title: Structural and medical proteomics
reg no: SF0142501s03
project type: targeted financing
subject: 1.6-1.9. Chemistry and Molecular Biology
2. Engineering
3. Medical Sciences
status: accepted
institution: Tallinn Technical University
head of project: Peep Palumaa
duration: 01.01.2003 - 31.12.2007
description: Project integrates following projects in the field of structural and medical proteomics ain the chair of genomics and proteomics at Tallinn Technical University:
1.Structural and functional studies of key proteins participating in the zinc metabolism in the brain. Structure, functioning and interactions of brain-specific metallothionein-3 and zinc transporter ZnT-3, their role in the zinc homeostasis in the brain and search for key points of its regulation. The final aim of the project is the elaboration of a new strategy and tools for prevention and therapy of Alzheimer¿s disease through normalization of zinc metabolism in the most critical regions of the brain. Principal investigator: prof. P. Palumaa
2. Functional studies of lipoproteins. Metabolism of lipoproteins (lipoprotein lipase etc.), role of protein-protein, protein - lipid interactions in the molecular recognition and their impact in diseases on lipid metabolism like artherosclerosis. Principal investigator: Dr. A. Lõokene.

project group
no name institution position  
1.Ernest BodarenkoTallinn Technical Universitymagistrant 
2.Ernest BondarenkoTTÜ GTIlaborant/magistrant 
3.Elo EristeTallinn Technical Universityteadur,doktorant 
4.Liina KangurTallinn Technical Universityteadur,doktorant 
5.Julia KarpovaTallinn Technical Universitymagistrant 
6.Jekaterina KazantsevaTallinn Technical Universityteadur,doktorant 
7.Aivar LõokeneTallinn Technical Universityv.teadur 
8.Peep PalumaaTallinn Technical University 
9.Lesja PokrasTallinn Technical Universitymagistrant 
10.Rannar SillardTallinn Technical Universityj.teadur 
11.Julia SmirnovaTTÜ GTIlaborant/magistrant 
12.Indrek TammisteTallinn Technical Universitymagistrant