| title: | Epidemiology of nosocomial bloodstream infections and genetic markers of antimicrobial resistance in invasive bacterial strains |
|---|---|
| reg no: | ETF6458 |
| project type: | Estonian Science Foundation research grant |
| status: | accepted |
| institution: | University of Tartu |
| head of project: | Matti Maimets |
| duration: | 01.01.2005 - 31.12.2008 |
| description: | Nosocomial infections affect about 5-10% of all hospitalized patients, about 30% of patients in intensive care units, and are associated with substantial morbidity, mortality, increased length of stay and additional costs. The burden is even more pronounced with nosocomial bloodstream infections (NBSI), frequently caused by multresistant bacteria, with mortality rate of 25-60% and increase in length of stay for 14 days. Main Goal To study the incidence and risk factors of NBSI, the spectrum and antimicrobial resistance patterns of invasive bacterial strains, and molecular markers of resistance. To reduce the morbidity, mortality and additional costs of NBSI in Estonia. Outputs 1. The surveillance system of NBSI according to the internationally accepted criteria will be created; Estonian hospitals will join the HELICS (Hospital in Europe Link for Infection Control through Surveillance) framework; 2. Evidence-based guidelines of antibiotic therapy according to the local spectra of etiologies, antimicrobial resistance patterns and genetic markers of resistance will be implemented: 3. The PCR methods developed will be used for rapid detection and investigation of outbreaks in Estonian hospitals. |
| project group | ||||
|---|---|---|---|---|
| no | name | institution | position | |
| 1. | Krista Lõivukene | Clinicum of Tartu University | clinical bacteriologist | |
| 2. | Matti Maimets | University of Tartu | docent | |
| 3. | Paul Naaber | Clinicum of Tartu University | Head of Dept Clinical Microbiology | |
| 4. | Epp Sepp | University of Tartu | Senior Researcher | |