title: Research of Measurement Methods for Electrical Bioimpedance Spectroscopy and Application of them for Development of Means for Organ Monitoring
reg no: ETF5897
project type: Estonian Science Foundation research grant
subject: 2.13. Biomedical Engineering
status: accepted
institution: TTU Faculty of Information Technology
head of project: Toomas Parve
duration: 01.01.2004 - 31.12.2006
description: The main goal of the research is to develop methods and means for obtaining an adequate information about the quality of functioning of patients' organs, firstly of the heart but also of different transplanted tissues and organs, using multifrequency measurement and analysis of their electrical bioimpedance (EBI), and development of the microelectronic means for this.
Another serious goal will be research of the electrical equivalents of the bioimpedance of the organs and tissues, and determining of the relations between the equivalents and the results of measurement, and criterions of selecting suitable method of measurement.
On the basis of the investigations will be developed original equipment, which will be tested in laboratory and in clinical conditions.
The following tasks with expected results are derived from the goals:
1) Development of high performance portable EBI spectrometers based on application of powerful digital signal processors (DSP) enabling to carry out EBI measurements at several frequencies simultaneously.
Results: Examples of the EBI monitors, which can be used during surgery and transplantation of tissues and organs.
2) Investigation of possibilities to develop the implantable cardiac EBI monitors with the aim to develop the integrated circuits (IC) for EBI measurements with the low DC voltage supply (3 V) and low current consumption, which are suitable for implantable and portable EBI measurement devices.
Results: the pilot examples of EBI monitors, which are based on the developed microcircuits, and could be used or even be implanted together with the transplant organs.
3) Parametrisation of dynamic impedance models of the heart .
Results: More adequate computer models enabling to diagnose the state of the living organs, and also their to determine their electrical parameters.

project group
no name institution position  
1.Aivo KuhlbergTallinn Technical Universitydoktorant 
2.Alar KuusikTallinn Technical Universityvanemteadur 
3.Toomas ParveTTU Faculty of Information Technologysenior researcher