title: STUDY ON INJECTING DRUG USERS NEEDLES AND SYRINGES: DETECTION OF MARKERS OF HBV, HCV and HIV INFECTIONS
reg no: ETF5526
project type: Estonian Science Foundation research grant
subject: 3. Medical Sciences
status: completed
institution: TU Faculty of Medicine
head of project: Anneli Uusküla
duration: 01.01.2003 - 31.12.2004
description: Study is DESIGNED to
1) assess the acceptability and feasibility of testing residual material from used syringes/needles, as a screening strategy for infectious diseases among IDUs in Tallinn,
2) with the secondary aim of detecting the prevalence of HIV, HCV and HBV infections in used needles/syringes, and estimate the population prevalence of these infections
METHODS:
A cross-sectional study, prevalence study
Sample size and study objects
1. 250 IDUs participating anonymously assuming fictitious code names.
A short drug- and sex-related risk survey will be self-administered while returning used syringes to consenting participants
2. 400 used, returned syringes/needles to the NEP
Each needle/syringe distributed will be numbered (prelabeled).
Laboratory testing will be performed in West-Tallinn Central hospital centrum for infectious diseases HIV/AIDS reference laboratory: experienced in work with potentially infectious materials. The presence of antibodies to HIV, HCV, HBV in collected specimens (residual material from used syringes/needles) will be detected by EIA.
RESULTS According to the stated goals of the study we will assess the value of needle/syringe testing for HCV, HBV, and HIV as a marker of these infections among IDU population in Estonia. It is extremely important develope nonintrusive testing methodologies for ongoing disease surveillance, programs, interventions and evaluation of projects.

project group
no name institution position  
1.Robert HeimerYale University, USAass. professor 
2.Mihhail MorozAIDS Support Centerproject manager 
3.Valentina UstinaWest-Tallinn Central hospital center for infectiouchief of laboratory 
4.Anneli UuskülaTU Faculty of MedicineResearcher