| title: | Studies on the expression and function of plant and plant virus genes |
|---|---|
| reg no: | SF0222604As03 |
| project type: | targeted financing |
| subject: |
1.6-1.9. Chemistry and Molecular Biology 2. Engineering 4. Agricultural Sciences |
| status: | accepted |
| institution: | Institute of Chemical Physics and Biophysics |
| head of project: | Erkki Truve |
| duration: | 01.01.2003 - 31.12.2007 |
| description: | The main task of the project is to describe the mechanisms of gene silencing in higher plants and clarify the role of viruses in the process. First of all, we plan to identify plant genes which products interact with viral gene silencing suppressors. As gene silencing is studied using viral proteins, the second task of the project is to identify the biological functions of cocksfoot mottle sobemovirus (CfMV) genes and to describe the mechanisms how this particular virus affects antiviral gene silencing mechanisms in host plant. We also plan to elaborate a novel virus-induced gene silencing vector for cereals, based on the infectious cDNA clone of CfMV. In parallel with studies on sobemoviruses and gene silencing we shall study also the role of potato A potyvirus proteins P1 and HC-Pro in this novel mechanism of gene expression regulation. Besides focusing on the studies on gene silencing mechanisms, we foresee also the application of gene silencing for the functional analysis plant genes (RNase L inhibitor) as well as gene families (myosin and myosin-like genes). |
| project group | ||||
|---|---|---|---|---|
| no | name | institution | position | |
| 1. | Marju Buschmann | Institute of Chemical Physics and Biophysics | insener/magistr | |
| 2. | Gabriela Lasn | Institute of Chemical Physics and Biophysics | teadur | |
| 3. | Merike Meier | Institute of Chemical Physics and Biophysics | teadur | |
| 4. | Lenne Nigul | Institute of Chemical Physics and Biophysics | teadur | |
| 5. | Eve-Ly Ojangu | Institute of Chemical Physics and Biophysics | teadur | |
| 6. | Heiti Paves | Institute of Chemical Physics and Biophysics | v.-teadur | |
| 7. | Cecilia Sarmiento | Institute of Chemical Physics and Biophysics | teadur | |
| 8. | Silva Sütt | Institute of Chemical Physics and Biophysics | insener/magistr | |
| 9. | Tiina Tamm | Institute of Chemical Physics and Biophysics | v.-teadur | |
| 10. | Erkki Truve | Institute of Chemical Physics and Biophysics | v.-teadur /Prof | |