eds), Acta Neurochirurgica by Springer Verlag, 2002;121-5.

Taba P., Asser T. Prevalence of Parkionson disease in Estonia. Acta Neurologica Scand 2002, 106, 5, 276-281

Teesalu T, Kulla A, Asser T, Koskiniemi M, Vaheri A. Tissue plasminogen activator as a key effector in neurobiology and neuropathology. Biochem Soc Trans 2002 Apr;30(2):183-9.

Liigant A., Haldre S., Õun A., Linnamägi Ü., Saar A., Asser T. Seizure Disorders in Patients with Intracranial Tumor. European Neurology. 2001;45-:46-51.

Liigant A, Kulla A, Linnamagi U, Asser T, Kaasik A Survival of patients with primary CNS tumours in Estonia. Eur J Cancer 2001;37(15):895-903.

Rätsep T., Asser T. Cerebral hemodynamic impairmane after aneurysmal subarachnoid hemorrhaga as evaluated by transcranial doppler ultrasound: relations to delayed cerebral ischemia and clinical outcome. J Neurosurgery, 2001 Sep;95(3):393-401

Tomberg T., Orasson A., Linnamagi U., Toomela A., Pulver A., Asser T. Coping strategies in patients following subrachnoid haemorrhage. Acta Neurol Scand 2001;104:148-155.

Kulla A., Liigant A., Piirsoo A., Rippin G., Asser T. Tenascin expression and cells of monocyte lineage: relationship in human gliomas. Modern Pathology.2000;13(1):56-67.

Liigant A., Asser T., Kulla A., Kaasik A.-E.. Epidemiology of Primary Central Nervous System Tumors in Estonia. Neuroepidemiology. 2000;19:300-311.

Bachmann T., Asser T., Sarv M., Taba P., Lausvee E., Põder E., Kahusk N., Reitsnik T. The Speed Of Elementary Visual Recognition Operations In Parkinson's Disease As Measured By The Mutual Masking Method. J of Clinical and Experimental Neuropsychology. 1998;20,1:118-134.

Ikeda H, Asser T., Yoshimoto T. Proliferation and Differentiation of Transplanted Embryonic Diencephalon in the Brain of Adult Rats. Restorative Neurology and Neuroscience.1994;7:79-87.

last updated: 09.10.2005

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