| title: | Bioimpedance Based Methods for Diagnosing of Heart Ischemia and Reperfusion: A Study and Further Developments |
|---|---|
| reg no: | ETF5892 |
| project type: | Estonian Science Foundation research grant |
| subject: |
2.13. Biomedical Engineering 3.3. Clinical Medicine |
| status: | accepted |
| institution: | TTU Faculty of Information Technology |
| head of project: | Mart Min |
| duration: | 01.01.2004 - 31.12.2006 |
| description: | The response of the main group of cardiovascular deaseases (illnesses due to perfusion problems) in the electrical bioimpedance of myocardium, is the content of this work. The research is based on study of the isolated heart experimentally and by the aid of computer models connecting the both methods with theoretical paradigms of cell biology and electrical conductivity of myocardium.New microelectronic devices for bioimpedance measurement and analysis will be tested in experiments with healthy and de-seased and/or artificially modified hearts. The main goal of the project is to develop indications for applying the methods of bioimpedance diag-nosing, and to elaborate the respective technological solutions for bioimpedance based diagnosing and monitoring of heart surgery and heart transplantation procedures. The concurring aims are: 1) to find out the reasonable principles for composing the diagnosing system, keeping in view, the placement of electrodes, parametres of measurement signals, and methods of signal and data processing; 2) to put together a data base of possible deflections in the myocardium tissue and the corresponing changes in patterns of bioimpedance variations. Recommendations, and methodical and instrumental means for applications of bioimpedance based diagnosing in clinical practice in both, in surgery and post-surgery conditions, will be the results of this work. The means for diagnosing and monitoring the heart transplantation will be considered separately. The performers of this interdisciplinary work have different backgrounds. Three medical doctors and a physisist are the graduaters from Tartu University, and an electronics engineer, a physisist, and a systems engineer are the graduaters from Tallinn Technical University. The research is closely related with post graduate studies. Three PhD and at least one MSc thesis are ought to be defended during the time schedule of this work. |
| project group | ||||
|---|---|---|---|---|
| no | name | institution | position | |
| 1. | Andres Kink | Südamekliinik AS | kirurg | |
| 2. | Mart Min | TTU Faculty of Information Technology | professor | |
| 3. | Indrek Rätsep | Tallinn Technical University | doktorant | |