| title: | Impact of CPAP Treatment on the Psychosomatic Condition of Apnoeic Patients and the Muscular Tone of the Soft Palate and the Lingual Muscle.. |
|---|---|
| reg no: | ETF5842 |
| project type: | Estonian Science Foundation research grant |
| subject: |
3.3. Clinical Medicine |
| status: | accepted |
| institution: | TU Faculty of Medicine |
| head of project: | Marlit Veldi |
| duration: | 01.01.2004 - 31.12.2007 |
| description: | The project will show how CPAP (Continuous Positive Airway Pressure) treatment will affect the psychosomatic condition of apnoeic patients and the tone of the soft palate and the lingual muscles. Until now in Estonia CPAP treatment has been used only on a few occasions. By comparison, in Finland there are already about 10,000 patients that receive CPAP treatment each night. The recently obtained diagnostic equipment at the Ear Clinic of the Tartu University Clinicum will allow to set an individual pressure of the CPAP device for each patient. It also allows to conduct research and provide CPAP treatment in Estonia. The study will include male and female patients, aged 30¿45 yrs, with the body mass index (BMI) >30 kg/m, who have been diagnosed with a medium or severe sleep apnoea syndrome on the basis of a polysomnographic study. For such patients CPAP treatment is the recommended method of treatment. Such a selection of subject is possible in Estonian conditions, where CPAP treatment is almost inexistent. One could predict that the health of apnoeic patients of this age group and degrees of severity will improve during sleep, and their pathophysiological condition will regress. During the CPAP treatment, a three-year period, we will assess at six-month intervals the dynamics of the somatic (bodyweight, blood pressure, cardiac activity-EKG) and psychic condition and the dynamics of the tone of the soft palate and the lingual muscle. The dynamics of the somatic and psychic conditions during CPAP treatment will show not only the effect of CPAP treatment but also the attitude to CPAP treatment in Estonian conditions. On the othe hand, the research will act as a continuation to the myometric diagnostics of the tone of the soft palate and the lingual muscle in apnoeic patients (Veldi et al. 2000 in Journal of Sleep Research; Veldi et al. 2001 in Clinical Physiology; Veldi et al. In European Archives of Oto-Rhino-Laryngology). Until now the positive effect of CPAP treatment on the dilatator muscles of the upper airway has been described but not objectivized. The myotonometric testing of the soft palate and the lingual muscles during CPAP treatment enables us to objectivize muscular dynamics. The study includes doctoral students and residents who have the necessary research experience and professional knowledge. The study will provide new and additional scientific information about the effect of CPAP treatment on the psychosomatic condition and tone of the pharyngeal muscle in apnoeic patients. The research findings will be published in peer-reviewed international medical journals. The study is necessary for Estonian medicine in order to realize the CPAP-treatment-related problems in Estonia. |
| project group | ||||
|---|---|---|---|---|
| no | name | institution | position | |
| 1. | Triin Eller | TÜ Psühhiaatriakliinik | doktorant | |
| 2. | Priit Kasenõmm | TÜ Mikrobioloogia Instituut | doktorant | |
| 3. | Mikk Mailand | SA TUK Kõrvakliinik | ||
| 4. | Arved Vain | University of Tartu | erakorraline vanemteadur | |
| 5. | Marlit Veldi | TU Faculty of Medicine | researcher, otorhinolaryngologist | |
| 6. | Tõnu Vooder | TÜ Kardiovaskulaar ja torakaalkirurgia Kliinik | doktorant, arst-õppejõud | |