| title: | Associations between Helicobacter pylori infection and it’s eradication with rosacea and iron deficiency anaemia (application for "My first grant") |
|---|---|
| reg no: | ETF6683 |
| project type: | Estonian Science Foundation research grant |
| subject: |
3.3. Clinical Medicine |
| status: | accepted |
| institution: | TU Faculty of Medicine |
| head of project: | Marje Oona |
| duration: | 01.01.2006 - 31.12.2009 |
| description: | Helicobacter pylori (H. pylori) infection is one of the most prevalent chronic infections in Estonia. Common poblems are iron deficiency anaemia and rosacea. Chronic H. pylori infection has been associated with the occurrence of various extradigestive diseases, incl. iron deficient anemia and rosacea. However, the role of H. pylori in the development of these diseases has not been fully elucidated due to lack of adequately controlled and statistically powered observational and experimental studies. The aim of this project is to investigate the associations of H. pylori infection with iron deficiency anaemia and rosacea. The specific aims of the project are: 1. To investigate the associations between H. pylori infection and iron deficiency in children. 2. To evaluate the effect of H. pylori eradication on iron deficiency. 3. To determine the prevalence of rosacea among working-age general population of Tartu. 4. To determine the prevalence of H. pylori infection and upper gastrointestinal symptoms in rosacea patients and in subjects without chronic skin disorders. 5. To evaluate the effect of H. pylori eradication on rosacea symptoms. In order to evaluate the associations between H. pylori infection and iron deficiency in children, an observational study and a clinical trial will be conducted. In order to evaluate the associations between H. pylori infection and rosacea, a prevalence study, a case-control study and a clinical trial will be carried out. Altogether approx. 700 children and 500 adults will be studied. The results will be both of global and local value as they are important for understanding the nature of H. pylori infection and to evidence-based indications for treatment of H. pylori infection. |
| project group | ||||
|---|---|---|---|---|
| no | name | institution | position | |
| 1. | Kristi Abram | |||
| 2. | Heli Grünberg | |||
| 3. | Heidi-Ingrid Maaroos | |||
| 4. | Marje Oona | Tartu Ülikool | ||
| 5. | Neve Vendt | |||