title: Studies on the expression and function of plant and plant virus genes
reg no: SF0222604Bs03
project type: targeted financing
subject: 1.6-1.9. Chemistry and Molecular Biology
2. Engineering
4. Agricultural Sciences
status: accepted
institution: Tallinn Technical University
head of project: Erkki Truve
duration: 01.01.2003 - 31.12.2007
description: The main task of the project is to describe the mechanisms of gene silencing in higher plants and clarify the role of viruses in the process. First of all, we plan to identify plant genes which products interact with viral gene silencing suppressors. As gene silencing is studied using viral proteins, the second task of the project is to identify the biological functions of cocksfoot mottle sobemovirus (CfMV) genes and to describe the mechanisms how this particular virus affects antiviral gene silencing mechanisms in host plant. We also plan to elaborate a novel virus-induced gene silencing vector for cereals, based on the infectious cDNA clone of CfMV. In parallel with studies on sobemoviruses and gene silencing we shall study also the role of potato A potyvirus proteins P1 and HC-Pro in this novel mechanism of gene expression regulation.
Besides focusing on the studies on gene silencing mechanisms, we foresee also the application of gene silencing for the functional analysis plant genes (RNase L inhibitor) as well as gene families (myosin and myosin-like genes).

project group
no name institution position  
1.Birger IlauTallinn Technical Universityinsener/magistrant 
2.Kadri JärveTallinn Technical Universitydotsent 
3.Kristel JärveTallinn Technical Universityinsener/magistrant 
4.Lilian JärvekülgTallinn Technical Universityprofessor 
5.Jekaterina KazantsevaTallinn Technical Universityteadur/doktorant 
6.Evi KrügerTallinn Technical Universitylaborant 
7.Gabriela LasnTallinn Technical Universityteadur/doktorant 
8.Merike MeierTallinn Technical Universityteadur/doktorant 
9.Lenne NigulTallinn Technical Universityteadur 
10.Signe NõuTallinn Technical Universitylaborant 
11.Eve-Ly OjanguTallinn Technical Universityteadur 
12.Allan OlspertTallinn Technical Universityinsener/magistrant 
13.Maarja OtsusTallinn Technical Universityinsener/magistrant 
14.Heiti PavesTallinn Technical Universityvanemteadur 
15.Cecilia SarmientoTallinn Technical Universityteadur/doktorant 
16.Silva SüttTallinn Technical Universityinsener/magistrant 
17.Tiina TammTallinn Technical Universityvanemteadur 
18.Kiira TarassovaTallinn Technical Universityinsener 
19.Sirje TimmuskTallinn Technical Universitydotsent 
20.Erkki TruveTallinn Technical University 
21.Meelis ValkTallinn Technical Universitylaborant 
22.Sofia VillemsonTallinn Technical Universityvanemteadur