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Elulookirjeldus (CV)
1.Eesnimi Mai
2.Perekonnanimi Ots
3.Töökoht Tartu Ülikool
4.Ametikoht dotsent
5.Sünniaeg 28.09.1958 (päev.kuu.aasta)
6.Haridus kõrgem
7.Teenistuskäik Põltsamaa Haigla 1985-1988
Tartu Kiirabi 1988-1989
Tartu Ülikool, arstiteaduskond 1989-1992
Tartu Ülikool, doktorantuur 1992-1997
Tartu Ülikool, assistent1997-1999
Tartu Ülikool, dotsent al.1999
8.Teaduskraad meditsiinidoktor
9.Teaduskraadi välja
andnud asutus, aasta
Tartu Ülikool, 1998
10.Tunnustused Nefroloogia maailmaorganisatsiooni (International Society of Nephrology) stipendium stažeerimiseks USA-s Harvardi ülikooli juures 1995-1997
11.Teadusorganisatsiooniline
ja –administratiivne
tegevus
Nefroloogia maailmaorganisatsioon
Euroopa Dialüüsi ja Transplantatsiooni Ühing
Eesti Arstide Liit
Eesti Nefroloogide Selts
Eesti Kudede ja Transplantatsiooni Ühing
12.Juhendamisel kaitstud
väitekirjad

Marina Aunapuu, DSc, 2004, juh. T. Suuroja, M. Ots, A. Arend. Morphological changes in the Wistar rat kidney after renal mass ablation, low-dose irradiation and treatment. Tartu Põllumajandusülikool

Ülle Pechter, DSc, 2004, juh. J. Maaroos, M. Ots, M. Zilmer. Progression prevention strategies in hypertension and renal disease. Tartu Ülikool

13.Teadustöö põhisuunad Krooniline neerupuudulikkus: epidemioloogia, progresseerumine, patofüsioloogia, rehabilitatsioon
Hüpertensiooni patoloogia, geneetika
Transplantatsioonijärgsed infektsioonid, transplantaadi kroonilise kahjustuse progresseerumine
14.Jooksvad grandid ETF 5493 "Eksperimentaalne neeru isheemia-reperfusiooni kahjustus"
TARSK 0472 "Transplantatsioonijärgne neeruhaiguse progresseerumine"
15.Teaduspublikatsioonid

Aunapuu M, Pechter U, Kuhnel W, Ots M, Arend A. Morphological changes in experimental postischemic rat kidney. A pilot study. Ann Anat. 2005 Mar;187(1):63-70

Aunapuu M, Arend A, Kolts I, Egerbacher M, Ots M. Decrease in laminin content and protein excretion rate after five sixths nephrectomy and low-dose irradiation in the rat. Ann Anat. 2004 Apr;186(2):127-31.

Aunapuu M, Pechter U, Gerskevits E, Marjamagi MM, Suuroja S, Arend A, Kolts I, Kuhnel W, Ots M. "Low-dose radiation modifies the progression of chronic renal failure" Ann Anat. 2004 Jun;186(3):277-82

Ots M, Troy J, Rennke HG, Mackenzie HS, Brenner BM. Impact of the supplementation of kidney mass on blood pressure and progression of kidney disease. Nephrol Dial Transplant 2004 19:337-341

Pechter Ü, Aunapuu M, Riispere Z, Vihalemm T, Kullisaar T, Zilmer K, Zilmer M, Ots M. Oxidative stress status in early stages of experimental renal failure Nephron Exp Nephrol. 2004;97(2):e33-7.

A. Aunapuu, Ü. Pechter, A. Arend, T. Suuroja, M. Ots "Ultrastructural changes in the remnant kidney (after 5/6 nephrectomy) glomerulus after losartan and atenolol treatment".Medicina (Kaunas). 2003; 39(10): 975-9.

Aunapuu M, Pechter Ülle, Roosaar P, Gershkevich E, Marjamägi MM, Arend A, Kolts I, Ots M. "Morphological changes in the kidney after 5/6 nephrectomy and low-dose radiation" Tsitologiia. 2003;45(6):555-63

Pechter, Ots Mesikepp, Zilmer K, Kullisaar T, Vihalemm T, Zilmer M, Maaroos J. Beneficial effects of water-based exercise in patients with chronic kidney disease.Int J Rehabil Res. 2003 Jun; 26(2): 153-6.

Ülle Pechter, Jaak Maaroos, Siiri Mesikepp, Alar Veraksits and Mai Ots "Regular Low-intensity Aquatic Exercise Improves Cardiorespiratory Functional Capacity and Reduces Proteinuria in Chronic Renal Failure Patients" Nephrol Dial Transplant. 2003 Mar; 18(3): 624-5.

Locatelli F, D'Amico M, Cernevskis H, Dainys B, Miglinas M, Luman M, Ots M, Ritz E. The epidemiology of end-stage renal disease in the Baltic countries: an evolving picture.Nephrol Dial Transplant. 2001 Jul;16(7):1338-42.

Ots M, Kulla A, Luman M, Metskula K, Leiba V, Ritz E. Non-diabetic nodular glomerulosclerosis recurring in a renal graft.Nephrol Dial Transplant. 2000 Dec;15(12):2053-6.

Ots M, Pechter U, Tamm A. Characteristics of progressive renal disease.Clin Chim Acta. 2000 Jul;297(1-2):29-41. Review.

Kato S, Luyckx VA, Ots M, Lee KW, Ziai F, Troy JL, Brenner BM, MacKenzie HS. Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats.Kidney Int. 1999 Sep;56(3):1037-48.

Ots M, Uibo O, Metskula K, Uibo R, Salupere V. IgA-antigliadin antibodies in patients with IgA nephropathy: the secondary phenomenon?Am J Nephrol. 1999;19(4):453-8.

Kull K, Salupere R, Uibo R, Ots M, Salupere V. Antineutrophil cytoplasmic antibodies in Estonian patients with inflammatory bowel disease. Prevalence and diagnostic role.Hepatogastroenterology. 1998 Nov-Dec;45(24):2132-7.

Ots M, Mackenzie HS, Troy JL, Rennke HG, Brenner BM. Effects of combination therapy with enalapril and losartan on the rate of progression of renal injury in rats with 5/6 renal mass ablation.J Am Soc Nephrol. 1998 Feb;9(2):224-30.

Mackenzie HS, Ots M, Ziai F, Lee KW, Kato S, Brenner BM. Angiotensin receptor antagonists in experimental models of chronic renal failure. Kidney Int Suppl. 1997 Dec;63:S140-3

Ots M, Salupere V, Uibo R. Regional incidence of rapidly progressive glomerulonephritis in Estonia. Nephrol Dial Transplant. 1997 Dec;12(12):2794-6

Ziai F, Ots M, Provoost AP, Troy JL, Rennke HG, Brenner BM, Mackenzie HS. The angiotensin receptor antagonist, irbesartan, reduces renal injury in experimental chronic renal failure. Kidney Int Suppl. 1996 Dec;57:S132-6

viimati muudetud: 03.08.2005

Curriculum Vitae (CV)
1.First Name Mai
2.Surname Ots
3.Institution University of Tartu
4.Position docent
5.Date of birth 28.09.1958 (day.month.year)
6.Education higher
7.Research and
professional experience
Põltsamaa Hospital 1985-1988
Tartu First Aid dept 1988-1989
University of Tartu, arstiteaduskond 1989-1992
University of Tartu, graduate student 1992-1997
University of Tartu, an assistant1997-1999
University of Tartu, a docent from1999
8.Academic degree doctor of medical sciences
9.Dates and sites of
earning the degrees
University of Tartu, 1998
10.Honours/awards Internationa Society of Nephrology, clinical fellowship training award, Harvard Medical School, 1995-1997
11.Research-administrative
experience
International Society of Nephrology
European dialysis and transplantation association
Estonian Physician Association
Estonian Society of Nephrology
Estonian Transplantation Association
12.Supervised dissertations

Marina Aunapuu, DSc, 2004, superv. T. Suuroja, M. Ots, A. Arend. Morphological changes in the Wistar rat kidney after renal mass ablation, low-dose irradiation and treatment. Tartu Põllumajandusülikool

Ülle Pechter, DSc, 2004, superv. J. Maaroos, M. Ots, M. Zilmer. Progression prevention strategies in hypertension and renal disease. Tartu Ülikool

13.Current research program Progression of chronic renal failure: epidemiology, progression, patophysiology, rehabilitation
Hypertension: pathophysiology, genetics
Post-transplant infections, progression of chronic transplant nephropathy
14.Current grant funding 1. Estonian Scientific Foundation: "IExperimental renal ischemia-reperfusion injury"
2. Ministry of Science and Education: "Post-transplant renal disease progression"
15.List of most important publications

Aunapuu M, Pechter U, Kuhnel W, Ots M, Arend A. Morphological changes in experimental postischemic rat kidney. A pilot study. Ann Anat. 2005 Mar;187(1):63-70

Aunapuu M, Arend A, Kolts I, Egerbacher M, Ots M. Decrease in laminin content and protein excretion rate after five sixths nephrectomy and low-dose irradiation in the rat. Ann Anat. 2004 Apr;186(2):127-31.

Aunapuu M, Pechter U, Gerskevits E, Marjamagi MM, Suuroja S, Arend A, Kolts I, Kuhnel W, Ots M. "Low-dose radiation modifies the progression of chronic renal failure" Ann Anat. 2004 Jun;186(3):277-82

Ots M, Troy J, Rennke HG, Mackenzie HS, Brenner BM. Impact of the supplementation of kidney mass on blood pressure and progression of kidney disease. Nephrol Dial Transplant 2004 19:337-341

Pechter Ü, Aunapuu M, Riispere Z, Vihalemm T, Kullisaar T, Zilmer K, Zilmer M, Ots M. Oxidative stress status in early stages of experimental renal failure Nephron Exp Nephrol. 2004;97(2):e33-7.

A. Aunapuu, Ü. Pechter, A. Arend, T. Suuroja, M. Ots "Ultrastructural changes in the remnant kidney (after 5/6 nephrectomy) glomerulus after losartan and atenolol treatment".Medicina (Kaunas). 2003; 39(10): 975-9.

Aunapuu M, Pechter Ülle, Roosaar P, Gershkevich E, Marjamägi MM, Arend A, Kolts I, Ots M. "Morphological changes in the kidney after 5/6 nephrectomy and low-dose radiation" Tsitologiia. 2003;45(6):555-63

Pechter, Ots Mesikepp, Zilmer K, Kullisaar T, Vihalemm T, Zilmer M, Maaroos J. Beneficial effects of water-based exercise in patients with chronic kidney disease.Int J Rehabil Res. 2003 Jun; 26(2): 153-6.

Ülle Pechter, Jaak Maaroos, Siiri Mesikepp, Alar Veraksits and Mai Ots "Regular Low-intensity Aquatic Exercise Improves Cardiorespiratory Functional Capacity and Reduces Proteinuria in Chronic Renal Failure Patients" Nephrol Dial Transplant. 2003 Mar; 18(3): 624-5.

Locatelli F, D'Amico M, Cernevskis H, Dainys B, Miglinas M, Luman M, Ots M, Ritz E. The epidemiology of end-stage renal disease in the Baltic countries: an evolving picture.Nephrol Dial Transplant. 2001 Jul;16(7):1338-42.

Ots M, Kulla A, Luman M, Metskula K, Leiba V, Ritz E. Non-diabetic nodular glomerulosclerosis recurring in a renal graft.Nephrol Dial Transplant. 2000 Dec;15(12):2053-6.

Ots M, Pechter U, Tamm A. Characteristics of progressive renal disease.Clin Chim Acta. 2000 Jul;297(1-2):29-41. Review.

Kato S, Luyckx VA, Ots M, Lee KW, Ziai F, Troy JL, Brenner BM, MacKenzie HS. Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats.Kidney Int. 1999 Sep;56(3):1037-48.

Ots M, Uibo O, Metskula K, Uibo R, Salupere V. IgA-antigliadin antibodies in patients with IgA nephropathy: the secondary phenomenon?Am J Nephrol. 1999;19(4):453-8.

Kull K, Salupere R, Uibo R, Ots M, Salupere V. Antineutrophil cytoplasmic antibodies in Estonian patients with inflammatory bowel disease. Prevalence and diagnostic role.Hepatogastroenterology. 1998 Nov-Dec;45(24):2132-7.

Ots M, Mackenzie HS, Troy JL, Rennke HG, Brenner BM. Effects of combination therapy with enalapril and losartan on the rate of progression of renal injury in rats with 5/6 renal mass ablation.J Am Soc Nephrol. 1998 Feb;9(2):224-30.

Mackenzie HS, Ots M, Ziai F, Lee KW, Kato S, Brenner BM. Angiotensin receptor antagonists in experimental models of chronic renal failure. Kidney Int Suppl. 1997 Dec;63:S140-3

Ots M, Salupere V, Uibo R. Regional incidence of rapidly progressive glomerulonephritis in Estonia. Nephrol Dial Transplant. 1997 Dec;12(12):2794-6

Ziai F, Ots M, Provoost AP, Troy JL, Rennke HG, Brenner BM, Mackenzie HS. The angiotensin receptor antagonist, irbesartan, reduces renal injury in experimental chronic renal failure. Kidney Int Suppl. 1996 Dec;57:S132-6

last updated: 03.08.2005

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