| title: | HEALTH-RELATED QUALITY OF LIFE AND DISEASE-SPECIFIC QUALITY OF LIFE IN INFLAMMATORY BOWEL DISEASE - ULCERATIVE COLITIS AND CROHN DISEASE |
|---|---|
| reg no: | ETF5294 |
| project type: | Estonian Science Foundation research grant |
| subject: |
3. Medical Sciences |
| status: | completed |
| institution: | University of Tartu |
| head of project: | Riina Salupere |
| duration: | 01.01.2002 - 31.12.2004 |
| description: | Ulcerative colitis (UC) and Crohn disease (CD) are chronic inflammatory diseases with a tendency to complications and they may lead to long periods of disability with hospitalizations and prolonged drug treatment. Limitations of UC and CD activity indices have identified the need to measure health-related quality of life (HRQOL) and inflammatory bowel disease-specific quality of life (IBDQOL). Therefore, validated and tested quality of life questionnaires are important tools for inflammatory bowel disease patients management. The study aims are to give a detailed survey of HRQOL of adult UC and CD patients compared with other chronic gastrointestinal diseases as chronic liver disease and peptic ulcer disease, and to investigate IBDQOL, as judged by the CD and UC patients compared to the age- and sex-matched irritable bowel syndrome patients. HRQOL will be assessed by the SF-36 self-rating questionnaire. The SF-36 questionnaire will be completed by each UC, CD, chronic liver disease and peptic ulcer patient (self-administered survey). IBDQOL will be assessed by the McMaster IBDQOL questionnaire. The IBDQOL questionnaire will be completed by the investigator during an interview carried out with the patients with UC, CD and irritable bowel syndrome (an interviewer administered survey). Diagnosis of UC, CD, chronic liver disease, peptic ulcer disease and irritable bowel syndrome will be gathered on the basis of the patients case-reports. Assessment of QOL means that the patients`perceptions of their life-style, health, disease, treatment are being considered.This may have a considerable impact on the traditional patient-doctor relationship in which only the doctor plays an active decision-making role. Evidence-based knowledge of the quality of life serves as necessary support for patients in their attempt to cope with the fact that they have lifelong chronic disease. Measurement of HRQOL and IBDQOL can be used in health-care cost-utility analysis. |
| project group | ||||
|---|---|---|---|---|
| no | name | institution | position | |
| 1. | Riina Salupere | Department of Internal Medicine, Faculty of Medicine, University of Tartu | docent of gastroenterology | |
| 2. | Vello Salupere | Department of Internal Medicine, University of Tartu | professor emeritus | |