title: | CHARACTERIZATION OF THE GENES PROTECTING THE TRANSLATIONAL APPARATUS IN STRESS CONDITIONS |
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reg no: | ETF6768 |
project type: | Estonian Science Foundation research grant |
subject: |
1.9. Genetics, Physiology and Microbiology |
status: | accepted |
institution: | Tartu University Institute of Technology |
head of project: | Tanel Tenson |
duration: | 01.01.2006 - 31.12.2009 |
description: | Products of several genes protect the bacterial translational apparatus in stress conditions. Some of the stress response genes have been inactivated in previous studies. Unfortunately, different E.coli strains have been used for the inactivations, making comparisons of the roles of the genes difficult, as different effects could occur in different genetic backgrounds. Moreover, no standard sets of conditions have been developed for comparison of the strains. The aims of the current project are: 1. To develop standard experimental conditions for the comparisons of different E. coli knock-out strains. 2. To determine the roles of genes protecting the translational machinery (relA, spoT, rmf, relB, relE, yfiA, yhbH, sra, ssrA) in different stress conditions. |
project group | ||||
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no | name | institution | position | |
1. | Niilo Kaldalu | |||
2. | Tanel Tenson | Tartu Ülikooli Tehnoloogiainstituut |